Distinct responses of the herpes simplex virus and varicella zoster virus immediate early promoters to the cellular transcription factors Brn-3a and Brn-3b

International Journal of Biochemistry and Cell Biology

Volumn 31, Issue 3-4, 1999, Pages 451-461

  Brownlees, Janet ^a   Gough, Gerald ^b   Thomas, Suzanne ^a   Watts, Paul ^b   Cohen, Jeffrey ^c   Coffin, Robert ^a   Latchman, David S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Sect Clin and Exp Neuropsychol   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMEDIATE EARLY PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; EXPRESSION VECTOR; FIBROBLAST; HERPES SIMPLEX VIRUS; LATENT VIRUS INFECTION; NONHUMAN; VARICELLA ZOSTER VIRUS; VIRUS LATENCY; VIRUS REACTIVATION;

CELLS, CULTURED; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA PRIMERS; DNA-BINDING PROTEINS; GENES, IMMEDIATE-EARLY; HERPESVIRUS 3, HUMAN; HUMANS; MODELS, GENETIC; PLASMIDS; PROMOTER REGIONS (GENETICS); SIMPLEXVIRUS; TRANSCRIPTION FACTOR BRN-3; TRANSCRIPTION FACTOR BRN-3A; TRANSCRIPTION FACTOR BRN-3B; TRANSCRIPTION FACTORS; TRANSFECTION;

HERPES; HUMAN HERPESVIRUS 3; SIMPLEXVIRUS; STAPHYLOCOCCUS PHAGE 3A;

EID: 0033064660     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(98)00151-4     Document Type: Article

References (40)

1. Roizman B., Sears A.E. An inquiry into the mechanisms of herpes simplex virus latency. Ann. Rev. Microbiol. 41:1987;543-571.
2. Latchman D.S. Molecular biology of herpes simplex virus latency. Int. J. Exp. Pathol. 71:1990;133-141.
3. Meier J.L., Straus S.E. Comparative biology of latent varicella zoster and herpes simplex virus infections. J. Infect. Dis. 166:1992;S13-23.
4. Meier J.L., Holman R.P., Croen K.D., Smialek J.E., Straus S.E. Varicella zoster virus transcription in human trigeminal ganglia. Virology. 193:1993;193-200.
5. Lungu O., Annuziato P.W., Gershon A., Staugaitis S.M., Josefson D., LaRussa P., Silverstein S.J. Reactivated and latent varicella zoster virus in human dorsal root ganglia. Proc. Natl. Acad. Sci. USA. 92:1995;10980-10984.
6. Verrijzer C.P., van der Vliet P.C. POU domian transcription factors. Biochim. Biophys. Acta. 1173:1993;1-21.
7. Wegner M., Drolet D.W., Rosenfeld M.G. POU-domain proteins: structure and function of developmental regulators. Curr. Opin. Cell Biol. 5:1993;488-498.
8. Lillycrop K.A., Latchman D.S. Alternative splicing of the Oct-2 transcription factor is differentialy regulated in B-cells and neuronal cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters. J. Biol. Chem. 267:1992;24960-24966.
9. Lillycrop K.A., Dawson S.J., Estridge J.K., Gerster T., Matthias P., Latchman D.S. Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependant upon an inhibitory region at the N-terminus of the protein. Mol. Cell. Biol. 14:1994;7633-7642.
10. Lillycrop K.A., Estridge J.K., Latchman D.S. The octamer binding protein oct-2 inhibits transactivation of the herpes simplex virus immediate early genes by the virion protein Vmw65. Virology. 196:1993;888-891.
11. Hatzopoulos A.K., Stoykova A.S., Erselius J.R., Goulding M., Newman T., Gruss P. Structure and expression of the mouse Oct-2a and Oct-2b, two differentially spliced products of the same gene. Development. 109:1990;349-362.
12. Lillycrop K.A., Dent C.L., Wheatley S.C., Beech M.N., Ninkina N.N., Wood J.N., Latchman D.S. The octamer binding protein Oct-2 represses HSV immediate early genes in cell lines derived from latently infectable sensory neurons. Neuron. 7:1991;381-390.
13. Stoykova A.S., Steiner S., Erselius J.R., Hatzopoulos A.K., Grass P. Mini-Oct and Oct-2c: two novel functionally diverse murine Oct-2 products are differentialy expressed in the CNS. Neuron. 841:1992;541-558.
14. Croen K.D., Ostrove J.M., Dragovic L.J., Smialek J.E., Straus S.E. Latent herpes simplex virus in human trigeminal ganglia: detection of an immediate early gene anti-sense transcript by in situ hybridization. New Engl. J. Med. 317:1987;1427-1432.
15. Stevens J.G., Wagner E.K., Devi-Rao G.B., Cook M.L., Feldman L.T. RNA complementary to a herpes virus alpha gene mRNA is prominent in latently infected neurons. Science. 235:1987;1056-1059.
16. Patel Y.S., Gough G., Coffin R.S., Thomas S., Cohen J.I., Latchman D.S. Cell type specific repression of the variella zoster virus immediate early gene 62 promoter by the cellular Oct-2 transcription factor. Biochim. Biophys. Acta. 1397:1998;268-274.
17. Moriuchi H., Moriuchi M., Cohen J.I. Proteins and cis-acting elements associated with transactivation of the varicella zoster virus (VZV) immediate early gene 62 promoter by VZV open reading frame 10 protein. J. Virol. 69:1995;4693-4701.
18. Gerrero M.R., McEvilly R.J., Tuner E., Lin C.R., O'Connell S., Jenne K.J., Hobbs M.V., Rosenfeld M.G. Brn-3.0: a POU domain protein expressed in the sensory immune and endocrine systems that functions on elements distinct from known octamer motifs. Proc. Natl. Acad. Sci. USA. 90:1993;10841-10845.
19. Lillycrop K.A., Budhram-Mahadeo V.S., Lakin N.D., Terrenghi G., Wood J.N., Polak J.M., Latchman D.S. A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells. Nucleic Acids Res. 20:1992;5093-5096.
20. Lillycrop K.A., Liu Y.Z., Theil T., Moroy T., Latchman D.S. Activation of the herpes simplex virus immediate-early gene promoters by neuronally expressed POU family transcription factors. Biochem. J. 307:1995;581-584.
21. Budhram-Mahadeo V.S., Morris P.J., Lakin N.D., Theil T., Ching G.Y., Lillycrop K.A., Möröy T., Liem R.K.H., Latchman D.S. Activation of the α-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein. J. Biol. Chem. 270:1995;2853-2858.
22. Smith M.D., Dawson S.J., Latchman D.S. The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Mol. Cell. Biol. 17:1997;345-354.
23. Smith M.D., Morris P.J., Dawson P.J., Schwartz M.L., Schlaepfer W.W., Latchman D.S. Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor. J. Biol. Chem. 272:1997;21325-21333.
24. Lakin N.D., Morris P.J., Theil T., Sato T.N., Moroy T., Wilson M.C., Latchman D.S. Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor. J. Biol. Chem. 270:1995;15858-15863.
25. Perera L.P., Mosca J.D., Sadeghi-Zadeh M., Ruyechan W.T., Hay J. The varicella zoster virus immediate early protein IE62, can positively regulate its cognate promoter. Virology. 191:1992;346-354.
26. Gelman I.H., Silverstein S. Herpes simplex virus immediate early promoters are responsive to virus and cell trans acting factors. J. Virol. 61:1987;2286-2296.
27. Gelman I.H., Silverstein S. Dissection of immediate-early gene promoters from herpes simplex virus sequences that respond to virus transcriptional activators. J. Virol. 61:1987;3167-3172.
28. Macpherson I., Stoker M. Polyoma transformation of hamster cell clones: an investigation of the genetic factors affecting cell competence. Virology. 16:1962;147-151.
29. J.N. Wood, S.J. Bevan, P. Coote, P.M. Darn, P. Hogan, D.S. Latchman, C. Morrison, G. Rougon, M. Theveniau, S.C. Wheatley, Novel cell lines display the properties of nociceptive sensory neurons, in: Proceedings of the Royal Society of London Series B 241, 1990, pp. 187-194.
30. C.M. Gorman, High efficiency gene transfer into mammalian cells, in: D.M. Glover (Ed.), DNA Cloning, a Pratical Approach, IRL Press, 1985, pp. 143-190.
31. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of proteins utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
32. Abken H., Reifenrath B. A procedure to standardize CAT reporter gene assay. Nucleic Acids Res. 20:1992;3527.
33. Budhram-Mahadeo V.S., Theil T., Morris P.J., Lillycrop K.A., Möröy T., Latchman D.S. The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells. Nucleic Acids Res. 22:1994;3092-3098.
34. Morris P.J., Theil T., Ring C.J.A., Lillycrop K.A., Möröy T., Latchman D.S. The opposite and antagonistic effects of the closely related POU family transcription factors on the activity of a target promoter are dependent upon differences in the POU domain. Mol. Cell. Biol. 14:1994;6907-6914.
35. Theil T., McLean-Hunter S., Zornig M., Möröy T. Mouse Brn-3 family of POU transcription factors: a new amino terminal domain is crucial for the oncogenic activity of Brn-3A. Nucleic Acids Res. 21:1993;5921-5929.
36. Liu Y.-Z., Lee I.-K., Locke I., Dawson S.J., Latchman D.S. Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. Nucleic Acids Res. 26:1998;2464-2472.
37. Dawson S.J., Liu Y.-Z., Rodel B., Moroy T., Latchman D.S. The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements. Biochem. J. 314:1996;439-443.
38. Perry L.J., Rixon F.J., Everett R.D., Frame M.C., McGeogh D.J. Characterization of the IE110 gene of herpes simplex virus type 1. J. Gen Virol. 67:1986;2365-2380.
39. Morris P.J., Lakin N.D., Dawson S.J., Ryabanin A.E., Kilimann M.W., Wilson M.C., Latchman D.S. Differential regulation of genes encoding synaptic proteins by members of the Brn-3 sub family of POU transcription factors. Mol. Brain Res. 43:1997;279-285.
40. Milton N.G.N., Bessis A., Changeux J.P., Latchman D.S. The neuronal nicotinic acetylcholine receptor α2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c. J. Biol. Chem. 270:1995;15143-15147.