Characterization of three-dimensional tissue cultures using electrical impedance spectroscopy

Biophysical Journal

Volumn 76, Issue 5, 1999, Pages 2640-2648

  Kyle, Alastair H ^a   Chan, Carmel T O ^a   Minchinton, Andrew I ^a  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INULIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; DIFFUSION; ELECTRIC MODEL; HUMAN; HUMAN CELL; IMPEDANCE; MEASUREMENT; NONHUMAN; SPECTROSCOPY; TISSUE CULTURE;

EID: 0033056629     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(99)77416-3     Document Type: Article

References (30)

1. Ackmann, J. J. 1993. Complex bioelectric impedance measurement system for the frequency range from 5 Hz to 1 MHz. Ann. Biomed. Eng. 21:135-146.
2. Bao, J. Z., C. C. Davis, and R. E. Schmukler. 1993. Impedance spectroscopy of human erythrocytes: system calibration and nonlinear modeling. IEEE Trans. Biomed. Eng. 40:364-378.
3. Casciari, J. J., S. V. Sotirchos, and R. M. Sutherland. 1988. Glucose diffusivity in multicellular tumor spheroids. Cancer Res. 48:3905-3909.
4. Cole, K. S., and R. H. Cole. 1941. Dispersion and absorption in dielectrics. I. Alternating current characteristics. J. Chem. Phys. 9:341-351.
5. Cowan, D. S. M., K. O. Hicks, and W. R. Wilson. 1996. Multicellular membranes as an in vitro model for extravascular diffusion in tumors. Br. J. Cancer. 74:S28-S31.
6. Crank, J. 1975. The Mathematics of Diffusion. Clarendon Press, Oxford.
7. Durand, R. E. 1980. Variable radiobiological responses of spheroids. Radiat. Res. 81:85-99.
8. Durand, R. E. 1981. Flow cytometry studies of intracellular adriamycin in multicell spheroids in vitro. Cancer Res. 41:3495-3498.
9. Durand, R. E., and P. L. Olive. 1992. Evaluation of bioreductive drugs in multicell spheroids. Int. J. Radiat. Oncol. Biol. Phys. 22:689-692.
10. Foster, K. R., and H. P. Schwan. 1989. Dielectric properties of tissues and biological materials: a critical review. Crit. Rev. Biomed. Eng. 17: 25-104.
11. Freyer, J. P., and R. M. Sutherland. 1983. Determination of diffusion constants for metabolites in multicell tumor spheroids. Adv. Exp. Med. Biol. 159:463-475.
12. Freyer, J. P., E. Tustanoff, A. J. Franko, and R. M. Sutherland. 1984. In situ oxygen consumption rates of cells in V-79 multicellular spheroids during growth. J. Cell. Physiol. 118:53-61.
13. Hicks, K. O., S. J. Ohms, P. L. van Zijl, W. A. Denny, P. J. Hunter, and W. R. Wilson. 1997. An experimental and mathematical model for the extravascular transport of a DNA intercalator in tumors. Br. J. Cancer. 76:894-903.
14. Jain, R. K. 1987. Transport of molecules in the tumor interstitium: a review. Cancer Res. 47:3039-3051.
15. Kerr, D. J., and S. B. Kaye. 1987. Aspects of cytotoxic drug penetration, with particular reference to anthracyclines. Cancer Chemother. Pharmacol. 19:1-5.
16. Kerr, D. J., T. E. Wheldon, A. M. Kerr, and S. B. Kaye. 1987. In vitro chemosensitivity testing using the multicellular tumor spheroid model. Cancer Drug Delivery. 4:63-73.
17. Kobayashi, H., S. Man, C. H. Graham, S. J. Kapitain, B. A. Teicher, and R. S. Kerbel. 1993. Acquired multicellular-mediated resistance to alkylating agents in cancer. Proc. Natl. Acad. Sci. USA. 90:3294-3298.
18. Kwok, T. T., and R. M. Sutherland. 1991. The influence of cell-cell contact on radiosensitivity of human squamous carcinoma cells. Radiat. Res. 126:52-57.
19. Kyle, A., and A. I. Minchinton. 1999. Measurement of delivery and metabolism of tirapazamine through tumor tissue using the multilayered cell culture model. Cancer Chemother. Pharmacol. 43:213-220.
20. McRae, D. A., M. A. Esrick, and S. C. Mueller. 1997. Non-invasive, in-vivo electrical impedance of EMT-6 tumors during hyperthermia: correlation with morphology and tumor-growth-delay. Int. J. Hyperthermia. 13:1-20.
21. Minchinton, A. I., K. R. Wendt, K. A. Clow, and K. H. Fryer. 1997. Multilayers of cells growing on a permeable support: an in vitro tumor model. Acta Oncologica. 36:13-16.
22. Mueller-Klieser, W. 1997. Three-dimensional cell cultures: from molecular mechanisms to clinical applications. Am. J. Physiol. 273:C1109-C1123.
23. Nederman, T., J. Carlsson, and M. Malmqvist. 1981. Penetration of substances into tumor tissue: a methodological study on cellular spheroids. In Vitro. 17:290-298.
24. Nicholson, C., and J. M. Phillips. 1981. Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum. J. Physiol. 321:225-257.
25. Olive, P. L., and R. E. Durand. 1994. Drug and radiation resistance in spheroids: cell contact and kinetics. Cancer Metast. Rev. 13:121-138.
26. Pethig, R. 1979. Dielectric and Electronic Properties of Biological Materials. John Wiley and Sons, New York.
27. Press, W. H. 1992. Numerical Recipes in C: The Art of Scientific Computing. Cambridge University Press, Cambridge.
28. Rigaud, B., J. P. Morucci, and N. Chauveau. 1996. Bioelectrical impedance techniques in medicine. Part I: Bioimpedance measurement. Second section: impedance spectrometry. Crit. Rev. Biomed. Eng. 24:257-351.
29. Schwan, H. P. 1963. Determination of biological impedances. In Physical Techniques in Biological Research. Academic Press, New York. 323-406.
30. Sutherland, R. M. 1988. Cell and environment interactions in tumor microregions: the multicell spheroid model. Science. 240:177-184.