New approaches to antimutagenesis

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 18, Issue 2, 1999, Pages 95-101

  Heddle, John A ^a   Moody, Jennifer ^b   Thompson, Lilian U ^a,c   Torous, Dorothea K ^d   Trentin, Grace ^a,e  

^a YORK UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d LITRON LABORATORIES   (United States)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Development; Diet; Micronuclei; Spontaneous mutation

Indexed keywords

ANTIMUTAGENIC AGENT;

ANIMAL CELL; CARCINOGENESIS; CHROMOSOME DAMAGE; DIETARY INTAKE; MICRONUCLEUS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOMATIC MUTATION; SPONTANEOUS MUTATION;

ANIMALS; ANTIMUTAGENIC AGENTS; DRUG ANTAGONISM; HUMANS; MICE; MUTAGENESIS; MUTAGENS;

ANIMALIA;

EID: 0033066867     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (25)

1. Fiala ES, Bobotas G, Kulakis C, Wattenberg LW, Weisburger JH. The effect of disulfiram and related compounds on the metabolism in vivo of the colon carcinogen, 1,2 dimethylhydrazine. Biochem Pharmacol 1977; 26:1763-1768.
2. Jones IM, Burkhart-Shultz K, Carrano AV. A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes. Mutat Res 1985; 147:97-105.
3. Mailing HV, Burkhart JG. Use of φ X174 as a shuttle vector for the study of in vivo mammalian mutagenesis. Mutat Res 1989; 212:11-21X.
4. Kohler SW, Provost GS, Fieck A, Kretz PL, Bullock WO, Sorge JA, Putman DL, Short JM. Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice. Proc Natl Acad Sci USA 1991; 88:7958-7962.
5. Gossen JA, de Leeuw WJ, Tan CH, Zwarthoff EC, Berends F, Lohman PH, Knook DL, Vijg J. Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo. Proc Natl Acad Sci USA 1989; 86:7971-7975.
6. Gossen JA, Molijn AC, Douglas GR, Vijg J. Application of galactose-sensitive E. coli strains as selective hosts for LacZ plasmids. Nucl Acids Res 1992; 20:3254.
7. Zhang XB, Urlando C, Tao KS, Heddle JA. Factors affecting somatic mutation frequencies in vivo. Mutat Res 1995; 338:189-201.
8. Drake JW, Charlesworth B, Charlesworth D,Crow JF. Rates of spontaneous mutation. Genetics 1998; 148:1667-1686.
9. Skopek TR, Kort KL, Marino DR. Relative sensitivity of the endogenous hprt gene and locI transgene in ENU-treated Big Blue B6C3F1 mice. Environ Mol Mutagen 1995; 26:9-15.
10. Heddle JA. The use of transgenic animals in research. Environ Mol Mutagen 1998; in press.
11. Russell LB, Russell WL. Spontaneous mutations recovered as mosaics in the mouse specific-locus test. Proc Natl Acad Sci USA 1996; 93:13072-13077.
12. Jakubczak JL, Merlino G, French JE, Muller WJ, Paul B, Adhya S, Garges S. Analysis of genetic instability during mammary-tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage-lambda trans-gene target. Proc Natl Acad Sci USA 1996; 93:9073-9078.
13. Klein CB, Kargacin B, Su L, Cosentino S, Snow ET, Costa M. Metal mutagenesis in transgenic Chinese hamster cell lines. Environ Health Perspect 1994; 102:63-67.
14. Grawe J, Nusse M, Adler DD. Quantitative and qualitative studies of micronucleus induction in mouse erythrocytes using flow-cytometry. 1. Measurement of micronucleus induction in peripheral-blood polychromatic erythrocytes by chemicals with known and suspected genotoxicity. Mutagenesis 1997; 12:1-8.
15. Hayashi M, Norppa H, Sofuni T, Ishidate M. Mouse bone marrow micronucleus test using flow cytometry. Mutagenesis 1992; 7:251-256.
16. Tometsko AM, Dertinger SD, Torous DK. Analysis of micronucleated cells by flow-cytometry. 4. Kinetic-analysis of cytogenetic damage in blood. Mutat Res 1995; 334:9-18.
17. MacGregor JT, Wehr CM, Gould DH. Clastogen-induced micronuclei in peripheral blood erythrocytes: the basis of an improved micronucleus test. Environ Mutagen 1980; 2:509-514.
18. Dertinger SD, Torous DK, Tometsko KR, Flow cytometric analysis of micronucleated reticulocytes in mouse bone-marrow. Mutat Res 1997; 390:257-262.
19. Salamone MF, Heddle JA. The bone marrow micronucleus assay: rationale for a revised protocol. In: de Serres FJ, ed. New York: Plenum Publishing Corporation, 1983: 111-149.
20. Cairns J. Mutation selection and the natural history of cancer. Nature 1975; 255:197-200.
21. Heddle JA, Cosentino L, Dawod G, Swiger RR, Paashuis-Lew Y. Why do stem cells exist? Environ Mol Mutagen 1996; 28:334-341.
22. Paashuis-Lew Y, Zhang XB, Heddle JA. On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice. Mutat Res 1997; 373:277-284.
23. Armstrong B, Doll R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. Int J Cancer 1975; 15:617-631.
24. Heddle JA. Mutant manifestation: the time factor in somatic mutagenesis. Mutagenesis 1998, in press.
25. Haenszel W, Berg JW, Segi M, Kurihara M, Locke FB. Large-bowel cancer in Hawaiian Japanese. J Natl Cancer Inst 1973; 51:1765-1779.