Use of microdilution panels with and without β-lactamase inhibitors as a phenotypic test for β-lactamase production among Escherichia coli, Klebsiella spp., Enterobacter spp., Citrobacter freundii, and Serratia marcescens

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 6, 1999, Pages 1393-1400

  Thomson, Kenneth S ^a   Sanders, Christine C ^a   Moland, Ellen Smith ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZTREONAM; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; CEFOTAXIME; CEFOTETAN; CEFOXITIN; CEFPODOXIME; CEFTAZIDIME; CEFTRIAXONE; CLAVULANIC ACID; SULBACTAM;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CITROBACTER FREUNDII; DILUTION; ENTEROBACTER; ENTEROBACTERIACEAE; ENZYME SYNTHESIS; ESCHERICHIA COLI; KLEBSIELLA; NONHUMAN; PRIORITY JOURNAL; SERRATIA MARCESCENS;

EID: 0033063978     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.6.1393     Document Type: Article

References (56)

1. Bauernfeind, A., Y. Chong, and S. Schweighart. 1989. Extended broadspectrum β-lactamase in Klebsiella pneumoniae including resistance to cephamycins. Infection 17:316-321.
2. Bauernfeind, A., H. Grimm, and S. Schweighart. 1990. A new plasmidic cefotaximase in a clinical isolate of Escherichia coli. Infection 18:294-298.
3. Bauernfeind, A., S. Schweighart, K. Dornbusch, and H. Giamarellou. 1990. A transferable cephamycinase (CMY-ase) in Klebsiella pneumoniae (K. pn.), abstr. 190, p. 118. In Program and abstracts of the 30th International Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
4. Bauernfeind, A., I. Stemplinger, R. Jungwirth, and H. Giamarellou. 1996. Characterization of the plasmidic β-lactamase CMY-2, which is responsible for cephamycin resistance. Antimicrob. Agents Chemother. 40:221-224.
5. cMY-1 gene and its relationship with other β-lactamases genes. Antimicrob. Agents Chemother. 40:1926-1930.
6. Bradford, P. A., C. Urban, N. Mariano, S. J. Projan, J. J. Rahal, and K. Bush. 1997. Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC β-lactamase, and the loss of an outer membrane protein. Antimicrob. Agents Chemother. 41:563-569.
7. Bret, L., C. Chanal, D. Sirot, R. Labia, and J. Sirot. 1996. Characterization of an inhibitor-resistant enzyme IRT-2 derived from TEM-2 β-lactamase produced by Proteus mirabilis strains. J. Antimicrob. Chemother. 38:183-191.
8. Brun-Buisson, C., P. Legrand, A. Philippon, F. Montravers, M. Ansquer, and J. Duval. 1987. Transferable enzymatic resistance to third-generation cephalosporins during nosocomial outbreak of multiresistant Klebsiella pneumoniae. Lancet ii:302-306.
9. Bush, K. 1996. Is it important to identify extended-spectrum beta-lactamase-producing isolates? Eur. J. Clin. Microbiol. Infect. Dis. 15:361-364.
10. Bush, K., G. A. Jacoby, and A. A. Medeiros. 1995. A functional classification scheme for β-lactamases and its correlation with molecular structure. Anti-microb. Agents Chemother. 39:1211-1233.
11. Casellas, J. M., and M. Goldberg. 1989. Incidence of strains producing extended spectrum β-lactamases in Argentina. Infection 17:434-436.
12. Coudron, P. E., E. S. Moland, and C. C. Sanders. 1997. Occurrence and detection of extended-spectrum β-lactamases in members of the family Enterobacteriaceae at a Veterans Medical Center: seek and you may find. J. Clin. Microbiol. 35:2593-2597.
13. Ehrhardt, A. F., C. C. Sanders, and E. S. Moland. 1999. Use of an isogenic Escherichia coli panel to design tests for discrimination of β-lactamase functional groups of Enterobacteriaceae. Antimicrob. Agents Chemother. 43:630-633.
14. Gazouli, M., L. S. Tzouvelekis, E. Prinarakis, V. Miriagau, and E. Tzelepi. 1996. Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 β-lactamase (LAT-2). Antimicrob. Agents Chemother. 40:1736-1740.
15. Henquell, C., D. Sirot, C. Chanal, C. DeChamps, P. Chatron, B. Lafeuille, P. Texier, J. Sirot, and R. Cluzel. 1994. Frequency of inhibitor-resistant TEM β-lactamases in Escherichia coli isolates from urinary tract infections in France. J. Antimicrob. Chemother. 34:707-714.
16. Horii, T., Y. Arakawa, M. Ohta, S. Ichiyama, R. Wacharotayankun, and N. Kato. 1993. Plasmid-mediated AmpC-type β-lactamase isolated from Klebsiella pneumoniae confers resistance to broad-spectrum β-lactams, including moxalactam. Antimicrob. Agents Chemother. 37:984-990.
17. Horii, T., Y. Arakawa, M. Ohta, T. Sugiyama, K. Wacharotayankun, H. Ito, and N. Kato. 1994. Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase. Gene 139: 93-98.
18. Jacoby, G. A., and I. Carreras. 1990. Activities of β-lactam antibiotics against Escherichia coli strains producing extended-spectrum β-lactamases. Antimicrob. Agents Chemother. 34:858-862.
19. Jacoby, G. A., and A. A. Medeiros. 1991. More extended-spectrum β-lactamases. Antimicrob. Agents Chemother. 35:1697-1704.
20. Jarlier, V., M.-H. Nicolas, G. Fournier, and A. Philippon. 1988. Extended broad-spectrum β-lactamases conferring transferable resistance to newer β-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev. Infect. Dis. 10:867-878.
21. Jenks, P. J., Y. M. Hu, F. Danel, S. Mehtar, and D. M. Livermore. 1995. Letter. J. Antimicrob. Chemother. 35:235-236.
22. Karas, J. A., D. G. Pillay, D. Muckart, and A. W. Sturm. 1996. Letter. J. Antimicrob. Chemother. 37:203-204.
23. Katsanis, G. P., J. Spargo, M. J. Ferraro, L. Sutton, and G. A. Jacoby. 1994. Detection of Klebsiella pneumoniae and Escherichia coli strains producing extended-spectrum β-lactamases. J. Clin. Microbiol. 32:691-696.
24. Legrand, P., G. Fournier, A. Buré, V. Jarlier, M. H. Nicolas, D. Decré, J. Duval, and A. Philippon. 1989. Detection of extended broad-spectrum beta-lactamases in Enlerobacteriaceae in four French hospitals. Eur. J. Clin. Microbiol. Infect. Dis. 8:527-529.
25. Leiza, M. G., J. C. Perez-Diaz, J. Ayala, J. M. Casellas, J. Martinez-Beltran, K. Bush, and F. Baquero. 1994. Gene sequence and biochemical characterization of FOX-1 from Klebsiella pneumoniae, a new AmpC-type plasmid-mediated β-lactamase with two molecular variants. Antimicrob. Agents Chemother. 38:2150-2157.
26. Lemozy, J., D. Sirot, C. Chanal, C. Huc, R. Labia, H. Dabernat, and J. Sirot. 1995. First characterization of inhibitor-resistant TEM (IRT) β-lactamases in Klebsiella pneumoniae strains. Antimicrob. Agents Chemother. 39:2580-2582.
27. Livermore, D. M. 1995. β-Lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:557-584.
28. Mabilat, C., and P. Courvalin. 1990. Development of "oligotyping" for characterization and molecular epidemiology of TEM β-lactamases in members of the family Enterobacteriaceae. Antimicrob. Agents Chemother. 34: 2210-2216.
29. Matthew, M. A., A. M. Harris, M. J. Marshall, and G. W. Ross. 1975. The use of analytical isoelectric focusing for detection and identification of β-lactamases. J. Gen. Microbiol. 88:169-178.
30. National Committee for Clinical Laboratory Standards. 1997. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A4. National Committee for Clinical Laboratory Standards, Villanova, Pa.
31. National Committee for Clinical Laboratory Standards. 1997. Performance standards for antimicrobial disk susceptibility tests. Approved standard M2-A6. National Committee for Clinical Laboratory Standards. Villanova, Pa.
32. National Committee for Clinical Laboratory Standards. 1999. Performance standards for antimicrobial susceptibility testing. Ninth informational supplement M100-S9. National Committee for Clinical Laboratory Standards, Wayne, Pa.
33. O'Callaghan, C. H., P. W. Muggleton, and G. W. Ross. 1969. Effects of β-lactamase from gram-negative organisms on cephalosporins and penicillins, p. 57-63. Antimicrob. Agents Chemother. 1968.
34. Pagani, L., F. Luzzaro, R. Migliavacca, M. G. Perilli, R. Daturi, G. Lombardi, C. Matti, E. Giacobone, and G. Amicosanle. 1997. Detection and characterization of extended spectrum β-lactamases in clinical isolates of Proteus mirabilis from North Italian hospitals, abstr. D-14, p. 85. In Program and abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
35. Papanicolaou, G. A., A. A. Medeiros, and G. A. Jacoby. 1990. Novel plasmidmedialed β-lactamase (MIR-1) conferring resistance to oxyimino- and α-methoxy β-lactams in clinical isolates of Klebsiella pneumoniae. Antimicrob. Agents Chemother. 34:2200-2209.
36. Payne, D. J., N. Woodford, and S. G. Amyes. 1992. Characterization of the plasmid mediated beta-lactamase BIL-1. J. Antimicrob. Chemother. 30:119-127.
37. Philippon, A., R. Labia, and G. A. Jacoby. 1989. Extended-spectrum β-lactamases. Antimicrob. Agents Chemother. 33:1131-1136.
38. Philippon, A., S. B. Redjeb, G. Fournier, and A. B. Hassen. 1989. Epidemiology of extended spectrum β-lactamases. Infection 17:347-354.
39. Pörnull, K. J., G. Rodrego, and K. Dornbusch. 1994. Production of a plasmid-mediated AmpC-like β-lactamase by a Klebsiella pneumoniae septicemia isolate. J. Antimicrob. Chemother. 34:943-954.
40. Prinarakis, E. E., V. Miriagou, E. Tzelepi, M. Gazouli, and L. S. Tzouvelekis. 1997. Emergence of an inhibitor-resistant β-lactamase (SHV-10) derived from an SHV-5 variant. Antimicrob. Agents Chemother. 41:838-840.
41. Pucci, M. J., J. Boice-Sowek, R. E. Kessler, and T. J. Dougherty. 1991. Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329. Antimicrob. Agents Chemother. 35:2312-2317.
42. Rice, L. B., E. C. Eckstein, J. DeVente, and D. M. Shlaes. 1996. Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical Center. Clin. Infect. Dis. 23:118-124.
43. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
44. Sanders, C. C., A. L. Barry, J. A. Washington, C. Shubert, E. S. Moland, M. M. Traczewski, C. Knapp, and R. Mulder. 1996. Detection of extended-spectrum-β-lactamase-producing members of the family Enterobacteriaceae with the Vitek ESBL test. J. Clin. Microbiol. 34:2997-3001.
45. Sanders, C. C., W. E. Sanders, Jr., and E. S. Moland. 1986. Characterization of β-lactamases in situ on polyacrylamide gels. Antimicrob. Agents Chemother. 30:951-952.
46. Sanders, C. C., K. S. Thomson, and P. A. Bradford. 1993. Problems with detection of β-lactam resistance among nonfastidious gram-negative bacilli. Infect. Dis. Clin. N. Am. 7:411-425.
47. Smith Moland, E., K. S. Thomson, and J. D. D. Pitoul. 1996. Detection of plasmid-encoded AmpC β-lactamase in E. coli and Klebsiella pneumoniae, abstr. A-41, p. 140. In Abstracts of the 96th General Meeting of the American Society for Microbiology. American Society for Microbiology, Washington, D.C.
48. Smith Moland, E., C. C. Sanders, and K. S. Thomson. 1998. Can results obtained with commercially available MicroScan microdilution panels serve as an indicator of β-lactamase production among Escherichia coli and Klebsiella isolates with hidden resistance to expanded-spectrum cephalosporins and aztreonam? J. Clin. Microbiol. 36:2575-2579.
49. Stapleton, P., P.-J. Wu, A. King, K. Shannon, G. French, and I. Phillips. 1995. Incidence and mechanisms of resistance to the combination of amoxicillin and clavulanic acid in Escherichia coli. Antimicrob. Agents Chemother. 39:2478-2483.
50. Thomson, C. J., and S. G. B. Amyes. 1992. TRC-1: emergence of a clavulanic acid-resistant TEM β-lactamase in a clinical strain. FEMS Microbiol. Lett. 91:113-118.
51. Thomson, K. S., A. M. Prevan, and C. C. Sanders. 1996. Novel plasmid-mediated β-lactamases in Enterobacteriaceae: emerging problems for new β-lactam antibiotics. Clin. Top. Infect. Dis. 16:151-163.
52. Thomson, K. S., and C. C. Sanders. 1992. Detection of extended-spectrum β-lactamases in members of the family Enterobacteriaceae: comparison of the double-disk and three-dimensional tests. Antimicrob. Agents Chemother. 36:1877-1882.
53. Thomson, K. S., and C. C. Sanders. 1997. A simple and reliable method to screen isolates of Escherichia coli and Klebsiella pneumoniae for the production of TEM- and SHV-derived extended-spectrum β-lactamases. Clin. Microbiol. Infect. 3:549-554.
54. Tzouvelekis, L. S., E. Tzelepi, A. F. Mentis, and A. Tsakris. 1993. Identification of a novel plasmid-mediated beta-lactamase with chromosomal cephalosporinase characteristics from Klebsiella pneumoniae. J. Antimicrob. Chemother. 31:645-654.
55. Vedel, G., A. Belaaouaj, L. Gilly, R. Labia, A. Philippen, P. Névot, and G. Paul. 1992. Clinical isolates of Escherichia coli producing TRI β-lactamases: novel TEM-enzymes conferring resistance to β-lactamase inhibitors. J. Antimicrob. Chemother. 30:449-462.
56. Vercauteren, E., P. Descheemaeker, M. Ieven, C. C. Sanders, and H. Goossens. 1997. Comparison of screening methods for detection of extended-spectrum β-lactamases and their prevalence among blood isolates of Escherichia coli and Klebsiella spp. in a Belgian teaching hospital. J. Clin. Microbiol. 35:2191-2197.