Long-term follow-up of a randomized trial of interferon therapy for chronic hepatitis B in a predominantly homosexual male population

Journal of Hepatology

Volumn 30, Issue 4, 1999, Pages 557-563

  Chen, Danny K ^a   Yim, Colina ^a   O'Rourke, Keith ^a   Krajden, Mel ^a   Wong, David K H ^a   Heathcote, E Jenny ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

CD4 T lymphocyte count; Hepatitis B; HIV viral load; Homosexual males; Human immunodeficiency virus; Interferon alfa; Long term follow up

Indexed keywords

RECOMBINANT ALPHA INTERFERON; VIRUS DNA;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEALTH STATUS; HEPATITIS; HOMOSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LIVER DISEASE; LONG TERM CARE; LYMPHOCYTE COUNT; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROCONVERSION; TREATMENT OUTCOME; VIRUS REPLICATION;

EID: 0033061188     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80184-6     Document Type: Article

References (30)

1. Liaw Y.F., Tai D.I., Chu C.M., Chen T.J. The development of cirrhosis in subjects with chronic type B hepatitis: a prospective study. Hepatology. 8:1988;493-496.
2. Beasley R.P. Hepatitis B virus The major etiology of hepatocellular carcinoma. Cancer. 61:1988;1942-1956.
3. Krogsgaard K., Lindhardt B.O., Neilsen J.O., Andersson P., Kryger P., Aldershvile J., et al. The influence of HTLV-III infection on the natural history of hepatitis B virus infection in male homosexual HBsAg carriers. Hepatology. 7:1987;37-41.
4. Bodsworth N., Donovan B., Nightengale B.N. The effect of concurrent human immunodeficiency virus infection on chronic hepatitis B: a study of 150 homosexual men. J Infect Dis. 160:1989;577-582.
5. Mai A.L., Yim C., O'Rourke K., Heathcote E.J. The interaction of human immunodeficiency virus infection and hepatitis B virus infection in infected homosexual men. J Clin Gastroenterol. 22:1996;299-304.
6. Wong D.K., Cheung A.M., O'Rourke K., Naylor C.D., Detsky A.S., Heathcote J. Effect of alpha-interferon treatment in subjects with hepatitis B e antigen-positive chronic hepatitis B. Ann Intern Med. 119:1993;312-323.
7. Perrillo R.P., Schiff E.R., Davis G.L., Bodenheimer H.C., Lindsay K., Payne J., et al. A randomized, controlled trial of interferon alfa-2b and after prednisone withdrawal for the treatment of chronic hepatitis B. N Engl J Med. 323:1990;295-301.
8. Brook M.G., Petrovic L., McDonald J.A., Scheuer P.J., Thomas H.C. Histological improvement after anti-viral treatment for chronic hepatitis B virus infection. J Hepatol. 8:1989;218-225.
9. Wong D.K.H., Yim C., Naylor C.D., Chen E., Sherman M., Vas S., et al. Interferon alfa treatment of chronic hepatitis B: randomzed trial in a predominantly homosexual male population. Gastroenterology. 108:1995;165-171.
10. Davis G.L. Interferon treatment of viral hepatitis in immunocompromised subjects. Semin Liver Dis. 9:1989;267-272.
11. Hoofnagle J.H. α-interferon therapy of chronic hepatitis B. Current status and recommendations. J Hepatol. 11:(Suppl):1990;S100-S107.
12. Korenman J., Baker B., Waggoner J., Everheart Je Di Bisceglie A.M., Hoofnagle J.H. Long-term remission of chronic hepatitis B after alpha-interferon therapy. Ann Intern Med. 114:1991;629-634.
13. Carreno V., Castillo I., Molina J., Porres J.C., Bartolome J. Long-term follow-up of hepatitis B chronic carriers who responded to interferon therapy. J Hepatol. 15:1992;102-106.
14. Lok A.S., Chung H.T., Liu V.W., Ma O.C.K. Long-term follow-up of chronic hepatitis B subjects treated with interferon alfa. Gastroenterology. 105:1993;1833-1838.
15. Hope R.L., Weltman M., Dingley J., Fiatarone J., Hope A.H., Craig P.I., et al. Interferon alfa for chronic active hepatitis B. Long-term follow-up of 62 subjects: outcomes and predictors of response. Med J Aust. 162:1995;8-11.
16. Villeneuve J.P., Willems B. Treatment of chronic hepatitis B with interferon: long-term follow-up. Can J Gastroenterol. 10:1996;21-25.
17. Niederau C., Heintges T., Lange S., Goldmann G., Niederau C.M., Mohr L., et al. Long-term follow-up of HBeAg-positive subjects treated with interferon alfa for chronic hepatitis B. N Engl J Med. 334:1996;1422-1427.
18. Lau D.T.Y., Everhart J., Kleiner D.E., Park Y., Vergalla J., Schmid P., et al. Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa. Gastroenterology. 113:1997;1660-1667.
19. Fattovich G., Giustina G., Realdi G., Corrocher, Schalm S.W., et al. Long-term outcome of hepatitis B e antigen-positive patients with compensated cirrhosis treated with interferon alfa. Hepatology. 26:1997;1338-1342.
20. di Martino V., Lunel F., Cadranel J.F., Hoang C., Parlier Y., Le Charpentier Y., et al. Long-term effects of interferon-α in five HIV-positive subjects with chronic hepatitis B. J Viral Hepatol. 3:1996;253-260.
21. Carpenter C.C.J., Fischl M., Hammer S.M., Hirsh M.S., Jacobsen D.M., Katzenstein D.A., et al. Antiretroviral therapy for HIV infection in 1996. JAMA. 276:1996;146-154.
22. Mellors J.W., Rinaldo C.R. Jr., Gupta P., White R.M., Todd J.A., Kingsley L.A. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science. 272:1996;1167-1170.
23. Janssen H.L.A., Schalon S.W., Berk L., de Man R.A., Heijtink R.A. Repeated courses of α-interferon for treatment of chronic hepatitis type B. J Hepatol. 17:(Suppl. 3):1993;S47-S51.
24. Berglund O., Engman K., Ehrnst A., Andersson J., Lidman K., Akerlund B., et al. Combined treatment of symptomatic human immunodeficiency virus type 1 infection with native interferon-α and zidovudine. J Infect Dis. 163:1991;710-715.
25. Lane H.C., Davey V., Kovacs J.A., Feinberg J., Metcalf J.A., Herpin B., et al. Interferon-alpha in subjects with asymptomatic human immunodeficiency virus (HIV) infection. A randomized, placebocontrolled trial. Ann Intern Med. 111:1989;41-50.
26. Scharschmidt B.F., Held M.J., Hollander H.H., Read A.E., Lavine J.E., Veereman G., et al. Hepatitis B in subjects with HIV infection: relationship to AIDS and subject survival. Ann Intern Med. 117:1992;837-838.
27. Solomon R.E., VanRaden M., Kaslow R.A., Lyter D., Visscher B., Farzadegan H., et al. Association of hepatitis B surface antigen and core antibody with acquisition and manifestations of human immunodeficiency virus type 1 infection. Am J Public Health. 80:1990;1475-1478.
28. Schecter M.T., Craib K.J.P., Le T.N., Willoughby B., Douglas B., Sestak P., et al. Progression to AIDS and predictors of AIDS in seroprevalent and serocoincident cohorts of homosexual men. AIDS. 3:1989;347-353.
29. Takeda K., Akahane Y., Suzuki H., Okamoto H., Tsuda F., Miyakawa Y., et al. Defects in the precore region of the HBV genome in subjects with chronic hepatitis B after sustained seroconversion from HBeAg to anti-HBe induced spontaneously or with interferon therapy. Hepatology. 12:1990;1284-1289.
30. Fattovich G., McIntyre G., Thursz M., Colman K., Giuliano G., Alberti A., et al. Hepatitis B virus precore/core variation and interferon therapy. Hepatology. 22:1995;1355-1362.