Effects of quinapril and losartan on insulin sensitivity in genetic hypertensive rats with different metabolic abnormalities

Journal of Cardiovascular Pharmacology

Volumn 34, Issue 1, 1999, Pages 28-33

  Nakagawa, Haruto ^a   Daihara, Mitsuko ^a   Tamakawa, Hiroki ^a   Nozue, Taeko ^a   Kawahara, Kiminori ^a  

^a Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

Dahl salt sensitive rats; Insulin sensitivity; Losartan; Quinapril; Spontaneously hypertensive rats

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; HUMAN INSULIN; ICATIBANT; INSULIN; LOSARTAN POTASSIUM; QUINAPRIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ESSENTIAL HYPERTENSION; HEREDITARY HYPERTENSION; INSULIN SENSITIVITY; MALE; METABOLIC DISORDER; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

ADRENERGIC BETA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD CHEMICAL ANALYSIS; BLOOD PRESSURE; BRADYKININ; DRUG RESISTANCE; DRUG SYNERGISM; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HYPERTENSION; INSULIN; ISOQUINOLINES; LOSARTAN; MALE; RATS; RATS, INBRED SHR; TETRAHYDROISOQUINOLINES;

EID: 0033056519     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199907000-00005     Document Type: Article

References (31)

1. Pollare T, Lithell H, Berne C. A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med 1989;321:868-73.
2. Paolisso G, Gamardella A, Verza M. ACE inhibition improves insulin-sensitivity in aged insulin-resistant hypertensive patients. J Hum Hypertens 1992;6:175-9.
3. Tomiyama H, Kushiro T, Abeta H, et al. Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor. Hypertension 1994;23:450-5.
4. Chow L, Gasparo MD, Levens N. Blockade of angiotensin converting enzyme but not of angiotensin AT1 receptors improves glucose tolerance. Eur J Pharmacol 1997;319:77-83.
5. Iimura O, Shimamoto K, Matsuda K, et al. Effects of angiotensin receptor antagonist and angiotensin converting enzyme inhibitor on insulin sensitivity in fructose-fed hypertensive rats and essential hypertensives. Am J Hypertens 1995;8:353-7.
6. Chen S, Kashiwabara H, Kosegawa I, Ishii J, Katayama S. Bradykinin may not be involved in improvement of insulin resistance by angiotensin converting enzyme inhibitor. Clin Exp Hypertens 1996;18:625-36.
7. Shimamoto K, Matsuda K, Takizawa H, Higashiura K, Ura N, Iimura O. Effects of an angiotensin II receptor antagonist, TCV-116, on insulin sensitivity in fructose-fed rats. Blood Pressure 1994;3(Suppl 5):113-6.
8. Reaven GM. Role of insulin resistance in human disease. Diabetes 1988;37:1595-607.
9. Kaplan NM. The deadly quartet: upperbody obesity, glucose intolerance in hypertriglycemia and hypertension. Arch Intern Med 1989;149:1514-20.
10. DeFronzo RA, Ferrannini E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991;14:173-94.
11. Modan M, Or J, Karasik A, et al. Hyperinsulinemia, sex and risk of atherosclerotic cardiovascular disease. Circulation 1991;84: 1165-75.
12. Ferrannini E, Buzzigoli G, Bonnadonna R, et al. Insulin resistance in essential hypertension. N Engl J Med 1987;317:350-7.
13. Reaven GM. Insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension: parallels between human disease and rodent models. Diabetes Care 1991;14:195-202.
14. Bursztyn M, Ben ID, Gutman A. Insulin resistance in spontaneously hypertensive rats but not in deoxycorticosterone-salt or renal vascular hypertension. J Hypertens 1992;10:137-42.
15. Dubey RK, Zhang HY, Reddy SR, Boegehold MA, Kotchen TA. Pioglitazone attenuates hypertension and inhibits growth of renal arteriolar smooth muscle in rats. Am J Physiol 1993;265:R726-32.
16. Reaven GM, Chang H. Relationship between blood pressure, plasma insulin and triglyceride concentration, and insulin action in spontaneous hypertensive and Wistar-Kyoto rats. Am J Hypertens 1991;4:34-8.
17. Reaven GM, Twersky J, Chang H. Abnormalities of carbohydrate and lipid metabolism in Dahl rats. Hypertension 1991;18:630-5.
18. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214-23.
19. Torlone E, Rambotti AM, Perriello G. ACE-inhibition increases hepatic and extrahepatic sensitivity to insulin in patients with type 2 (non-insulin-dependent) diabetes mellitus and arterial hypertension. Diabetologia 1991;34:119-25.
20. Donnelly R. Angiotensin-converting enzyme inhibitors and insulin sensitivity: metabolic effects in hypertension, diabetes, and heart failure. J Cardiovasc Pharmacol 1992;20(Suppl 11):S38-44.
21. Rett K, Wicklmayr M, Dietze GJ, Haring HU. Insulin-induced glucose transporter (GLUT1 and GLUT4) translocation in cardiac muscle tissue is mimicked by bradykinin. Diabetes 1996;45(Suppl 1):S66-9.
22. Uehara M, Kishikawa H, Isami S, et al. Effect on insulin sensitivity of angiotensin converting enzyme inhibitors with or without a sulphydryl group: bradykinin may improve insulin resistance in dogs and humans. Diabetologia 1994;37:300-7.
23. Liu YH, Yang XP, Sharov VG, et al. Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. J Clin Invest 1997;99:1926-35.
24. 2-receptor activation, bradykinin and prostaglandins in pigs. J Am Coll Cardiol 1998;32:1787-96.
25. Erlich Y, Rosenthal T. Contribution of bradykinin to the beneficial effects of ramipril in the fructose-fed rat. J Cardiovasc Pharmacol 1998;31:581-4.
26. McGiff JC, Terragno NA, Malik KU, Lonigro AJ. Release of a prostaglandin E-like substance from canine kidney by bradykinin. Circ Res 1972;31:36-43.
27. Dyer SM, Frewin DB, Head RJ. The influence of chronic captopril treatment and its withdrawal on endothelium-dependent relaxation. Blood Pressure 1997;1:247-53.
28. Henriksen EJ, Jacob S, Augustin HJ, Dietze GJ. Glucose transport activity in insulin-resistant rat muscle. Diabetes 1996;45(Suppl 1):S125-8.
29. Kishi K, Muromoto N, Nakaya Y, et al. Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway. Diabetes 1998;47:550-8.
30. Carvalho CRO, Thirone ACP, Gontijo JAR, Velloso LA, Saad MJA. Effect of captopril, losartan and bradykinin on early steps of insulin action. Diabetes 1997;46:1950-7.
31. Bevilacqua S, Buzzigoli G, Bonadonna R, et al. Operation of Randle's cycle in patients with NIDDM. Diabetes 1990;39:383-9.