Development and validation of a sensitive solid-phase extraction and high-performance liquid chromatographic assay for the novel bio-reductive anti-tumor agent RH1 in human and mouse plasma

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 729, Issue 1-2, 1999, Pages 287-295

  Khan, Parveen ^a   Abbas, Sayara ^a   Hargreaves, Robert H J ^a   Caffrey, Robert ^a   Megram, Victoria ^a   McGown, Alan ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

RH1

Indexed keywords

2,5 DIAZIRIDINYL 3 (HYDROXYMETHYL) 6 METHYL 1,4 BENZOQUINONE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; NORMAL HUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; SOLID PHASE EXTRACTION;

EID: 0033064468     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00177-2     Document Type: Article

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