Phospholipid turnover in the inflamed intestinal mucosa: Arachidonic acid-rich phosphatidyl/plasmenyl-ethanolamine in the mucosa in inflammatory bowel disease

Journal of Gastroenterology

Volumn 34, Issue 1, 1999, Pages 46-53

  Morita, Hiroyoshi ^a   Nakanishi, Kazuko ^b   Dohi, Taeko ^b   Yasugi, Etsuko ^b   Oshima, Mieko ^b  

^a TOKYO TEISHIN HOSPITAL   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Arachidonic acid; Inflammatory bowel disease (IBD); Mucosal phospholipid; Phospholipase A2; Plasmenylethanolamine

Indexed keywords

ARACHIDONIC ACID; ETHANOLAMINE; GLYCEROPHOSPHOLIPID; LYSOPHOSPHATIDIC ACID; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPASE A2; PHOSPHOLIPID;

ADULT; AGED; ARTICLE; BIOASSAY; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; CROHN DISEASE; DEGRADATION; DIGESTIVE SYSTEM INFLAMMATION; ENTERITIS; FEMALE; HUMAN; HUMAN TISSUE; INTESTINE MUCOSA; INTESTINE ULCER; MALE; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; ULCERATIVE COLITIS;

EID: 0033060619     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350050215     Document Type: Article

References (26)

1. Dawidwicz E. Dynamics of membrane lipid metabolism and turnover. Ann Rev Biochem 1987;56:43-61.
2. Nishida T, Miwa H, Shigimatsu A, et al. Increased arachidonic acid composition of phospholipids in colonic mucosa from patients with active ulcerative colitis. Gut 1987;28:1002-7.
3. Pacheco S, Hillier K, Smith C. Increased arachidonic acid levels in phospholipids of human colonic mucosa in inflammatory bowel disease. Clin Sci 1987;73:361-4.
4. Nakanishi K, Yasugi E, Morita H, et al. Plasmenylethanolamine in human intestinal mucosa detected by an improved method for analysis of phospholipid. Biochem Mol Biol Int 1994;33:457-62.
5. The Phospholipase A2. In: Inoue K, Nozawa Y, editors. Protein, nucleic acids, and enzymes (In Japanese). 1991.36(no3), p. 316-33.
6. Ferraris L, Karmeli F, Eliakim R, et al. Intestinal epithelial cells contribute to the enhanced generation of glatelet activating factor in ulcerative colitis. Gut 1993;34:665-8.
7. Tagesson C, Franzén L, Dahl G, Wastöm B. Lysophosphatidylcholine increases rat ileal permeability to macromolecules. Gut 1985;26:369-77.
8. Lazarow PB, Duve CD. A fatty acyl-CoA oxidizing system in rat liver peroxisomes. Enhancement by clofibrate, a hypolipidemic drug. Proc Natl Acad Sci USA 1976;73:2043-6.
9. Bronfman M, Inestrosa NC, Nervi FO, Leighton F. Acyl-CoA synthetase and the peroxisomal enzymes of β-oxidation in human liver. Biochem J 1984;224:709-20.
10. Hajra AK, Burke CL, Jones CL. Subcellular localization of acyl coenzyme A:dihydroxyacetone phosphate acyltransferase in rat liver peroxisomes. J Biol Chem 1979;254:10896-900.
11. Zoeller RA, Raets CRH. Isolation of animal cell mutants deficient in plasmalogen biosynthesis and peroxime assembly. Proc Natl Acad Sci USA 1986;83:5170-4.
12. Olaison G, Sjordahl R, Taggesson C. Increased phospholipase A2 activity of ileal mucosa in Crohn's disease. Digestion 1988;41:136-41.
13. Almer Ç, Franzéén L, Olaison G, et al. Phospholipase A2 activity of colonic mucosa in patients with ulcerative colitis. Digestion 1991;50:135-41.
14. Gassama-Diagne A, Fauvel J, Chap H. Purification of a new, calcium-independent, high molecular weight phospholipase A2/lysophospholipase (phospholipase B) from guinea pig intestinal brush-border membrane. J Biol Chem 1989;254:9470-5.
15. Minami T, Tojo H, Shinomura Y, et al. Purification and characterization of a phospholipase-A(2) from human ileal mucosa. Biochim Biophys Acta 1993;1170:125-30.
16. Lilja I, Smedh K, Olaison G, et al. Phospholipase A2 gene expression and activity in histologically normal ileal mucosa and in Crohn's ileitis. Gut 1995;37:380-5.
17. Clark JD, Milona N, Knopf JL. Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937. Proc Natl Acad Sci USA 1990;87:7708-12.
18. 2+ -dependent translocation domain with homology to PKC and GAP. Cell 1991;65:1043-51.
19. Bolognese B, McCord M, Marshall L. Differential regulation of elicited peritoneal macrophage 14KDa and 85KDa phospholipase A2 by transforming growth factor-beta. Biochim Biophys Acta Lipids and Lipid Metabolism 1995;1256:201-9.
20. Dennis E, Ackermann E, Deems R, Reynolds L. Multiple forms of phospholipase A2 in macrophages capable of arachidonic acid release for eicosanoid biosynthesis. In: Samuelsson B, editor. Prostaglandins and related compounds (advances in prostaglandin, thromboxane and leukotriene research). Raven Press, 1995, p. 75-80.
21. Hirasawa N, Santini F, Beaven M. Activation of the mitogen-activated protein kinase cytosolic phospholipase A2 pathway in a rat mast cell line-Indications of different pathways for release of arachidonic acid and secretory granules. J Immunol 1995;154:5931-402.
22. Kim DK, Kudo I, Inoue K. Detection in human platelets of phospholipase A2 activity which preferentially hydrolyzes an arachidonyl residue. J Biochem 1988;104:492-4.
23. Kim DK, Kudo I, Inoue K. Purification and characterization of rabbit platelet cytosolic phospholipase A2. Biochim Biophys Acta 1991;1083:80-88.
24. Yoshihara Y, Watanabe Y. Translocation of phospholipase A2 from cytosol to membranes in rat brain induced by calcium ions. Biochem Biophys Res Commun 1990;170:484-0.
25. Ross B, Kim D, Bonventre J, Kish S. Characterization of a novel phospholipase A2 activity in human brain. J Neurochem, 1995;64:2213-21.
26. Gustafsonsvard G, Lilja I, Sjodahl R, Tagesson C. Cytosolic phospholipase A2 and cyclooxygenase-2 mediate release and metabolism of arachidonic acid in tumor necrosis factor-alpha-primed cultured intestinal epithelial cells (INT 407). Scand J Gastroenterol 1995;30:1000-7.