메뉴 건너뛰기




Volumn 288, Issue 2, 1999, Pages 849-857

Oral administration of leflunomide (HWA486) results in prominent suppression of immunoglobulin E formation in a rat type 1 allergy model

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROOROTATE DEHYDROGENASE; HISTAMINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN M; LEFLUNOMIDE; OVALBUMIN; TERIFLUNOMIDE;

EID: 0033058631     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (22)
  • 3
    • 0024250889 scopus 로고
    • Development of autoimmunity in MRL/lpr mice and the effects of drugs on this murine disease
    • Bartlett RR, Popovic S and Raiss RX (1988) Development of autoimmunity in MRL/lpr mice and the effects of drugs on this murine disease. Scand J Rheumatol Suppl 75:290-299.
    • (1988) Scand J Rheumatol Suppl , vol.75 , pp. 290-299
    • Bartlett, R.R.1    Popovic, S.2    Raiss, R.X.3
  • 4
    • 0021957656 scopus 로고
    • Immunopharmacological profile of a novel isoxazol derivative, HWA 486, with potential antirheumatic activity-I. Disease modifying action on adjuvant arthritis of the rat
    • Bartlett RR and Schleyerbach R (1985) Immunopharmacological profile of a novel isoxazol derivative, HWA 486, with potential antirheumatic activity-I. Disease modifying action on adjuvant arthritis of the rat. Int J Immunopharmacol 7:7-18.
    • (1985) Int J Immunopharmacol , vol.7 , pp. 7-18
    • Bartlett, R.R.1    Schleyerbach, R.2
  • 8
    • 0027501428 scopus 로고
    • Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide
    • Mattar T, Kochhar K, Bartlett R, Bremer EG and Finnegan A (1993) Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide. FEBS Lett 334:161-164.
    • (1993) FEBS Lett , vol.334 , pp. 161-164
    • Mattar, T.1    Kochhar, K.2    Bartlett, R.3    Bremer, E.G.4    Finnegan, A.5
  • 10
    • 0028358709 scopus 로고
    • Prevention of the acute graft-versus-host disease (GVHD) in rats by the immunomodulating drug leflunomide
    • Mrowka C, Thoenes GH, Langer KH and Bartlett RR (1994) Prevention of the acute graft-versus-host disease (GVHD) in rats by the immunomodulating drug leflunomide. Ann Hematol 68:195-199.
    • (1994) Ann Hematol , vol.68 , pp. 195-199
    • Mrowka, C.1    Thoenes, G.H.2    Langer, K.H.3    Bartlett, R.R.4
  • 11
    • 0023554171 scopus 로고
    • The use of the murine chronic graft Vs host (CGVH) disease, a model for systemic lupus erythematosus (SLE), for drug discovery
    • Popovic S and Bartlett RR (1987) The use of the murine chronic graft Vs host (CGVH) disease, a model for systemic lupus erythematosus (SLE), for drug discovery. Agents Actions 21:284-286.
    • (1987) Agents Actions , vol.21 , pp. 284-286
    • Popovic, S.1    Bartlett, R.R.2
  • 12
    • 0029743653 scopus 로고    scopus 로고
    • Ganglioside GM3 inhibition of EGF receptor mediated signal transduction
    • Rebbaa A, Hurh J, Yamamoto H, Kersey DS and Bremer EG (1996) Ganglioside GM3 inhibition of EGF receptor mediated signal transduction. Glycobiology 6:399-406.
    • (1996) Glycobiology , vol.6 , pp. 399-406
    • Rebbaa, A.1    Hurh, J.2    Yamamoto, H.3    Kersey, D.S.4    Bremer, E.G.5
  • 13
    • 0028124203 scopus 로고
    • Therapeutic activity of leflunomide in acute and chronic relapsing experimental allergic encephalomyelitis
    • Schorlemmer HU and Bartlett RR (1994) Therapeutic activity of leflunomide in acute and chronic relapsing experimental allergic encephalomyelitis. Agents Actions 41:C271-C273.
    • (1994) Agents Actions , vol.41
    • Schorlemmer, H.U.1    Bartlett, R.R.2
  • 14
    • 0027536435 scopus 로고
    • Prolongation of allogeneic transplanted skin grafts and induction of tolerance by leflunomide, a new immunosuppressive isoxazol derivative
    • Schorlemmer HU, Seiler FR and Bartlett RR (1993) Prolongation of allogeneic transplanted skin grafts and induction of tolerance by leflunomide, a new immunosuppressive isoxazol derivative. Transplant Proc 25:763-767.
    • (1993) Transplant Proc , vol.25 , pp. 763-767
    • Schorlemmer, H.U.1    Seiler, F.R.2    Bartlett, R.R.3
  • 16
    • 0029807651 scopus 로고    scopus 로고
    • Single- and multiple-dose pharmacokinetics and pharmacodynamics of leflunomide's active metabolite A77 1726 in normal Lewis rats
    • Silva HT, Shorthouse R and Morris RE (1996) Single- and multiple-dose pharmacokinetics and pharmacodynamics of leflunomide's active metabolite A77 1726 in normal Lewis rats. Transplant Proc 28:3092-3094.
    • (1996) Transplant Proc , vol.28 , pp. 3092-3094
    • Silva, H.T.1    Shorthouse, R.2    Morris, R.E.3
  • 17
    • 0029134647 scopus 로고
    • Protective effect of leflunomide on the natural course of Leishmania major-induced disease in genetically susceptible BALB/c mice
    • Solbach W, Asmuß PA, Zimmermann S, Humborg C and Röllinghoff M (1995) Protective effect of leflunomide on the natural course of Leishmania major-induced disease in genetically susceptible BALB/c mice. Int J Immunopharmacol 17:481-488.
    • (1995) Int J Immunopharmacol , vol.17 , pp. 481-488
    • Solbach, W.1    Asmuß, P.A.2    Zimmermann, S.3    Humborg, C.4    Röllinghoff, M.5
  • 20
    • 0029052321 scopus 로고
    • Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide
    • Xu X, Williams JW, Bremer EG, Finnegan A and Chong AS-F (1995) Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. J Biol Chem 270:12398-12403
    • (1995) J Biol Chem , vol.270 , pp. 12398-12403
    • Xu, X.1    Williams, J.W.2    Bremer, E.G.3    Finnegan, A.4    Chong, A.S.-F.5
  • 21
    • 0030014489 scopus 로고    scopus 로고
    • Two activities of the immunosuppressive metabolite of leflunomide, A77 1726: Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation
    • Xu X, Williams JW, Gong H, Finnegan A and Chong AS-F (1996) Two activities of the immunosuppressive metabolite of leflunomide, A77 1726: Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation. Biochem Pharmacol 52:527-534.
    • (1996) Biochem Pharmacol , vol.52 , pp. 527-534
    • Xu, X.1    Williams, J.W.2    Gong, H.3    Finnegan, A.4    Chong, A.S.-F.5
  • 22
    • 0029098762 scopus 로고
    • Leflunomide, a reversible inhibitor of pyrimidine biosynthesis?
    • Zielinski T, Zeitter D, Müllner S and Bartlett RR (1995) Leflunomide, a reversible inhibitor of pyrimidine biosynthesis? Inflamm Res 44(Suppl 2):S207-S208.
    • (1995) Inflamm Res , vol.44 , Issue.SUPPL. 2
    • Zielinski, T.1    Zeitter, D.2    Müllner, S.3    Bartlett, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.