Effect of temperature on drug release and drug absorption in mixed type diclofenac sodium suppositories

Yakugaku Zasshi

Volumn 119, Issue 2, 1999, Pages 170-177

  Iwata, Masanori ^a,b   Takayama, Kozo ^b   Takahashi, Yuri ^a,b   Obata, Yasuko ^b   Machida, Yoshiharu ^b   Nagai, Tsuneji ^b   Shirotake, Shoichi ^a  

^a YOKOHAMA CITY UNIVERSITY HOSPITAL   (Japan)

^b HOSHI UNIVERSITY   (Japan)

Author keywords

DDS; Diclofenac sodium; Image analysis; Rectal temperature; Suppository; Witepsol

Indexed keywords

DICLOFENAC; WITEPSOL; WITEPSOL E 85; WITEPSOL W 35;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG RELEASE; NONHUMAN; RABBIT; SUPPOSITORY; TEMPERATURE DEPENDENCE;

EID: 0033061707     PISSN: 00316903     EISSN: None     Source Type: Journal    
DOI: 10.1248/yakushi1947.119.2_170     Document Type: Article

References (13)

1. Akimoto J., Takayama K., Isawa K., Nagai T., Int. J. Pharm., 128, 251-260 (1996).
2. Obata Y., Takayama K., Okabe H., Nagai T., Drug Design Delivery, 6, 319-328 (1990).