Lysis via the lectin pathway of complement activation: Minireview and lectin pathway enhancement of endotoxin-initiated hemolysis

Immunopharmacology

Volumn 42, Issue 1-3, 1999, Pages 81-90

  Zhang, Yonghong ^a   Suankratay, Chusana ^a   Zhang, Xiao Hui ^a   Lint, Thomas F ^a   Gewurz, Henry ^a  

^a RUSH MEDICAL COLLEGE   (United States)

Author keywords

Complement; Endotoxin; Lectin pathway; Mannan binding lectin

Indexed keywords

C REACTIVE PROTEIN; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C4B; COMPLEMENT FACTOR H; EGTAZIC ACID; ENDOTOXIN; IMMUNOGLOBULIN G; LECTIN; MANNAN;

ANIMAL CELL; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOLYSIS; ERYTHROCYTE; GUINEA PIG; HEMOLYSIS; HUMAN; HUMAN CELL; IMMUNE COMPLEX DEPOSITION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0033066157     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(99)00029-6     Document Type: Conference Paper

References (22)

1. Cooper N.R., Morrison D.C. Binding and activation of the first component of human complement by the lipid A region of lipopolysaccharides. J. Immunol. 120:1978;1862-1868.
2. Gewurz H., Ying S.C., Jiang H., Lint T.F. Nonimmune activation of the classical complement pathway. Behring Inst. Mitt. 93:1993;138-147.
3. Ikeda K., Sannoh T., Kawasaki N., Kawasaki T., Yamashina I. Serum lectin with known structure activates complement through the classical pathway. J. Biol. Chem. 262:1987;7451-7454.
4. Ji Y.H., Matsushita M., Okada H., Fujita T., Kawakami M. The C4 and C2 but not C1 components of complement are responsible for the complement activation triggered by the Ra-reactive factor. J. Immunol. 141:1988;4271-4275.
5. Ji Y.H., Fujita T., Hatsuse H., Takahashi A., Matsushita M., Kawakami M. Activation of the C4 and C2 components of complement by a proteinase in serum bactericidal factor, Ra reactive factor. J. Immunol. 150:1993;571-578.
6. Kawasaki N., Kawasaki T., Yamashina I. A serum lectin (mannan-binding protein) has complement-dependent bactericidal activity. J. Biochem. (Tokyo). 106:1989;483-489.
7. Loos M., Bitter-Suermann D., Dierich M. Interaction of the first (C1), the second (C2) and the fourth (C4) component of complement with different preparations of bacterial lipopolysaccharides and with lipid A. J. Immunol. 112:1974;935-940.
8. Matsushita M. The lectin pathway of the complement system. Microbiol. Immunol. 40:1996;887-893.
9. Matsushita M., Fujita T. Cleavage of the third component of complement (C3) by mannose-binding protein-associated serine protease (MASP) with subsequent complement activation. Immunobiology. 194:1995;443-448.
10. Matsushita M., Endo Y., Fujita T. MASP1 (MBL-associated serine protease 1). Immunobiology. 199:1998;340-347.
11. Morrison D.C., Kline L.F. Activation of the classical and properdin pathways of complement by bacterial lipopolysaccharides (LPS). J. Immunol. 118:1977;362-368.
12. Sato T., Endo Y., Matsushita M., Fujita T. Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein. Int. Immunol. 6:1994;665-669.
13. Schweinle J.E., Ezekowitz R.A., Tenner A.J., Kuhlman M., Joiner K.A. Human mannose-binding protein activates the alternative complement pathway and enhances serum bactericidal activity on a mannose-rich isolate of Salmonella. J. Clin. Invest. 84:1989;1821-1829.
14. Suankratay C., Mold C., Zhang Y., Jones D.R., Lint T.F., Gewurz H. Complement-dependent hemolysis in human serum via the lectin pathway: regulation by C4bp, factor H and immunoglobulins. Mol. Immunol. 35:1998;390. (abstract).
15. Suankratay C., Mold C., Zhang Y., Potempa L.A., Lint T.F., Gewurz H. Complement regulation in innate immunity and the acute-phase response: inhibition of mannan-binding lectin-initiated complement cytolysis by C-reactive protein (CRP). Clin. Exp. Immunol. 113:1998;353-359.
16. Suankratay C., Zhang X.H., Zhang Y., Lint T.F., Gewurz H. Requirement for the alternative pathway as well as C4 and C2 in complement-dependent hemolysis via the lectin pathway. J. Immunol. 160:1998;3006-3013.
17. Suankratay, C., Mold, C., Zhang, Y., Lint, T.F., Gewurz, H., 1999. Mechanism of complement-dependent hemolysis via the lectin pathway: role of the complement regulatory proteins. Clin. Exp. Immunol., in press.
18. Tan S.M., Chung M.C., Kon O.L., Thiel S., Lee S.H., Lu J. Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a C1s-like serine protease. Biochem. J. 319:1996;329-332.
19. Thiel S., Vorup-Jensen T., Stover C.M., Schwaeble W., Laursen S.B., Poulsen K., Willis A.C., Eggleton P., Hansen S., Holmskov U., Reid K.B., Jensenius J.C. A second serine protease associated with mannan-binding lectin that activates complement. Nature. 386:1997;506-510.
20. Vorup-Jensen T., Jensenius J.C., Thiel S. MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology. 199:1998;348-357.
21. Vukajlovich S.W. Antibody-independent activation of the classical pathway of human serum complement by lipid A is restricted to re-chemotype lipopolysaccharide and purified lipid A. Infect. Immunol. 53:1986;480-485.
22. Zhang, Y., Suankratay, C., Jones, D.R., Zang, X.-H., Lint, T.F., Gewurz, H., 1999. Calcium dependent hemolysis via the lectin pathway of complement activation in the guinea pig and other species. Immunology (in press).