A molecular-field-based similarity study of non-nucleoside HIV-1 reverse transcriptase inhibitors

Journal of Computer-Aided Molecular Design

Volumn 13, Issue 1, 1999, Pages 79-93

  Mestres, Jordi ^a,b   Rohrer, Douglas C ^a   Maggiora, Gerald M ^a  

^a P ^*  (United States)

^b NV ORGANON   (Netherlands)

Author keywords

Molecular alignments; Molecular field similarity; Non nucleoside HIV 1 reverse transcriptase inhibitors; Pharmacophore patterns; Protein structure alignments

Indexed keywords

BIOMOLECULES; CHAINS; CRYSTAL ORIENTATION; PHARMACODYNAMICS; PROTEINS; QUALITY CONTROL;

EXPERIMENTAL MODELLING; HIV-1 REVERSE TRANSCRIPTASE; MATCHINGS; MOLECULAR FIELDS; MOLECULAR-FIELD SIMILARITY; NON-NUCLEOSIDE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR; PAIRWISE ALIGNMENT; PHARMACOPHORE PATTERN; PHARMACOPHORES; PROTEIN STRUCTURE ALIGNMENT;

MOLECULES;

ACETANILIDE DERIVATIVE; NEVIRAPINE; PROTEIN SUBUNIT; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE INHIBITOR; TIVIRAPINE; ZINC FINGER PROTEIN;

ARTICLE; COMPUTER PROGRAM; CRYSTAL STRUCTURE; DRUG DESIGN; LIGAND BINDING; MOLECULAR MIMICRY; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN TARGETING; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

EID: 0033057407     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008098215954     Document Type: Article

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