Continuous infusion ceftazidime in intensive care: A randomized controlled trial

Journal of Antimicrobial Chemotherapy

Volumn 43, Issue 2, 1999, Pages 309-311

  Lipman, J ^a   Gomersall, C D ^b   Gin, T ^c   Joynt, G M ^b   Young, R J ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHRISTCHURCH HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE;

ARTICLE; BOLUS INJECTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICAL ILLNESS; DRUG BLOOD LEVEL; HUMAN; INTENSIVE CARE; PHARMACODYNAMICS; RANDOMIZED CONTROLLED TRIAL;

ADULT; CEFTAZIDIME; CEPHALOSPORINS; HUMANS; INFUSIONS, INTRAVENOUS; INTENSIVE CARE; MIDDLE AGED;

EID: 0033059826     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/43.2.309     Document Type: Article

References (10)

1. Mouton, J. W. & den Hollander, J. G. (1994). Killing of Pseudomonas aeruginosa during continuous and intermittent infusion of ceftazidime in an in vitro pharmacokinetic model. Antimicrobial Agents and Chemotherapy 38, 931-6.
2. Vogelman, B. & Craig, W. A. (1986). Kinetics of antimicrobial activity. Journal of Pediatrics 108, 835-40.
3. Fantin, B., Farinotti, R., Thabaut, A. & Carbon, C. (1994). Conditions for the emergence of resistance to cefpirome and ceftazidime in experimental endocarditis due to Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 33, 563-9.
4. Scribner, R. K., Marks, M. I., Weber, A. H., Tarpay, M. M. & Welch, D. F. (1982). Activities of various β-lactams and aminoglycosides, alone and in combination, against isolates of Pseudomonas aeruginosa from patients with cystic fibrosis. Antimicrobial Agents and Chemotherapy 21, 939-43.
5. Young, R. J., Lipman, J., Gin, T., Gomersall, C. D., Joynt, G. M. & Oh, T. E. (1997). Intermittent bolus dosing of ceftazidime in critically ill patients. Journal of Antimicrobial Chemotherapy 40, 269-73.
6. Ayrton, J. (1981). Assay of ceftazidime in biological fluids using high-pressure liquid chromatography. Journal of Antimicrobial Chemotherapy 8, Suppl. B, 227-31.
7. Roosendaal, R., Bakker-Woudenberg, I. A. J. M., van den Berghe-van Raffe, M., Vink-van den Berg, J. C. & Michel, M. F. (1989). Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. European Journal of Clinical Microbiology and Infectious Diseases 8, 878-87.
8. Mouton, J. W., Vinks, A. A. & Punt, N. C. (1997). Pharmacokinetic-pharmacodynamic modeling of activity of ceftazidime during continuous and intermittent infusion. Antimicrobial Agents and Chemotherapy 41, 733-8.
9. Mouton, J. W. & Vinks, A. A. (1996). Is continuous infusion of β-lactam antibiotics worthwhile? - efficacy and pharmacokinetic considerations. Journal of Antimicrobial Chemotherapy 38, 5-15.
10. Charmers, H. F. & Neu, H.C. (1995). Penicillins. In Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases, 4th edn (Mandell, G. L., Bennett, J. E. & Dolin, R., Eds), pp. 234. Churchill Livingstone, Edinburgh.