Tracheal ligation and mechanical ventilation do not improve the antioxidant enzyme status in the lamb model of congenital diaphragmatic hernia

Journal of Pediatric Surgery

Volumn 34, Issue 2, 1999, Pages 270-272

  Kapur, Pierina ^a   Holm, Bruce A ^a   Irish, Michael S ^a   Patel, Alka ^a   Glick, Philip L ^a,b  

^a UNIVERSITY AT BUFFALO   (United States)

^b CHILDREN S HOSPITAL OF BUFFALO   (United States)

Author keywords

Antioxidant enzyme; Catalase; Congenital diaphragmatic hernia; Glutathione peroxidase; Mechanical ventilation; Superoxide dismutase; Tracheal ligation

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTIFICIAL VENTILATION; CONFERENCE PAPER; CONGENITAL DIAPHRAGM HERNIA; ENZYME ACTIVITY; ENZYME SYNTHESIS; FETUS; FETUS LUNG MATURATION; LAMB; LUNG FUNCTION; NONHUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; SURGICAL TECHNIQUE; TRACHEA SURGERY;

EID: 0033065933     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3468(99)90188-4     Document Type: Conference Paper

References (17)

1. Frank L, Bucher JR, Roberts RJ: Oxygen toxicity in neonatal and adult animals of various species. J Appl Physiol 45:669-704, 1978
2. Fridovich I, Freeman B: Antioxidant defenses in the lung. Ann Rev Physiol 48:693-702, 1986
3. Transwell A, Freeman B: Pulmonary antioxidant maturation in the fetal and neonatal rat. 1. Developmental profiles. Pediatr Res 18:584-587, 1984
4. Keeney SE, Cress SE, Brown SE, et al: The effect of hyperoxic exposure on antioxidant enzyme activities of alveolar type II cells in neonatal and adult rats. Pediatr Res 31:441-444, 1992
5. Frank L, Sosiznko IRS: Development of lung antioxidant enzymes in late gestation: possible implications of the prematurely born infant. J Pediatr 110:9-14, 1987
6. Glick PL, Stannard VA, Leach CL, et al: Pathophysiology of congenital diaphragmatic hernia II: The fetal lamb CDH model is surfactant deficient. J Pediatr Surg 27:382-387; discussion 387-388, 1992
7. Glick PL, Leach CL, Besner GE, et al: Pathophysiology of congenital diaphragmatic hernia. III: Exogenous surfactant therapy for the high-risk neonate with CDH. J Pediatr Surg 27:866-869, 1992
8. Alcorn D, Adamson TM, Lambert TF, et al: Morphological effects of chronic tracheal ligation and drainage in the fetal lamb lung. J Anat 123:649-660, 1977
9. Carmel JA, Friedman F, Adams FH: Fetal tracheal ligation and lung development. Am J Dis Child 109:452-456, 1965
10. Nardo L, Hooper S, Harding R: Lung hypoplasia can be reversed by short-term obstruction of the trachea in fetal sheep. Pediatr Res 38:690-696, 1995
11. Irish MS, O'Toole SJ, Sharma A, et al: Ventilatory stratch enhances surfactant synthesis in the fetal lamb model of congenital diaphragmatic hernia. American Thoracic Society, San Francisco, CA. Am J Respir Crit Care Med 28:1997
12. O'Toole SJ, Sharma A, Karamanoukian HL, et al: Tracheal ligation does not correct surfactant deficiency associated with congenital diaphragmatic hernia. J Pediatr Surg 31:546-550, 1996
13. Luck H: Catalase, in Bergmeyer H (ed): Methods of Enzymatic Analysis. New York, NY, Academic, 1963, pp 885-888
14. Beutler E: Red Cell Metabolism: A Manual of Biochemical Methods. New York, NY, Grune and Stratton, 1975, pp 71-75
15. O'Toole SJ, Karamanoukian HL, Irish MS, et al: Tracheal ligation: The dark side of in utero CDH treatment. J Pediatr Surg 32:407-410, 1997
16. Sluiter W, Bos AP, Siluin F, et al: Nitrofen-induced diaphragmatic hernias in rats: Pulmonary antioxidant enzyme activities. Pediatr Res 32:394-398, 1992
17. Yam J, Frank L, Roberts RJ: Oxygen toxicity: Comparison of lung biochemical responses in neonatal and adult rats. Pediatr Res 12:115-119, 1978