Rational inhibitor design, synthesis and NMR spectroscopic study by transferred nuclear overhauser spectroscopy of novel inhibitors of cinnamyl alcohol dehydrogenase, a critical enzyme in lignification

Journal of Enzyme Inhibition

Volumn 14, Issue 3, 1999, Pages 217-237

  Kennedy, Karen ^a   Baltas, Michel ^a   Douglas, Kenneth T ^b   Duran, Hubert ^a   Embrey, Kevin J ^b   Giraudon, Jean Guillaume ^a   McKie, James H ^b   Grima Pettenati, Jacqueline ^c   Gorrichon, Liliane ^a  

^a Université Paul Sabatier Toulouse III   (France)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

Alcohol dehydrogenase; Enzyme inhibition; Inhibitor conformation; Lignification; Phosphonates; TRNOESY

Indexed keywords

ALCOHOL DEHYDROGENASE; BENZYLAMINE; CINNAMYL ALCOHOL; ENZYME INHIBITOR; PHOSPHONIC ACID DERIVATIVE;

ARTICLE; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME SYNTHESIS; HYDROLYSIS; INHIBITION KINETICS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL;

EID: 0033067321     PISSN: 87555093     EISSN: None     Source Type: Journal    
DOI: 10.3109/14756369909030318     Document Type: Article

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