Abnormal periodic acid-Schiff (PAS)-positive substance in the islets of Langerhans, pituitaries and adrenal glands of 139H scrapie-infected hamsters

Histology and Histopathology

Volumn 14, Issue 3, 1999, Pages 673-678

  Ye, X ^a,c   Scallet, A ^a   Carp, R I ^b  

^a National Center for Toxicological Research   (United States)

^b NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Hamster; Islet of Langerhans; PAS positive substance; Pituitary; Scrapie

Indexed keywords

AMYLOID PROTEIN; CONGO RED; PERIODIC ACID; SCHIFF BASE; THIOFLAVINE;

ADRENAL GLAND; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HAMSTER; HYPOPHYSIS; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; NONHUMAN; PANCREAS ISLET; PERIODIC ACID SCHIFF STAIN; SCRAPIE;

ADRENAL GLANDS; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CRICETINAE; FEMALE; ISLETS OF LANGERHANS; PERIODIC ACID-SCHIFF REACTION; PITUITARY GLAND; PRPSC PROTEINS; SCRAPIE;

ANIMALIA; CRICETINAE; VITIS SP.;

EID: 0033059282     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Bank P. (1990). Amyloid deposits of diabetes spark new interest. J. NIH. Res. 2, 34-35.
2. Carp R.I., Kim Y.S., and Callahan S.M. (1990). Pancreatic lesions and hypoglycemia-hyperinsulinemia in scrapie-injected hamsters. J. Infect. Dis. 161, 462-466.
3. Chandler R.L. (1963). Experimental scrapie in the mouse. Res. Vet. Sci. 4, 276-285.
4. Cooper G.J.S., Day A.J., Willis A.C., Roberts A.N., Reid K.B.M. and Leighton B. (1989). Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus. Biochim. Biophys. Acta 1014, 247-258.