Dose independent pharmacokinetics of caffeine after intravenous administration under a chronic food-limited regimen

Drug Metabolism and Drug Interactions

Volumn 15, Issue 1, 1999, Pages 83-96

  Smith, Curtis ^a,c   Ma, Fang ^b   Lau, Chyan E ^b  

^a FERRIS STATE UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c Claire Dart Stroke Center Sparrow Hospital   (United States)

Author keywords

Caffeine; Cytochrome P450; Dimethylxanthine metabolites; Pharmacokinetics

Indexed keywords

CAFFEINE; DRUG METABOLITE; METHYLXANTHINE DERIVATIVE; PARAXANTHINE; THEOBROMINE; THEOPHYLLINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; DIET RESTRICTION; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; FOOD DRUG INTERACTION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN RESIDENCE TIME; NONHUMAN; PHARMACOKINETICS; RAT; REVIEW;

EID: 0033056933     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: 10.1515/DMDI.1999.15.1.83     Document Type: Review

References (20)

1. Gilbert RM. Caffeine as a drug of abuse. In. Gibbon RJ, Israel Y, Kalant M, Poplan RE, Schmidt W, Smart RG, eds Research Advances in Alcohol and Drug Problems. Vol. 3, New York: John Wiley & Sons, 1976; 49-176.
2. Schreiber GB, Maffeo CE, Robins M, et al. Measurement of coffee and caffeine intake: implications for epidemiological research. Prev Med 1988; 17: 280-294.
3. Nehlig A, Daval J-L, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Rev 1992; 17: 139-170.
4. Griffiths RR, Woodson PP, Caffeine physical dependence: a review of human and laboratory studies. Psychopharmacology 1988; 94: 437-451.
5. Pincomb GA, Lovallo WR, Passey RB, Wilson MF. Effect of behavior state on caffeine's ability to alter blood pressure. Am J Cardiol 1988; 61: 798-802.
6. Somani SM, Gupta P, Caffeine: a new look at an age-old drug. Int J Clin Pharmacol Ther Toxicol 1988; 26: 521-533.
7. Tassaneeyakul W, Birkett DJ, McManus ME, et al. Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms. Biochem Pharmacol 1994; 47: 1767-1776.
8. Bonati M, Gaxattini S. Interspecies composition of caffeine disposition. In: Dews PB, ed. Caffeine. New York: Springer-Verlag, 1984: 48-56.
9. Tang-Liu DD, Williams RL, Riegelman S. Disposition of caffeine and its metabolites in man. J Pharmacol Exp Ther 1983; 224: 180-185.
10. Latini R, Bonati M, Castelli D, Garattini S. Dose-dependent kinetics of caffeine in rats. Toxicol Lett 1978; 2: 267-270.
11. 1 adenosine receptor binding. J Pharmacol Exp Therap 1993; 266: 1563-1572.
12. Denaro CP, Brown CR, Wilson M, Jacob P, Benowitz NL. Dose-dependency of caffeine metabolism with repeated dosing. Clin Pharmacol Ther 1990; 48: 277-285.
13. Cheng WSC, Murphy TL, Smith MT, Cooksley WGE, Halliday JW, Powell LW Dose-dependent pharmacokinetics of caffeine in humans: relevance as a test of quantitative liver function. Clin Pharmacol Ther 1990; 47: 516-524.
14. Lau CE, Ma F, Falk JL. Oral and IP caffeine pharmacokinetics under a chronic food-limitation condition. Pharmacol Biochem Behav 1995; 50: 245-252.
15. Lau CE, Ma F, Wang Y, Smith C. Pharmacokinetics and bioavailability of midazolam after intravenous, subcutaneous, intraperitoneal and oral administration under a chronic food-limited regimen: relating DRL performance to pharmacokinetics. Psychopharmacology 1996; 126: 241-248.
16. Lau CE, Falk JL. Sustained synergism by chronic caffeine of the motor control deficit produced by midazolam. Pharmacol Biochem Behav 1991; 40: 723-731.
17. Parke D, Ioannides C. The effects of nutrition on chemical toxicity. Drug Metab Rev 1994; 26: 739-765.
18. Leakey JA, Cunny HC, Bazare J, et al. Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system. Mech Ageing Dev 1989; 48: 145-155.
19. Hong J, Pan J, Gonzalez FJ, Gelboin HV, Yang CS. The induction of a specific form of cytochrome P-450 (P-450j) by fasting. Biochem Biophys Res Comm 1987; 142: 1077-1083.
20. Sachan DS. Modulation of drug metabolism by food restriction in male rats. Biochem Biophys Res Comm 1982; 104: 984-989.