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Volumn 10, Issue 2, 1999, Pages 139-146

Antitumor drug delivery by tissue electroporation

Author keywords

Adjuvant immunotherapy; Anticancer drug; Drug resistance; Electrochemotherapy; Electrogene therapy; Electropermeabilization

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CISPLATIN; CONGOCIDINE; DACTINOMYCIN; INTERLEUKIN 2;

EID: 0033061978     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199902000-00001     Document Type: Review
Times cited : (12)

References (64)
  • 1
    • 0013629394 scopus 로고
    • Electroporation and electrofusion
    • New York: Plenum Press
    • Neumann E, Sowers AE, Jordan CA, eds. Electroporation and electrofusion. In: Cell Biology. New York: Plenum Press 1989.
    • (1989) Cell Biology
    • Neumann, E.1    Sowers, A.E.2    Jordan, C.A.3
  • 3
    • 0029437811 scopus 로고
    • Electroporation theory: Concepts and mechanisms
    • Weaver JC. Electroporation theory: concepts and mechanisms. Methods Mol Biol 1995; 48: 3-28.
    • (1995) Methods Mol Biol , vol.48 , pp. 3-28
    • Weaver, J.C.1
  • 4
    • 0025009441 scopus 로고
    • Electropermeabilization of mammalian cells. Quantitative analysis of the phenomenon
    • Rols MP, Teissie J Electropermeabilization of mammalian cells. Quantitative analysis of the phenomenon. Biophys J 1990; 58: 1089-98.
    • (1990) Biophys J , vol.58 , pp. 1089-1098
    • Rols, M.P.1    Teissie, J.2
  • 5
    • 0025915115 scopus 로고
    • Electroporation of cell membranes
    • Tsong TY. Electroporation of cell membranes. Biophys J 1991; 60: 297-306.
    • (1991) Biophys J , vol.60 , pp. 297-306
    • Tsong, T.Y.1
  • 6
    • 0027474245 scopus 로고
    • Electroporation: A general phenomenon for manipulating cells and tissues
    • Weaver JC. Electroporation: a general phenomenon for manipulating cells and tissues. J Cell Biochem 1993; 51: 426-35.
    • (1993) J Cell Biochem , vol.51 , pp. 426-435
    • Weaver, J.C.1
  • 7
    • 0027176978 scopus 로고
    • Cell electropermeabilization: A new tool for biochemical and pharmacological studies
    • Orlowski S, Mir LM. Cell electropermeabilization: a new tool for biochemical and pharmacological studies. Biochim Biophys Acta 1993; 1154: 51-63.
    • (1993) Biochim Biophys Acta , vol.1154 , pp. 51-63
    • Orlowski, S.1    Mir, L.M.2
  • 8
    • 0028082251 scopus 로고
    • Electropermeabilization of cells in tissues assessed by the qualitative and quantitative electroloading of bleomycin
    • Belehradek J Jr, Orlowski S, Ramirez LH, Pron G, Poddevin B, Mir LM. Electropermeabilization of cells in tissues assessed by the qualitative and quantitative electroloading of bleomycin. Biochim Biophys Acta 1993; 1190: 155-63.
    • (1993) Biochim Biophys Acta , vol.1190 , pp. 155-163
    • Belehradek J., Jr.1    Orlowski, S.2    Ramirez, L.H.3    Pron, G.4    Poddevin, B.5    Mir, L.M.6
  • 9
    • 0023571678 scopus 로고
    • Effects of a high-voltage electrical impulse and an anticancer drug on in vivo growing tumors
    • Okino M, Mohri H. Effects of a high-voltage electrical impulse and an anticancer drug on in vivo growing tumors. Jpn J Cancer Res 1987; 78: 1319-21.
    • (1987) Jpn J Cancer Res , vol.78 , pp. 1319-1321
    • Okino, M.1    Mohri, H.2
  • 10
    • 0026101653 scopus 로고
    • Electrochemotherapy: Potentiation of antitumor effect of bleomycin by local electric pluses
    • Mir LM, Orlowski S, Belehradek J Jr, Paoletti C. Electrochemotherapy: potentiation of antitumor effect of bleomycin by local electric pluses. Eur J Cancer 1991; 27: 68-72.
    • (1991) Eur J Cancer , vol.27 , pp. 68-72
    • Mir, L.M.1    Orlowski, S.2    Belehradek J., Jr.3    Paoletti, C.4
  • 12
    • 0028908313 scopus 로고
    • Treatment of cutaneous nodules using electrochemotherapy
    • Heller R. Treatment of cutaneous nodules using electrochemotherapy. J Fla Med Ass. 1995; 82: 147-50.
    • (1995) J Fla Med Ass. , vol.82 , pp. 147-150
    • Heller, R.1
  • 13
    • 13344275233 scopus 로고    scopus 로고
    • Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy
    • Heller R, Jaroszeski MJ, Glass LF, et al. Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy. Cancer 1996; 77: 964-71.
    • (1996) Cancer , vol.77 , pp. 964-971
    • Heller, R.1    Jaroszeski, M.J.2    Glass, L.F.3
  • 14
    • 0001850880 scopus 로고
    • Physiological resistance to the treatment of solid tumors
    • Teicher BA, ed. New York: Marcel Dekker
    • Jain RK. Physiological resistance to the treatment of solid tumors. In: Teicher BA, ed. Drug resistance in oncology. New York: Marcel Dekker 1993: 87-105.
    • (1993) Drug Resistance in Oncology , pp. 87-105
    • Jain, R.K.1
  • 15
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain RK. Barriers to drug delivery in solid tumors. Sci Am 1994; 271: 58-65.
    • (1994) Sci Am , vol.271 , pp. 58-65
    • Jain, R.K.1
  • 16
    • 33845220691 scopus 로고
    • Tissue electroporation for localized drug delivery
    • Blank M, ed. Washington, DC: American Chemical Society
    • Weaver JC, Langer R, Potts RO. Tissue electroporation for localized drug delivery. In: Blank M, ed. Advances in chemistry series. Washington, DC: American Chemical Society 1995; 205: 301-16.
    • (1995) Advances in Chemistry Series , vol.205 , pp. 301-316
    • Weaver, J.C.1    Langer, R.2    Potts, R.O.3
  • 17
    • 0024244839 scopus 로고
    • Transient electropermeabilization of cells in culture: Increase of the cytotoxicity of anticancer drugs
    • Orlowski S, Belehradek J Jr, Paoletti C, Mir LM. Transient electropermeabilization of cells in culture: increase of the cytotoxicity of anticancer drugs. Biochem Pharmacol 1988; 37: 4727-33.
    • (1988) Biochem Pharmacol , vol.37 , pp. 4727-4733
    • Orlowski, S.1    Belehradek J., Jr.2    Paoletti, C.3    Mir, L.M.4
  • 18
    • 0023895373 scopus 로고
    • Introduction of definite amounts of nonpermeant molecules into living cells after electropermeabilization: Direct access to the cytosol
    • Mir LM, Banoun H, Paoletti C. Introduction of definite amounts of nonpermeant molecules into living cells after electropermeabilization: direct access to the cytosol. Exp Cell Res 1988; 175: 15-25.
    • (1988) Exp Cell Res , vol.175 , pp. 15-25
    • Mir, L.M.1    Banoun, H.2    Paoletti, C.3
  • 19
    • 0024554376 scopus 로고
    • Voltage-dependent introduction of a d-[α] octothymidylate into electropermeabilized cells
    • Bazile D, Mir LM, Paoletti C. Voltage-dependent introduction of a d-[α] octothymidylate into electropermeabilized cells. Biochem Biophys Res Commun 1989; 159: 633-9.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 633-639
    • Bazile, D.1    Mir, L.M.2    Paoletti, C.3
  • 21
    • 0029099862 scopus 로고
    • Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum (II) in mice
    • Serša G, Èemaar M, Miklavèiè D. Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum (II) in mice. Cancer Res. 1995; 55: 3450-5.
    • (1995) Cancer Res. , vol.55 , pp. 3450-3455
    • Serša, G.1    Èemaar, M.2    Miklavèiè, D.3
  • 22
    • 0030047319 scopus 로고    scopus 로고
    • Antitumor electrochemtherapy: New advances in the clinical protocol
    • Domenge C, Orlowski S, Luboinski B, et al. Antitumor electrochemtherapy: new advances in the clinical protocol. Cancer 1996; 77: 956-63.
    • (1996) Cancer , vol.77 , pp. 956-963
    • Domenge, C.1    Orlowski, S.2    Luboinski, B.3
  • 23
    • 0031148787 scopus 로고    scopus 로고
    • Effects of electrochemotherapy on CaSki cells derived from a cervical squamous cell carcinoma
    • Yabushita H, Yoshikawa K, Hirata M, et al. Effects of electrochemotherapy on CaSki cells derived from a cervical squamous cell carcinoma. Gynecol Oncol 1997; 65: 297-303.
    • (1997) Gynecol Oncol , vol.65 , pp. 297-303
    • Yabushita, H.1    Yoshikawa, K.2    Hirata, M.3
  • 25
    • 18744427501 scopus 로고    scopus 로고
    • Changing electrode orientation improves the efficacy of electrochemotherapy of solid tumors in mice
    • Serša G, Eemaar M, Semrov D, Miklavèiè D. Changing electrode orientation improves the efficacy of electrochemotherapy of solid tumors in mice. Bioelectrochem Bioenerget 1996; 39: 61-6.
    • (1996) Bioelectrochem Bioenerget , vol.39 , pp. 61-66
    • Serša, G.1    Eemaar, M.2    Semrov, D.3    Miklavèiè, D.4
  • 28
    • 0031038607 scopus 로고    scopus 로고
    • Effective treatment of B16 melanoma by direct delivery of bleomycin using electrochemotherapy
    • Heller R, Jaroszeski M, Perrott R, Messina J, Gilbert R. Effective treatment of B16 melanoma by direct delivery of bleomycin using electrochemotherapy. Melanoma Res 1997; 7: 10-8.
    • (1997) Melanoma Res , vol.7 , pp. 10-18
    • Heller, R.1    Jaroszeski, M.2    Perrott, R.3    Messina, J.4    Gilbert, R.5
  • 29
    • 0028047504 scopus 로고
    • Electrochemotherapy a novel method of cancer treatment
    • Dev SB, Hofmann GA. Electrochemotherapy a novel method of cancer treatment. Cancer Treat Rev 1994; 20: 105-15.
    • (1994) Cancer Treat Rev , vol.20 , pp. 105-115
    • Dev, S.B.1    Hofmann, G.A.2
  • 30
    • 0022906301 scopus 로고
    • Increase in cis-dichlorodiammineplatinum (II) cytotoxicity upon reversible electropermeabilization of the plasma membrane in cultured human NHIK 3025 cells
    • Melvik JE, Pettersen EO, Gordon PB, Selgen PO. Increase in cis-dichlorodiammineplatinum (II) cytotoxicity upon reversible electropermeabilization of the plasma membrane in cultured human NHIK 3025 cells. Eur J Cancer Clin Oncol 1986; 22: 1523-30.
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 1523-1530
    • Melvik, J.E.1    Pettersen, E.O.2    Gordon, P.B.3    Selgen, P.O.4
  • 31
    • 0000070176 scopus 로고
    • Response of cisplatin resistant tumor cells to electroporation and cisplatin
    • Nutt AK, Mansouri A, Henle KJ. Response of cisplatin resistant tumor cells to electroporation and cisplatin. Proc Am Ass Cancer Res 1991; 32: 375.
    • (1991) Proc Am Ass Cancer Res , vol.32 , pp. 375
    • Nutt, A.K.1    Mansouri, A.2    Henle, K.J.3
  • 32
    • 0025840591 scopus 로고
    • Very high cytotoxicity of bleomycin introduced into the cytosol of cells in culture
    • Poddevin B, Orlowski S, Belehradek J Jr, Mir LM. Very high cytotoxicity of bleomycin introduced into the cytosol of cells in culture. Biochem Pharmacol 1991; 42: S67-75.
    • (1991) Biochem Pharmacol , vol.42
    • Poddevin, B.1    Orlowski, S.2    Belehradek J., Jr.3    Mir, L.M.4
  • 33
    • 0028338391 scopus 로고
    • Potentiation of antitumor effect of bleomycin followed by local electric pulses in mouse bladder tumor
    • Yamaguchi O, Irisawa C, Baba K, Ogihara M, Yokota T, Shiraiwa Y. Potentiation of antitumor effect of bleomycin followed by local electric pulses in mouse bladder tumor. Tohoku J Exp Med 1995; 172: 291-3.
    • (1995) Tohoku J Exp Med , vol.172 , pp. 291-293
    • Yamaguchi, O.1    Irisawa, C.2    Baba, K.3    Ogihara, M.4    Yokota, T.5    Shiraiwa, Y.6
  • 34
    • 0030939725 scopus 로고    scopus 로고
    • Electrochemotherapy significantly inhibits the growth of colon 26 tumors in mice
    • Tada T, Matsumoto K, Suzuki H. Electrochemotherapy significantly inhibits the growth of colon 26 tumors in mice. Surg. Today 1997; 27: 506-10.
    • (1997) Surg. Today , vol.27 , pp. 506-510
    • Tada, T.1    Matsumoto, K.2    Suzuki, H.3
  • 35
    • 85038183340 scopus 로고    scopus 로고
    • Treating pancreatic cancers: Is the combination of chemotherapy with pulsed electric field the answer?
    • Dev SB, Nanda GS. Treating pancreatic cancers: is the combination of chemotherapy with pulsed electric field the answer? Proc Am Ass Cancer Res 1996; 37: A2054.
    • (1996) Proc Am Ass Cancer Res , vol.37
    • Dev, S.B.1    Nanda, G.S.2
  • 37
    • 0028894039 scopus 로고
    • Treatment of B16 mouse melanoma with the combination of electropermeabilization and chemotherapy
    • Heller R, Jaroszeski M, Leo-Messina J, et al. Treatment of B16 mouse melanoma with the combination of electropermeabilization and chemotherapy. Bioelectrochem Bioenerget 1995; 36: 83-7.
    • (1995) Bioelectrochem Bioenerget , vol.36 , pp. 83-87
    • Heller, R.1    Jaroszeski, M.2    Leo-Messina, J.3
  • 38
    • 0025109658 scopus 로고
    • The effects of a single high voltage electrical stimulation with an anticancer drug on in vivo growing malignant tumors
    • Okino M, Esato K. The effects of a single high voltage electrical stimulation with an anticancer drug on in vivo growing malignant tumors. Jpn J Surg 1990; 20: 197-204.
    • (1990) Jpn J Surg , vol.20 , pp. 197-204
    • Okino, M.1    Esato, K.2
  • 39
    • 0025253872 scopus 로고
    • Anticancer effect of high voltage pulses combined with concentration dependent anticancer drugs on Lewis lung carcinoma in vivo
    • Kanesada H. Anticancer effect of high voltage pulses combined with concentration dependent anticancer drugs on Lewis lung carcinoma in vivo (in Japanese, abstract and tables in English). J Jpn Soc Cancer Ther 1990; 25: 2640-8.
    • (1990) J Jpn Soc Cancer Ther , vol.25 , pp. 2640-2648
    • Kanesada, H.1
  • 41
    • 0031055925 scopus 로고    scopus 로고
    • In vivo antitumor effects of electrochemotherapy in a hepatoma model
    • Zaroszeski MJ, Gilbert RA, Heller R. In vivo antitumor effects of electrochemotherapy in a hepatoma model. Biochim Biophys Acta 1997; 1334: 15-8.
    • (1997) Biochim Biophys Acta , vol.1334 , pp. 15-18
    • Zaroszeski, M.J.1    Gilbert, R.A.2    Heller, R.3
  • 42
    • 0030020942 scopus 로고    scopus 로고
    • Bleomycin-mediated electrochemotherapy of basal-cell carcinoma
    • Glass LF, Fenske NA, Jaroszeski M, et al. Bleomycin-mediated electrochemotherapy of basal-cell carcinoma. J Am Acad Dermatol 1996; 34: 82-6.
    • (1996) J Am Acad Dermatol , vol.34 , pp. 82-86
    • Glass, L.F.1    Fenske, N.A.2    Jaroszeski, M.3
  • 43
    • 0026264930 scopus 로고
    • Electrochemotherapy, a new antitumor treatment: First clinical trial
    • Mir LM, Relehradek M, Domenge C, et al. Electrochemotherapy, a new antitumor treatment: first clinical trial (in French, abstract in English). C R Acad Sci III 1991; 313: 613-8.
    • (1991) C R Acad Sci III , vol.313 , pp. 613-618
    • Mir, L.M.1    Relehradek, M.2    Domenge, C.3
  • 45
    • 0026856236 scopus 로고
    • Electrochemotherapy tumor treatment is improved by interleukin-2 stimulation of hosts defenses
    • Mir LM, Orlowski S, Poddevin B, Belehradek J Jr. Electrochemotherapy tumor treatment is improved by interleukin-2 stimulation of hosts defenses. Eur Cytokine Netw 1992; 3: 331-4.
    • (1992) Eur Cytokine Netw , vol.3 , pp. 331-334
    • Mir, L.M.1    Orlowski, S.2    Poddevin, B.3    Belehradek J., Jr.4
  • 46
    • 0029859843 scopus 로고    scopus 로고
    • Electrochemotherapy with bleomycin in SA-1 tumor hearing mice: Natural resistance and immune responsiveness
    • Serša G, Kotnik V, Èemaar M, Miklavèiè D, Kotnik A. Electrochemotherapy with bleomycin in SA-1 tumor hearing mice: natural resistance and immune responsiveness. Anti-Cancer Drugs 1996; 7: 785-91.
    • (1996) Anti-Cancer Drugs , vol.7 , pp. 785-791
    • Serša, G.1    Kotnik, V.2    Èemaar, M.3    Miklavèiè, D.4    Kotnik, A.5
  • 47
    • 0030472123 scopus 로고    scopus 로고
    • Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin 2
    • Quintin-Colonna F, Devauchelle P, Fradelizi D, et al. Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin 2. Gene Therapy 1996; 3: 1104-12.
    • (1996) Gene Therapy , vol.3 , pp. 1104-1112
    • Quintin-Colonna, F.1    Devauchelle, P.2    Fradelizi, D.3
  • 48
    • 0026752399 scopus 로고
    • Potentiation of the antitumor effect of electrochemotherapy by an immunotherapy with allogeneic cells producing interleukin 2
    • Mir LM, Roth C, Orlowski S, et al. Potentiation of the antitumor effect of electrochemotherapy by an immunotherapy with allogeneic cells producing interleukin 2. C R Acad Sci III 1992; 314: 539-44.
    • (1992) C R Acad Sci III , vol.314 , pp. 539-644
    • Mir, L.M.1    Roth, C.2    Orlowski, S.3
  • 49
    • 0028871192 scopus 로고
    • Systemic antitumor effects of electrochemotherapy combined with histoincompatible cells secreting interleukin-2
    • Mir LM, Roth C, Orlowski S, et al. Systemic antitumor effects of electrochemotherapy combined with histoincompatible cells secreting interleukin-2. J Immunother Emphasis Tumor Immunol 1995; 17: 30-8.
    • (1995) J Immunother Emphasis Tumor Immunol , vol.17 , pp. 30-38
    • Mir, L.M.1    Roth, C.2    Orlowski, S.3
  • 50
    • 0342940770 scopus 로고    scopus 로고
    • Anti-tumor effectiveness of electrochemotherapy with bleomycin is increased by TNF-alpha on SA-1 tumors in mice
    • Serša G, Èemaar M, Menart V, Gaberc-Porekar V, Miklavèiè D. Anti-tumor effectiveness of electrochemotherapy with bleomycin is increased by TNF-alpha on SA-1 tumors in mice. Cancer Lett 1997; 116: 85-92.
    • (1997) Cancer Lett , vol.116 , pp. 85-92
    • Serša, G.1    Èemaar, M.2    Menart, V.3    Gaberc-Porekar, V.4    Miklavèiè, D.5
  • 52
    • 0004027585 scopus 로고
    • Electrically-induced DNA transfer into cells. Electrotransfection in vivo
    • Wolff JA, ed. Boston: Birkhaüser
    • Sukharev SI, Titomirov AV, Klenchin VA. Electrically-induced DNA transfer into cells. Electrotransfection in vivo. In: Wolff JA, ed. Gene therapeutics. Boston: Birkhaüser 1994: 210-32.
    • (1994) Gene Therapeutics , pp. 210-232
    • Sukharev, S.I.1    Titomirov, A.V.2    Klenchin, V.A.3
  • 53
    • 0025109574 scopus 로고
    • Gene transfer into brain tumor cell lines: Reporter gene expression using various cellular and viral promotors
    • Oellig C, Seliger B. Gene transfer into brain tumor cell lines: reporter gene expression using various cellular and viral promotors. J Neurosci Res 1990; 26: 390-6.
    • (1990) J Neurosci Res , vol.26 , pp. 390-396
    • Oellig, C.1    Seliger, B.2
  • 54
    • 0023375341 scopus 로고
    • Electroporation: Parameters affecting transfer of DNA into mammalian cells
    • Knutson JC, Yee D. Electroporation: parameters affecting transfer of DNA into mammalian cells. Anal Biochem 1987; 164: 44-52.
    • (1987) Anal Biochem , vol.164 , pp. 44-52
    • Knutson, J.C.1    Yee, D.2
  • 55
    • 9044230116 scopus 로고    scopus 로고
    • High efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in-vivo electroporation
    • Nishi T, Yoshizato K, Yamashiro S, et al. High efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in-vivo electroporation. Cancer Res 1996; 56: 1050-5.
    • (1996) Cancer Res , vol.56 , pp. 1050-1055
    • Nishi, T.1    Yoshizato, K.2    Yamashiro, S.3
  • 56
    • 0030575192 scopus 로고    scopus 로고
    • In vivo gene electroinjection and expression in rat liver
    • Heller R, Jaroszeski M, Atkin A, et al. In vivo gene electroinjection and expression in rat liver. FEBS Lett 1996; 389: 225-8.
    • (1996) FEBS Lett , vol.389 , pp. 225-228
    • Heller, R.1    Jaroszeski, M.2    Atkin, A.3
  • 57
    • 0029126687 scopus 로고
    • Biomedical applications of electric pulses with special emphasis on antitumor electrochemotherapy
    • Mir LM, Orlowski S, Belehradek J Jr, et al. Biomedical applications of electric pulses with special emphasis on antitumor electrochemotherapy. Bioelectrochem Bioenerget 1995; 38: 203-7.
    • (1995) Bioelectrochem Bioenerget , vol.38 , pp. 203-207
    • Mir, L.M.1    Orlowski, S.2    Belehradek J., Jr.3
  • 58
    • 0029785865 scopus 로고    scopus 로고
    • Bleomycin antibiotics and their role in cancer chemotherapy
    • Huang LR, Xie Y, Lown JW. Bleomycin antibiotics and their role in cancer chemotherapy. Expert Opin Ther Patents 1996; 6: 893-9.
    • (1996) Expert Opin Ther Patents , vol.6 , pp. 893-899
    • Huang, L.R.1    Xie, Y.2    Lown, J.W.3
  • 61
    • 85038181811 scopus 로고
    • Electrochemotherapy: Preclinical data on normal tissue tolerance and antitumor effects in rabbits
    • Ramirez LH, Bognel C, Zhao ZX, et al. Electrochemotherapy: preclinical data on normal tissue tolerance and antitumor effects in rabbits. Proc Am Ass Cancer Res 1994; 35: A1969.
    • (1994) Proc Am Ass Cancer Res , vol.35
    • Ramirez, L.H.1    Bognel, C.2    Zhao, Z.X.3
  • 63
    • 85038176306 scopus 로고
    • Electrochemotherapy: A new antitumor treatment using electric pulses
    • Blank M ed. San Francisco, CA: San Francisco Press
    • Mir LM, Orlowski S, Belehradek J Jr, et al. Electrochemotherapy: a new antitumor treatment using electric pulses. In: Blank M ed. Electricity and magnetism in biology and medicine. San Francisco, CA: San Francisco Press 1993: 119-21.
    • (1993) Electricity and Magnetism in Biology and Medicine , pp. 119-121
    • Mir, L.M.1    Orlowski, S.2    Belehradek J., Jr.3
  • 64
    • 0031088811 scopus 로고    scopus 로고
    • Treatment of cancer using pulsed electric field in combination with chemotherapeutic agents or genes
    • Nishi T, Dev SB, Yoshizato K, Kuratsu J, Ushio Y. Treatment of cancer using pulsed electric field in combination with chemotherapeutic agents or genes. Hum Cell 1997; 10: 81-6.
    • (1997) Hum Cell , vol.10 , pp. 81-86
    • Nishi, T.1    Dev, S.B.2    Yoshizato, K.3    Kuratsu, J.4    Ushio, Y.5


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