메뉴 건너뛰기




Volumn 63, Issue 3, 1999, Pages 501-506

Oral versus transdermal selegiline: Antidepressant-like activity in rats

Author keywords

Antidepressant like activity; Forced swim test; l deprenyl; Monoamine oxidases; Selegiline; Transdermal drug administration

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; SELEGILINE;

EID: 0033061532     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(99)00016-7     Document Type: Article
Times cited : (35)

References (30)
  • 1
    • 0022253848 scopus 로고
    • Guinea pig striatum as a model of human dopamine deamination: The role of monoamine oxidase isozyme ratio, localization, and affinity for substrate in synaptic dopamine metabolism
    • Azzaro A.J., King J., Kotzuk J., Schoepp D.D., Frost J., Schochet S. Guinea pig striatum as a model of human dopamine deamination. The role of monoamine oxidase isozyme ratio, localization, and affinity for substrate in synaptic dopamine metabolism J. Neurochem. 45:1985;949-956.
    • (1985) J. Neurochem. , vol.45 , pp. 949-956
    • Azzaro, A.J.1    King, J.2    Kotzuk, J.3    Schoepp, D.D.4    Frost, J.5    Schochet, S.6
  • 2
    • 0029832107 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of a selegiline transdermal system relative to single-dose oral administration in the elderly
    • Barrett J.S., Hochadel T.J., Morales R.J., Rohatagi S., DeWitt K.E., Watson S.K., DiSanto A.R. Pharmacokinetics and safety of a selegiline transdermal system relative to single-dose oral administration in the elderly. Am. J. Ther. 3:1996;688-698.
    • (1996) Am. J. Ther. , vol.3 , pp. 688-698
    • Barrett, J.S.1    Hochadel, T.J.2    Morales, R.J.3    Rohatagi, S.4    Dewitt, K.E.5    Watson, S.K.6    Disanto, A.R.7
  • 3
    • 0028030607 scopus 로고
    • Possible mechanisms of action of (-)deprenyl and other MAO-B inhibitors in some neurologic and psychiatric disorders
    • Berry M.D., Juorio A.V., Paterson I.A. Possible mechanisms of action of (-)deprenyl and other MAO-B inhibitors in some neurologic and psychiatric disorders. Prog. Neurobiol. 44:1994;141-161.
    • (1994) Prog. Neurobiol. , vol.44 , pp. 141-161
    • Berry, M.D.1    Juorio, A.V.2    Paterson, I.A.3
  • 4
    • 0016709622 scopus 로고
    • The monoamine oxidase B inhibitor deprenyl potentiates phenylethylamine behaviour in rats without inhibition of catecholamine metabolite formation
    • Braestrup C., Andersen H., Randrup A. The monoamine oxidase B inhibitor deprenyl potentiates phenylethylamine behaviour in rats without inhibition of catecholamine metabolite formation. Eur. J. Pharmacol. 34:1975;181-187.
    • (1975) Eur. J. Pharmacol. , vol.34 , pp. 181-187
    • Braestrup, C.1    Andersen, H.2    Randrup, A.3
  • 5
    • 0029049352 scopus 로고
    • A comparison of the behavioral effects of minaprine, amphetamine and stress
    • Cabib S., Zocchi A., Puglisi-Allegra S. A comparison of the behavioral effects of minaprine, amphetamine and stress. Psychopharmacology (Berlin). 121:1995;73-80.
    • (1995) Psychopharmacology (Berlin) , vol.121 , pp. 73-80
    • Cabib, S.1    Zocchi, A.2    Puglisi-Allegra, S.3
  • 6
    • 0019964615 scopus 로고
    • A pharmacological analysis of the hyperactivity syndrome induced by beta-phenylethylamine in the mouse
    • Dourish C.T. A pharmacological analysis of the hyperactivity syndrome induced by beta-phenylethylamine in the mouse. Br. J. Pharmacol. 77:1982;129-139.
    • (1982) Br. J. Pharmacol. , vol.77 , pp. 129-139
    • Dourish, C.T.1
  • 7
    • 0026315038 scopus 로고
    • Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; Effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons
    • Engberg G., Elebring T., Nissbrandt H. Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; Effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons. J. Pharmacol. Exp. Ther. 259:1991;841-847.
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , pp. 841-847
    • Engberg, G.1    Elebring, T.2    Nissbrandt, H.3
  • 8
    • 0022377075 scopus 로고
    • The functional consequences of inhibition of monoamine oxidase type B: Comparison of the pharmacological properties of L-deprenyl and MDL 72145
    • Fozard J.R., Zreika M., Robin M., Palfreyman M.G. The functional consequences of inhibition of monoamine oxidase type B. Comparison of the pharmacological properties of L-deprenyl and MDL 72145 Naunyn Schmiedebergs Arch. Pharmacol. 331:1985;186-193.
    • (1985) Naunyn Schmiedebergs Arch. Pharmacol. , vol.331 , pp. 186-193
    • Fozard, J.R.1    Zreika, M.2    Robin, M.3    Palfreyman, M.G.4
  • 10
    • 0026480922 scopus 로고
    • Changes in spontaneous behavior in the dog following oral administration of L-deprenyl
    • Head E., Milgram N.W. Changes in spontaneous behavior in the dog following oral administration of L-deprenyl. Pharmacol. Biochem. Behav. 43:1992;749-757.
    • (1992) Pharmacol. Biochem. Behav. , vol.43 , pp. 749-757
    • Head, E.1    Milgram, N.W.2
  • 13
    • 0020085133 scopus 로고
    • Metabolism of (-) deprenyl to amphetamine and methamphetamine may be responsible for deprenyl's therapeutic benefit: A biochemical assessment
    • Karoum F., Chuang L.W., Eisler T., Calne D.B., Liebowitz M.R., Quitkin F.M., Klein D.F., Wyatt R.J. Metabolism of (-) deprenyl to amphetamine and methamphetamine may be responsible for deprenyl's therapeutic benefit. A biochemical assessment Neurology. 32:1982;503-509.
    • (1982) Neurology , vol.32 , pp. 503-509
    • Karoum, F.1    Chuang, L.W.2    Eisler, T.3    Calne, D.B.4    Liebowitz, M.R.5    Quitkin, F.M.6    Klein, D.F.7    Wyatt, R.J.8
  • 14
    • 0030300165 scopus 로고    scopus 로고
    • The clinical potential of Deprenyl in neurologic and psychiatric disorders
    • Kuhn W., Muller T. The clinical potential of Deprenyl in neurologic and psychiatric disorders. J. Neural Transm. 48:1996;85-93.
    • (1996) J. Neural Transm. , vol.48 , pp. 85-93
    • Kuhn, W.1    Muller, T.2
  • 15
    • 0242610770 scopus 로고
    • Do MAO-B inhibitors have any role in the treatment of depression
    • I. Szelenyi. Basel, Switzerland: Birkhauser Verlag
    • Laux G. Do MAO-B inhibitors have any role in the treatment of depression. Szelenyi I. Inhibitors of monoamine oxidase B. 1993;319-326 Birkhauser Verlag, Basel, Switzerland.
    • (1993) Inhibitors of Monoamine Oxidase B , pp. 319-326
    • Laux, G.1
  • 17
    • 0020385339 scopus 로고
    • The relative efficacy of l-deprenyl, a selective monoamine oxidase type B inhibitor, in endogenous and nonendogenous depression
    • Mann J.J., Frances A., Kaplan R.D., Kocsis J., Peselow E.D., Gershon S. The relative efficacy of l-deprenyl, a selective monoamine oxidase type B inhibitor, in endogenous and nonendogenous depression. J. Clin. Psychopharmacol. 2:1982;54-57.
    • (1982) J. Clin. Psychopharmacol. , vol.2 , pp. 54-57
    • Mann, J.J.1    Frances, A.2    Kaplan, R.D.3    Kocsis, J.4    Peselow, E.D.5    Gershon, S.6
  • 18
    • 0020462599 scopus 로고
    • Differential efficacy of L-deprenyl, a selective MAO type-B inhibitor, in endogenous and nonendogenous depression
    • Mann J.J., Frances A., Peselow E.D., Gershon S. Differential efficacy of L-deprenyl, a selective MAO type-B inhibitor, in endogenous and nonendogenous depression. Psychopharmacol. Bull. 18:1982;182-184.
    • (1982) Psychopharmacol. Bull. , vol.18 , pp. 182-184
    • Mann, J.J.1    Frances, A.2    Peselow, E.D.3    Gershon, S.4
  • 19
    • 0019185890 scopus 로고
    • L-Deprenyl, a selective monoamine oxidase type-B inhibitor in endogenous depression
    • Mann J.J., Gershon S. L-Deprenyl, a selective monoamine oxidase type-B inhibitor in endogenous depression. Life Sci. 26:1980;877-882.
    • (1980) Life Sci. , vol.26 , pp. 877-882
    • Mann, J.J.1    Gershon, S.2
  • 20
    • 0020570351 scopus 로고
    • L-Deprenil, a selective monoamine oxidase type B inhibitor, in the treatment of depression: A double blind evaluation
    • Mendlewicz J., Youdim M.B.H. L-Deprenil, a selective monoamine oxidase type B inhibitor, in the treatment of depression. A double blind evaluation Br. J. Psychiatry. 142:1983;508-511.
    • (1983) Br. J. Psychiatry , vol.142 , pp. 508-511
    • Mendlewicz, J.1    Youdim, M.B.H.2
  • 21
    • 0026476651 scopus 로고
    • Deprenyl alters behavior and caudate dopamine through an amphetamine-like action
    • Okuda C., Segal D.S., Kuczenski R. Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. Pharmacol. Biochem. Behav. 43:1992;1075-1080.
    • (1992) Pharmacol. Biochem. Behav. , vol.43 , pp. 1075-1080
    • Okuda, C.1    Segal, D.S.2    Kuczenski, R.3
  • 22
    • 0025647353 scopus 로고
    • 2-Phenylethylamine: A modulator of catecholamine transmission in the mammalian central nervous system?
    • Paterson I.A., Juorio A.V., Boulton A.A. 2-Phenylethylamine. A modulator of catecholamine transmission in the mammalian central nervous system? J. Neurochem. 55:1990;1827-1837.
    • (1990) J. Neurochem. , vol.55 , pp. 1827-1837
    • Paterson, I.A.1    Juorio, A.V.2    Boulton, A.A.3
  • 23
    • 0018268297 scopus 로고
    • Behavioural despair in rats: A new model sensitive to antidepressant treatments
    • Porsolt R.D., Anton G., Blavet N., Jalfre M. Behavioural despair in rats. A new model sensitive to antidepressant treatments Eur. J. Pharmacol. 47:1978;379-391.
    • (1978) Eur. J. Pharmacol. , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 24
    • 0018068203 scopus 로고
    • Amphetamine and 2-phenylethylamine in post-mortem Parkinsonian brain after (-)deprenyl administration
    • Reynolds G.P., Riederer P., Sandler M., Jellinger K., Seemann D. Amphetamine and 2-phenylethylamine in post-mortem Parkinsonian brain after (-)deprenyl administration. J. Neural Transm. 43:1978;271-277.
    • (1978) J. Neural Transm. , vol.43 , pp. 271-277
    • Reynolds, G.P.1    Riederer, P.2    Sandler, M.3    Jellinger, K.4    Seemann, D.5
  • 25
    • 0030881523 scopus 로고    scopus 로고
    • Integrated pharmacokinetic and metabolic modeling of selegiline and metabolites after transdermal administration
    • Rohatagi R., Barrett J.S., DeWitt K.E., Morales R.J. Integrated pharmacokinetic and metabolic modeling of selegiline and metabolites after transdermal administration. Biopharmacol. Drug Disp. 18:1997;567-584.
    • (1997) Biopharmacol. Drug Disp. , vol.18 , pp. 567-584
    • Rohatagi, R.1    Barrett, J.S.2    Dewitt, K.E.3    Morales, R.J.4
  • 26
    • 0027366111 scopus 로고
    • Induction of antidepressive activity by monoaminergic transplants in rat neocortex
    • Sortwell C.E., Sagen J. Induction of antidepressive activity by monoaminergic transplants in rat neocortex. Pharmacol. Biochem. Behav. 46:1993;225-230.
    • (1993) Pharmacol. Biochem. Behav. , vol.46 , pp. 225-230
    • Sortwell, C.E.1    Sagen, J.2
  • 28
    • 0016074636 scopus 로고
    • The monoamine oxidases of brain: Selective inhibition with drugs and the consequences for the metabolism of the biogenic amines
    • Yang H.Y., Neff N.H. The monoamine oxidases of brain. Selective inhibition with drugs and the consequences for the metabolism of the biogenic amines J. Pharmacol. Exp. Ther. 189:1974;733-740.
    • (1974) J. Pharmacol. Exp. Ther. , vol.189 , pp. 733-740
    • Yang, H.Y.1    Neff, N.H.2
  • 29
    • 0028593637 scopus 로고
    • Amphetamine-like effect of l-deprenyl (selegiline) in drug discrimination studies
    • Yasar S., Bergman J. Amphetamine-like effect of l-deprenyl (selegiline) in drug discrimination studies. Clin. Pharmacol. Ther. 56:1994;768-773.
    • (1994) Clin. Pharmacol. Ther. , vol.56 , pp. 768-773
    • Yasar, S.1    Bergman, J.2
  • 30
    • 0028588040 scopus 로고
    • Pharmacological and clinical implications of MAO-B inhibitors
    • Yu P.H. Pharmacological and clinical implications of MAO-B inhibitors. Gen. Pharmacol. 25:1994;1527-1539.
    • (1994) Gen. Pharmacol. , vol.25 , pp. 1527-1539
    • Yu, P.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.