Neurotensin stimulation of mast cell secretion is receptor-mediated, pertussis-toxin sensitive and requires activation of phospholipase C

Immunopharmacology

Volumn 41, Issue 2, 1999, Pages 131-137

  Barrocas, Alex M ^a   Cochrane, David E ^a   Carraway, Robert E ^b   Feldberg, Ross S ^a  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Mast cell; Neurotensin; Neurotensin receptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 [[1 (7 CHLORO 4 QUINOLINYL) 5 (2,6 DIMETHOXYPHENYL) 3 PYRAZOLYL]CARBONYLAMINO] 2 ADAMANTANECARBOXYLIC ACID; CELL RECEPTOR; COMPOUND 48-80; INOSITOL TRISPHOSPHATE; MASTOPARAN; NEUROTENSIN; NEUROTENSIN RECEPTOR ANTAGONIST; PERTUSSIS TOXIN; PHOSPHOLIPASE C; SUBSTANCE P;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HISTAMINE RELEASE; MALE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ENZYME ACTIVATION; ESTRENES; HISTAMINE RELEASE; MALE; MAST CELLS; NEUROTENSIN; PERTUSSIS TOXIN; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C; PYRAZOLES; PYRROLIDINONES; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROTENSIN; STIMULATION, CHEMICAL; SUBSTANCE P; VIRULENCE FACTORS, BORDETELLA;

EID: 0033057942     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(98)00064-2     Document Type: Article

References (40)

1. Aridor M., Rajmilevich G., Beaver M.A., Sagi-eisenberg R. Activation of exocytosis by the heterotrimeric G protein Gi3. Science. 262:1993;1569-1572.
2. Aridor M., Traub L.M., Sagi-eisenberg R. Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins. J. Cell Biol. 111:1990;909-917.
3. Bibb P.C., Cochrane D.E. Replenishment of the cellular calcium required for non-immunologic stimulation of mast cell histamine secretion: temperature sensitivity and inhibition of manganese and sodium-free conditions. Agents Actions. 25:1988;27-36.
4. Bleasdale J.E., Thakur N.R., Gremban R.S., Bundy G.L., Fitzpatrick F.A., Smith R.J., Bunting S. Selective inhibition of receptor-coupled phospholipase c-dependent processes in human platelets and polymorphonuclear neutrophils. J. Pharmacol. Exp. Ther. 255:1990;756-768.
5. Carraway, R.E., 1989. Neurotensin. In: Becker K (Ed.), Principles and Practice of Endocrinology and Metabolism. J.B. Lippincott, Philadelphia, Vol. 1, pp. 1303-1307.
6. Carraway R.E., Cochrane D.E., Boucher W., Mitra S.P. Structure and biological activity of histamine-releasing peptide (HRP) generated from albumin by acid proteases. J. Immunol. 143:1989;1680-1684.
7. Carraway R.E., Cochrane D.E., Lansman J.B., Leeman S.E., Paterson B.M., Welch H.J. Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels. J. Physiol. 323:1982;403-414.
8. Chapman D.E. Calcium signaling. Cell. 80:1995;259-268.
9. Cochrane, D.E., 1990. Peptide regulation of mast-cell function. In: Ellis, G.P., West, G.B. (Eds.), Progress in Medicinal Chemistry. Elsevier, London, Vol. 27. pp. 143-188.
10. Cochrane D.E., Carraway R.E., Boucher W., Feldberg R.S. Rapid degradation of neurotensin by stimulated rat mast cells. Peptides. 12:1991;1187-1194.
11. Devillier P., Renoux M., Giroud J.P., Regoli D. Peptides and histamine release from rat peritoneal mast cells. Eur. J. Pharmacol. 117:1985;89-96.
12. Evers M., Bold R.J., Ehrenfried J.A., LI J., Townsend C.M., Klimpel G.R. Characterization of functional neurotensin receptors on human lymphocytes. Surgery. 116:1994;134-140.
13. Feldberg R.S., Cochrane D.E., Carraway R.E., Brown E.M., Sawyer R., Hartunian M., Wentworth D.B. Evidence for a neurotensin receptor in rat serosal mast cells. FASEB J. 11:1997;A914.
14. Ferris, C.F., 1989. Neurotensin. In: Schultz, S.G., Makhlouf, G.M. (Eds.), Handbook of Physiology, Section 6, the Gastrointestinal System II. Oxford Univ. Press, New York, pp. 559-586.
15. Fernstrom, M.H., Carraway, R., Leeman, S.E., 1980. Neurotensin. In: Martini, L. (Ed.), Frontiers in Neuroendocrinology. Raven Press, New York, Vol. 6, pp. 103-27.
16. 4] neurotensin. Proc. Natl. Acad. Sci. U.S.A. 73:1976;3833-3837.
17. Goldman R., Bar-shavit Z., Shezen Z., Blumberg S. Enhancement of phagocytosis by neurotensin, a newly found biological activity of the neuropeptide. Adv. Exp. Med. Biol. 155:1982;41-133.
18. Goldstein, S.M., Wintroub, B.U., 1993. Mast cell proteases. In: Kaliner, M.A., Metcalfe, D.M. (Eds.), The Mast Cell in Health and Disease. Marcel Dekker, New York, Chap. 12, pp. 343-380.
19. Gully D., Canton M., Boigegrain R., Jeanjean F., Molimard J.-C., Poncelet M., Cuiudet C., Heaulme M., Leyris R., Brouard A., Pelaprat D., Labbé-jullié C., Mazella J., Soubrie P., Maffrand J.-P., Rostene W., Kitabgi P., Lefur G. Biochemical and pharmacologic profile of a potent and selective nonpeptide antagonist of the neurotensin receptor. Proc. Natl. Acad. Sci. U.S.A. 90:1993;65-69.
20. Hartung H.P. Activation of macrophages by neuropeptides. Brain Behav. Immun. 2:1988;81-275.
21. 2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production. Endocrinology. 130:1992;3475-3483.
22. Koff W.C., Dunegan M.A. Modulation of macrophage-mediated tumoricidal activity by neuropeptides and neurohormones. J. Immunol. 135:1985;350-354.
23. Lemaire I. Neurotensin enhances IL-1 production by activated alveolar macrophages. J. Immunol. 140:1988;9-2983.
24. Miller L.A., Cochrane D.E., Carraway R.E., Feldberg R.S. Blockade of mast cell histamine secretion in response to neurotensin by SR 48692, a nonpeptide antagonist of the neurotensin brain receptor. Br. J. Pharmacol. 114:1995;. in press.
25. 2+ release and directly activates ion channels in mouse pancreatic acinar cells. Biochem. J. 324:1997;645-651.
26. Mousli M., Bronner C., Bueb J.-L., Tschirhart E., Gies J.P., Landry Y. Activation of rat peritoneal mast cells by substance P and mastoparan. J. Pharmacol. Exp. Ther. 250:1989;329-335.
27. Mousli M., Bueb J.-L., Bronner C., Rouot B., Landry Y. G-protein activation: a receptor-independent mode of action for cationic amphophilic neuropeptides and venom peptides. Trends Pharmacol. Sci. 11:1990;358-362.
28. Mousli M., Hugli T.E., Landry Y., Bronner C. Peptidergic pathway in human skin and rat peritoneal mast cell activation. Immunopharmacology. 27:1994;1-11.
29. Nakamura T., Ui M. Simultaneous inhibitions of inositol phospholipase breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. J. Biol. Chem. 260:1985;3584-3593.
30. Prange A.J. Jr. The manifold actions of neurotensin, a trophotropic agent. New York Acad. Sci. 668:1992;298-306.
31. Rosengard B.R., Mahalik C., Cochrane D.E. Mast cell secretion: differences between immunologic and non-immunologic stimulation. Agents Actions. 19:1986;40-133.
32. Saito H., Okajima F., Molski T.F.P., Sha'afi R.I., Vi M., Ishizaka T. Effects of ADP-ribosylation of GTP-binding protein by pertussis toxin on immunoglobulin E-dependent and independent histamine release from mast cells and basophils. J. Immunol. 138:1987;3927-3934.
33. Schaeffer P., Laplace M.-C., Savi P., Pflieger A.-M., Gully D., Herbert J.-M. Human umbilical vein endothelial cells express high affinity neurotensin receptors coupled to intracellular calcium release. J. Biol. Chem. 270:1995;3409-3413.
34. 3 rat pituitary cells. Endocrinology. 131:1992;1883-1888.
35. Snider R.M., Forray C., Pfenning M., Richelson E. Neurotensin stimulates inositol phospholipid metabolism and calcium mobilization in murine neuroblastoma clone NIE-115. J. Neurochem. 47:1986;1214-1218.
36. Yamada M., Yamada M., Richelson E. Block of neurotensin receptor down-regulation by an aminosteroid in NIE-115 cells. Eur. J. Pharmacol. 226:1992;187-188.
37. Yamada M., Yamada M., Watson M.A., Richelson E. Deletion mutation in the putative third intracellular loop of the rat neurotensin receptor abolishes polyphosphoinositide hydrolysis but not cyclic AMP formation in CHO-Kl cells. Mol. Pharmacol. 46:1994;470-476.
38. 2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells. J. Biol. Chem. 287:1992;13830-13855.
39. Wasserman, S.I, Marquardt, D.L., Barrett, K.E., 1993. Mechanisms of mast cell signaling. In: Brody, J.S., Center, D.M., Tkachuk, V.A., (Eds.), Signal Transduction in Lung Cells. Marcel Dekker, New York, Chap. 24, pp. 541-554.
40. Watson M.A., Yamada M., Yamada M., Cosack B., Veverka K., Bolden-Watson C., Richelson E. The rat neurotensin receptor expressed in Chinese hamster ovary cells mediates the release of inositol phosphates. J. Neurochem. 59:1992;1967-1970.