메뉴 건너뛰기




Volumn 67, Issue 4, 1999, Pages 1853-1859

Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN;

EID: 0033066901     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/.67.4.1853-1859.1999     Document Type: Article
Times cited : (112)

References (34)
  • 1
    • 0028171066 scopus 로고
    • The cytoplasmic domain of the diphtheria toxin receptor (HB-EGF precursor) is not required for receptor-mediated endocytosis
    • Almond, B. D., and L. Eidels. 1994. The cytoplasmic domain of the diphtheria toxin receptor (HB-EGF precursor) is not required for receptor-mediated endocytosis. J. Biol. Chem. 269:26635-26641.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26635-26641
    • Almond, B.D.1    Eidels, L.2
  • 2
    • 0028072074 scopus 로고
    • Fusions of anthrax train lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells
    • Arora, N., and S. H. Leppla. 1994. Fusions of anthrax train lethal factor with Shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells. Infect. Immun. 62:4955-4961.
    • (1994) Infect. Immun. , vol.62 , pp. 4955-4961
    • Arora, N.1    Leppla, S.H.2
  • 3
    • 0032539990 scopus 로고    scopus 로고
    • Identification of residues lining the anthrax protective antigen channel
    • Benson, E. L., P. D. Huynh, A. Finkelstein, and R. J. Collier. 1998. Identification of residues lining the anthrax protective antigen channel. Biochemistry 37:3941-3948.
    • (1998) Biochemistry , vol.37 , pp. 3941-3948
    • Benson, E.L.1    Huynh, P.D.2    Finkelstein, A.3    Collier, R.J.4
  • 4
    • 0025201667 scopus 로고
    • Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Effects on macroscopic conductance
    • Blaustein, R. O., and A. Finkelstein. 1990. Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Effects on macroscopic conductance. J. Gen. Physiol. 96:905-919.
    • (1990) J. Gen. Physiol. , vol.96 , pp. 905-919
    • Blaustein, R.O.1    Finkelstein, A.2
  • 5
    • 0024523836 scopus 로고
    • Anthrax toxin: Channel-forming activity of protective antigen in planar phospholipid bilayers
    • Blaustein, R. O., T. M. Koehler, R. J. Collier, and A. Finkelstein. 1989. Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers. Proc. Natl. Acad. Sci. USA 86:2209-2213.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2209-2213
    • Blaustein, R.O.1    Koehler, T.M.2    Collier, R.J.3    Finkelstein, A.4
  • 7
    • 0026044658 scopus 로고
    • Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells
    • Escuyer, V., and R. J. Collier. 1991. Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells. Infect. Immun. 59:3381-3386.
    • (1991) Infect. Immun. , vol.59 , pp. 3381-3386
    • Escuyer, V.1    Collier, R.J.2
  • 8
    • 0022891493 scopus 로고
    • Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
    • Friedlander, A. M. 1986. Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J. Biol. Chem. 261:7123-7126.
    • (1986) J. Biol. Chem. , vol.261 , pp. 7123-7126
    • Friedlander, A.M.1
  • 9
    • 0012550671 scopus 로고
    • Anthrax protective antigen receptor: Identification of a protective antigen binding protein by chemical cross-linking
    • B. Withholdt (ed.), Gustav Fischer, New York, N. Y.
    • Friedlander, A. M., and A. Raziuddin. 1992. Anthrax protective antigen receptor: identification of a protective antigen binding protein by chemical cross-linking, p. 365-366. In B. Withholdt (ed.), Bacterial protein toxins. Gustav Fischer, New York, N. Y.
    • (1992) Bacterial Protein Toxins , pp. 365-366
    • Friedlander, A.M.1    Raziuddin, A.2
  • 10
    • 0023932170 scopus 로고
    • Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin
    • Gordon, V. M., S. H. Leppla, and E. L. Hewlett. 1988. Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin. Infect. Immun. 56:1066-1069.
    • (1988) Infect. Immun. , vol.56 , pp. 1066-1069
    • Gordon, V.M.1    Leppla, S.H.2    Hewlett, E.L.3
  • 12
    • 0028088404 scopus 로고
    • Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
    • Klimpel, K. R., N. Arora, and S. H. Leppla. 1994. Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol. Microbiol. 13:1093-1100.
    • (1994) Mol. Microbiol. , vol.13 , pp. 1093-1100
    • Klimpel, K.R.1    Arora, N.2    Leppla, S.H.3
  • 13
    • 0026498189 scopus 로고
    • Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin
    • Klimpel, K. R., S. S. Molloy, G. Thomas, and S. H. Leppla. 1992. Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin. Proc. Natl. Acad. Sci. USA 89:10277-10281.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10277-10281
    • Klimpel, K.R.1    Molloy, S.S.2    Thomas, G.3    Leppla, S.H.4
  • 14
    • 0026690341 scopus 로고
    • The alpha 2-macroglobulin receptor/ low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A
    • Kounnas, M. Z., R. E. Morris, M. R. Thompson, D. J. FitzGerald, D. K. Strickland, and C. B. Saelinger. 1992. The alpha 2-macroglobulin receptor/ low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J. Biol. Chem. 267:12420-12423.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12420-12423
    • Kounnas, M.Z.1    Morris, R.E.2    Thompson, M.R.3    FitzGerald, D.J.4    Strickland, D.K.5    Saelinger, C.B.6
  • 15
    • 0000947082 scopus 로고
    • Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
    • Leppla, S. H. 1982. Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc. Natl. Acad. Sci. USA 79:3162-3166.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 3162-3166
    • Leppla, S.H.1
  • 16
    • 0002661972 scopus 로고
    • The anthrax toxin complex
    • J. E. Alouf and J. H. Freer (ed.), Academic Press, London, United Kingdom
    • Leppla, S. H. 1991. The anthrax toxin complex, p. 277-302. In J. E. Alouf and J. H. Freer (ed.), Sourcebook of bacterial protein toxins. Academic Press, London, United Kingdom.
    • (1991) Sourcebook of Bacterial Protein Toxins , pp. 277-302
    • Leppla, S.H.1
  • 18
    • 0001825875 scopus 로고
    • Proteolytic activation of anthrax toxin bound to cellular receptors
    • F. Fehrenbach, J. E. Alouf, P. Falmagne, W. Goebel, J. Jeljaszewicz, D. Jurgen, and R. Rappuoli (ed.), Gustav Fischer, New York, N.Y.
    • Leppla, S. H., A. M. Friedlander, and E. Cora. 1988. Proteolytic activation of anthrax toxin bound to cellular receptors, p. 111-112. In F. Fehrenbach, J. E. Alouf, P. Falmagne, W. Goebel, J. Jeljaszewicz, D. Jurgen, and R. Rappuoli (ed.), Bacterial protein toxins. Gustav Fischer, New York, N.Y.
    • (1988) Bacterial Protein Toxins , pp. 111-112
    • Leppla, S.H.1    Friedlander, A.M.2    Cora, E.3
  • 19
    • 0027443262 scopus 로고
    • pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen
    • Milne, J. C., and R. J. Collier. 1993. pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen. Mol. Microbiol. 10:647-653.
    • (1993) Mol. Microbiol. , vol.10 , pp. 647-653
    • Milne, J.C.1    Collier, R.J.2
  • 20
    • 0028018856 scopus 로고
    • Anthrax protective antigen forms oligomers during intoxication of mammalian cells
    • Milne, J. C., D. Furlong, P. C. Hanna, J. S. Wall, and R. J. Collier. 1994. Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J. Biol. Chem. 269:20607-20612.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20607-20612
    • Milne, J.C.1    Furlong, D.2    Hanna, P.C.3    Wall, J.S.4    Collier, R.J.5
  • 21
    • 0026775916 scopus 로고
    • Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
    • Molloy, S. S., P. A. Bresnahan, S. H. Leppla, K. R. Klimpel, and G. Thomas. 1992. Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J. Biol. Chem. 267:16396-16402.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16396-16402
    • Molloy, S.S.1    Bresnahan, P.A.2    Leppla, S.H.3    Klimpel, K.R.4    Thomas, G.5
  • 22
    • 0028107656 scopus 로고
    • Intracellular trafficking and activation of the furin proprotein convertase: Localization to the TGN and recycling from the cell surface
    • Molloy, S. S., L. Thomas, J. K. VanSlyke, P. E. Stenberg, and G. Thomas. 1994. Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J. 13:18-33.
    • (1994) EMBO J. , vol.13 , pp. 18-33
    • Molloy, S.S.1    Thomas, L.2    VanSlyke, J.K.3    Stenberg, P.E.4    Thomas, G.5
  • 23
    • 0026747170 scopus 로고
    • Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
    • Naglich, J. G., J. E. Metherall, D. W. Russell, and L. Eidels. 1992. Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 69:1051-1061.
    • (1992) Cell , vol.69 , pp. 1051-1061
    • Naglich, J.G.1    Metherall, J.E.2    Russell, D.W.3    Eidels, L.4
  • 24
    • 0026794750 scopus 로고
    • Functional characterization of protease-treated Bacillus anthracis protective antigen
    • Novak, J. M., M. P. Stein, S. F. Little, S. H. Leppla, and A. M. Friedlander. 1992. Functional characterization of protease-treated Bacillus anthracis protective antigen. J. Biol. Chem. 267:17186-17193.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17186-17193
    • Novak, J.M.1    Stein, M.P.2    Little, S.F.3    Leppla, S.H.4    Friedlander, A.M.5
  • 26
    • 0026050285 scopus 로고
    • Contribution of individual toxin components to virulence of Bacillus anthracis
    • Pezard, C., P. Berche, and M. Mock. 1991. Contribution of individual toxin components to virulence of Bacillus anthracis. Infect. Immun. 59:3472-3477.
    • (1991) Infect. Immun. , vol.59 , pp. 3472-3477
    • Pezard, C.1    Berche, P.2    Mock, M.3
  • 27
    • 0029055938 scopus 로고
    • Antigen presentation mediated by recycling of surface HLA-DR molecules
    • Pinet, V., M. Vergelli, R. Martin, O. Bakke, and E. O. Long. 1995. Antigen presentation mediated by recycling of surface HLA-DR molecules. Nature 375:603-606.
    • (1995) Nature , vol.375 , pp. 603-606
    • Pinet, V.1    Vergelli, M.2    Martin, R.3    Bakke, O.4    Long, E.O.5
  • 28
    • 0025747514 scopus 로고
    • Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis
    • Quinn, C. P., Y. Singh, K. R. Klimpel, and S. H. Leppla. 1991. Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis. J. Biol. Chem. 266:20124-20130.
    • (1991) J. Biol. Chem. , vol.266 , pp. 20124-20130
    • Quinn, C.P.1    Singh, Y.2    Klimpel, K.R.3    Leppla, S.H.4
  • 29
    • 0024837128 scopus 로고
    • A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo
    • Singh, Y., V. K. Chaudhary, and S. H. Leppla. 1989. A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J. Biol. Chem. 264:19103-19107.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19103-19107
    • Singh, Y.1    Chaudhary, V.K.2    Leppla, S.H.3
  • 30
    • 0028172211 scopus 로고
    • The chymotrypsin-sensitive site, FFD315, in anthrax toxin protective antigen is required for translocation of lethal factor
    • Singh, Y., K. R. Klimpel, N. Arora, M. Sharma, and S. H. Leppla. 1994. The chymotrypsin-sensitive site, FFD315, in anthrax toxin protective antigen is required for translocation of lethal factor. J. Biol. Chem. 269:29039-29046.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29039-29046
    • Singh, Y.1    Klimpel, K.R.2    Arora, N.3    Sharma, M.4    Leppla, S.H.5
  • 31
    • 0025858389 scopus 로고
    • The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity
    • Singh, Y., K. R. Klimpel, C. P. Quinn, V. K. Chaudhary, and S. H. Leppla. 1991. The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity. J. Biol. Chem. 266:15493-15497.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15493-15497
    • Singh, Y.1    Klimpel, K.R.2    Quinn, C.P.3    Chaudhary, V.K.4    Leppla, S.H.5
  • 32
    • 20444435374 scopus 로고
    • Purification of the third factor of anthrax toxin
    • Smith, H., and J. L. Stanley. 1962. Purification of the third factor of anthrax toxin. J. Gen. Microbiol. 29:517-521.
    • (1962) J. Gen. Microbiol. , vol.29 , pp. 517-521
    • Smith, H.1    Stanley, J.L.2
  • 33
    • 0032581369 scopus 로고    scopus 로고
    • Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
    • Vitale, G., R. Pellizzari, C. Recchi, G. Napolitani, M. Mock, and C. Montecucco. 1998. Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages. Biochem. Biophys. Res. Commun. 248:706-711.
    • (1998) Biochem. Biophys. Res. Commun. , vol.248 , pp. 706-711
    • Vitale, G.1    Pellizzari, R.2    Recchi, C.3    Napolitani, G.4    Mock, M.5    Montecucco, C.6
  • 34
    • 0032506245 scopus 로고    scopus 로고
    • Characterization of membrane translocation by anthrax protective antigen
    • Wesche, J., J. L. Elliott, P. O. Falnes, S. Olsnes, and R. J. Collier. 1998. Characterization of membrane translocation by anthrax protective antigen. Biochemistry 37:15737-15746.
    • (1998) Biochemistry , vol.37 , pp. 15737-15746
    • Wesche, J.1    Elliott, J.L.2    Falnes, P.O.3    Olsnes, S.4    Collier, R.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.