Prognostic implications of various models for calculation of S-phase fraction in 259 patients with soft tissue sarcoma

British Journal of Cancer

Volumn 79, Issue 7-8, 1999, Pages 1205-1209

  Gustafson, P ^a   Baldetorp, B ^a   Ferno M ^a   Akerman M ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Background correction; DNA flow cytometry; Prognosis; S phase fraction; Soft tissue sarcoma

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CELL CYCLE S PHASE; COMPUTER MODEL; COMPUTER PROGRAM; DATA BASE; DNA DETERMINATION; FLOW CYTOMETRY; HISTOGRAM; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; METASTASIS; MUSCULOSKELETAL SYSTEM; PRIORITY JOURNAL; PROGNOSIS; RISK; SOFT TISSUE SARCOMA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DISEASE-FREE SURVIVAL; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; S PHASE; SARCOMA;

EID: 0033058013     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690193     Document Type: Article

References (19)

1. Bagwell CB, Mayo SW, Whetstone SD, Hitchcox SA, Baker DR, Herbert DJ, Weawer DL, Jones MA and Lovett EJ III (1991) DNA histogram debris theory and compensation. Cytometry 12: 107-118
2. Baisch H, Gohde W and Linden WA (1975) Analysis of PCP-data to determine the fraction of cells in the various phases of cell cycle. Radiat Environ Biophys 12: 31-39
3. Baldetorp B, Dalberg M, Holst U and Lindgren G (1989) Statistical evaluation of cell kinetic data from DNA flow cytometry (FCM) by the EM algorithm. Cytometry 10: 695-705
4. Baldetorp B, Bendahl P-O, Fernö M, Alanen K, Delle U, Falkmer U, Hansson-Aggesjö B, Höckenström T, Lindgren A, Mossberg L, Nordling S, Sigurdsson H, Stål O and Visakorpi T (1995) Reproducibility in DNA flow cytometric analysis of breast cancer: comparison of 12 laboratories results for 67 sample homogenates. Cytometry 22: 115-127
5. Baldetorp B, Stål O, Ahrens O, Cornelisse C, Corwer W, Falkmer U and Fernö M (1998) Different calculation methods for flow cytometric S-phase fraction: prognostic implications in breast cancer? Cytometry 33: 385-393
6. Beck HP (1980) Evaluation of flow cytometric data of human tumours. Correction procedures for background and cell aggregates. Cell Tissue Kinet 13: 173-181
7. Bratl O, Andersson H, Bak-Jensen E, Baldetorp B and Lundgren R (1996) Metaphase cytogenetics and DNA flow cytometry with analysis of S-phase fraction in prostate cancer: influence on prognosis, Urology 47: 218-224
8. Collin F, Chassevent A, Bonichon F, Bertrand G, Terrier P and Coindre J-M (1997) Flow cytometric DNA content analysis of 185 soft tissue neoplasms indicates that S-phase fraction is a prognostic factor for sarcomas. Cancer 79: 2371-2379
9. Gudmundsson TE, Högberg T, Alm P, Anderson H, Baldetorp B, Fernö M, Långström E and Killander D (1995) The prognostic information of DNA ploidy and S-phase fraction may vary with histologic grade in endometrial carcinoma. Acta Oncologica 34: 803-812
10. Gustafson P (1994) Soft tissue sarcoma. Epidemiology and prognosis in 508 patients. Acta Orthop Scand 65 (suppl 259): 1-31
11. Gustafson P, Fernö M, Åkerman M, Baldetorp B, Willén H, Killander D and Rydholm A (1997) Flow cytometric S-phase fraction in soft-tissue sarcoma: prognostic importance analysed in 160 patients. Br J Cancer 75: 94-100
12. Huuhtanen R, Blomqvist C, Wiklund T, Virolainen M, Elomaa I, Pan Y and Tribukait B (1996) S-phase fraction of 155 soft tissue sarcomas. Correlation with clinical outcome. Cancer 77: 1815-1822
13. Marquardt DW (1963) An algoritm for least-squares estimation of nonlinear parameters. Soc Ind Appl Math 11: 431-441
14. Merkel DE and McGuire WL (1990) Ploidy, proliferative activity and prognosis. DNA flow cytometry of solid tumours. Cancer 65: 1194-1205
15. Rabinovitch PS (1991) Numerical compensation for the effects of cell clumping on DNA content histograms. Cytometry 4(suppl): 27
16. Schutte B, Reynders MMJ, Bosman FT and Blijham GH (1985) Flow symmetric determination of DNA ploidy level in nuclei isolated from paraffin-embedded tissue. Cytometry 6: 26-30
17. Shankey TV, Rabinovitch PS, Bagwell B, Bauer KD, Duque RE, Hedley DW, Mayall BH and Wheeless L (1993) Guidelines for implementation of clinical DNA cytometry. Cytometry 14: 472-477
18. Sigurdsson H, Baldetorp B, Borg Å, Dalberg M, Fernö M, Killander D and Olsson H (1990) Indicators of prognosis in node-negative breast cancer. N Engl J Med 322: 1045-1053
19. Stål O and Baldetorp B (1998) S-phase fraction assessed by a variant of the rectangular model adapted to the flowcytometric DNA histogram profile. Cytometry 33: 487-491