A fluorescence-based high throughput screen for the transporter associated with antigen processing

Journal of Biomolecular Screening

Volumn 4, Issue 2, 1999, Pages 87-91

  Blevitt, Jonathan M ^a   Früh, Klaus ^a   Glass, Charlie ^a   Jackson, Michael R ^a   Peterson, Per A ^a   Huang, Shaoming ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CONCANAVALIN A; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RHODAMINE; SEPHAROSE;

ANTIGEN PRESENTATION; ARTICLE; DNA SEQUENCE; DROSOPHILA MELANOGASTER; FILTRATION; FLUORESCENCE; IODINATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REPRODUCIBILITY; SCREENING; SIGNAL NOISE RATIO;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0033063909     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/108705719900400208     Document Type: Article

References (11)

1. Yewdell, J.W., Bennink, J.R. (1992). Cell biology of antigen processing and presentation to major histocompatibility complex class I molecule-restricted T lymphocytes. Adv. Immunol. 52:1-123.
2. Germain, R.N., Margulies, D.H. (1993). The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11:403-450.
3. Benham, A., Tulp, A., Neefjes, J. (1995). Synthesis and assembly of MHC-peptide complexes. Immunol. Today 16:359-362.
4. Bijlmakers, M.J., Ploegh, H.L. (1993). Putting together an MHC class I molecule. Curr. Opin. Immunol. 5:21-26.
5. DeMars, R., Chang, C.C., Shaw, S., Reitnauer, P.J., and Sondel, P.M. (1984). Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens. Hum. Immunol. 11:77-97.
6. Kleijmeer, M.J., Kelly, A., Geuze, H.J., Slot, J.W., Townsend, A., Trowsdale, J. (1992). Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi. Nature 357:342-344.
7. Spies, T., DeMars, R. (1991). Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter. Nature 351:323-324.
8. . de la Salle, H., Hanau, D., Fricker, D., Urlacher, A., Kelly, A., Salamero, J., Powis, S.H., Donato, L., Bausinger, H., et al. (1994). Homozygous human TAP peptide transporter mutation in HLA class I deficiency. Science 265:237-241.
9. Yang, Y., Fruh, K., Chambers, J., Waters, J.B., Wu, L., Spies, T., Peterson, P.A. (1992). Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules. J. Biol. Chem. 267:11669.
10. Neefjes, J., Momburg, F., Haemmerling, G.J. (1993). Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science 261:769-771.
11. Ahn, K., Meyer, T.H., Uebel, S., Sempe, P., Djaballah, H., Yang, Y., Peterson, P.A., Fruh, K., Tampe, R. (1996). Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus protein ICP47. EMBO J. 15:3247-3255.