Mechanistic findings of green tea as cancer preventive for humans

Proceedings of the Society for Experimental Biology and Medicine

Volumn 220, Issue 4, 1999, Pages 225-228

  Fujiki, Hirota ^a   Suganuma, Masami ^a   Okabe, Sachiko ^a   Sueoka, Eisaburo ^a   Suga, Kenji ^a   Imai, Kazue ^a   Nakachi, Kei ^a   Kimura, Shunsaku ^b  

^a SAITAMA CANCER CENTER   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPIGALLOCATECHIN GALLATE; ESTROGEN; POLYPHENOL DERIVATIVE; PROGESTERONE; TUMOR NECROSIS FACTOR ALPHA;

BREAST CANCER; CANCER PREVENTION; CARCINOGENESIS; CONFERENCE PAPER; DRUG BIOAVAILABILITY; DRUG MECHANISM; ESTROGEN RELEASE; HUMAN; LYMPH NODE METASTASIS; NONHUMAN; OXIDATIVE STRESS; PHOSPHOLIPID MEMBRANE; PROGESTERONE RELEASE; TEA; TUMOR NECROSIS; TUMOR PROMOTION;

ANIMALIA;

EID: 0033066960     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1373.1999.d01-38.x     Document Type: Conference Paper

References (14)

1. Fujiki H, Komori A, Suganuma M. Chemoprevention of cancer. In: Bowden GT, Fischer SM, Eds. Comprehensive Toxicology. London: Pergamon Elsevier Sci, 12:pp453-471, 1997.
2. Imai K, Suga K, Nakachi K. Cancer-preventive effects of drinking green tea among a Japanese population. Prev Med 26:769-775, 1997.
3. 3H] (-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis 19:1771-1776, 1998.
4. Okabe S, Suganuma M, Hayashi M, Sueoka E, Komori A, Fujiki H. Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols. Jpn J Cancer Res 88:639-643, 1997.
5. Taniguchi S, Fujiki H, Kobayashi H, Go H, Miyado K, Sadano H, Shimokawa R. Effect of (-)-epigallocatechin gallate, the main constituent of green tea, on lung metastasis with mouse B16 melanoma cell lines. Cancer Lett 65:51-54, 1992.
6. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614, 1992.
7. Hescheler J, Mieskes G, Ruegg JC, Takai A, Trautwein W. Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes. Pflugers Arch 412:248-252, 1988.
8. Yoshizawa S, Horiuchi T, Suganuma M, Nishiwaki S, Yatsunami J, Okabe S, Okuda T, Muto Y, Frenkel K, Troll W, Fujiki H. Penta-O-galloyl-B-D-glucose and (-)-epigallocatechin gallate cancer preventive agents. In: Huang MT, Ho CT, Lee CY, Eds. Phenolic Compounds in Food and Their Prevention. ACS Symposium Series 507:pp316-325, 1992.
9. Kitano K, Nam KY, Kimura S, Fujiki H, Imanishi Y. Sealing effects of (-)-epigallocatechin gallate on protein kinase C and protein phosphatase 2A. Biophys Chem 65:157-164, 1997.
10. Suganuma M, Okabe S, Sueoka E, Iida N, Komori A, Kim SJ, Fujiki H. A new process of cancer prevention mediated through inhibition of tumor necrosis factor α expression. Cancer Res 56:3711-3715, 1996.
11. Imai K, Nakachi K. Cross-sectional study of effects of drinking green tea on cardiovascular and liver diseases. BMJ 310:693-696, 1995.
12. Nakachi K, Suemasu K, Suga K, Takeo T, Imai K, Higashi Y. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res 89:254-261, 1998.
13. Matsushima Y, Hayashi S, Tashibana M. Spontaneously hyperlipidemic (SHL) mice: Japanese wild mice with apolipoprotein E deficiency. Mamm. Genome: (in press), 1999.
14. Aggarwal BB, Natarajan K. Tumor necrosis factors: Developments during the last decade. Eur Cytokine Netw 7:93-124, 1996.