Involvement of protein kinase A in histamine-mediated inhibition of IL-2 mRNA expression in mouse splenocytes

Immunopharmacology

Volumn 41, Issue 2, 1999, Pages 77-87

  Poluektova, Larisa Y ^a   Huggler, Gregory K ^a   Patterson, Eric B ^a   Khan, Manzoor M ^a  

^a CREIGHTON UNIVERSITY   (United States)

Author keywords

Histamine; Interleukin 2; Protein kinase A; Rp cAMPS

Indexed keywords

ADENOSINE 3',5' PHOSPHOROTHIOATE; CD3 ANTIGEN; CHOLERA TOXIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTAMINE; INTERLEUKIN 2; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES; ANTIGENS, CD3; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTAMINE; INTERLEUKIN-2; IONOMYCIN; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; THIONUCLEOTIDES;

EID: 0033055389     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(98)00057-5     Document Type: Article

References (32)

1. Anastassiou E.D., Paliogianni F., Balow J.P., Yamado H., Boumpas D.T. Prostaglandin E2 and other cyclic AMP-elevating agents modulate IL-2 and IL-2Ra gene expression at multiple levels. J. Immunol. 141(9):1992;2845-2852.
2. Arad G., Nussinovich R., Na'amad M., Kaempfer R. Dual control of human interleukin-2 and interferon-gamma gene expression by histamine: activation and suppression. Cell. Immunol. 170(1):1996;149-155.
3. Averill et al., 1988.
4. Carlsson R., Dohlsten M., Sjogren H.O. Histamine modulates the production of interferon-gamma and interleukin-2 by mitogen-activated human mononuclear blood cells. Cell. Immunol. 96(1):1985;104-112.
5. Diverse-Pierlussi M., Remmers A.E., Neubig R.R., Dunlap K. Novel form of crosstalk between G protein and tyrosine kinase pathways. Proc. Natl. Acad. Sci. USA. 10:1997;5417-5421.
6. Dohlsten M., Sjogren H.O., Carlsson R. Histamine acts directly on human T cells to inhibit interleukin-2 and interferon-gamma production. Cell. Immunol. 109(1):1987;65-74.
7. Fraser J.D., Straus D., Weiss A. Signal transduction events leading to T-cell lymphokine gene expression. Immunol. Today. 14:1993;357-362.
8. Hol B.E., Krouwels F.H., Bruinier B., Lutter R., Bast A., Wierenga E.A., Jansen H.M., Out T.A. Heterogeneous effects of histamine on proliferation of lung- and blood-derived T-cell clones from healthy and asthmatic persons. Am. J. Respir. Cell. Mol. Biol. 8(6):1993;647-654.
9. Kammer G.M. The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. Immunol. Today. 9(7-8):1988;222-229.
10. Khan M.M., Melmon K.L., Fathman C.G., Hertel-Wulff B., Strober S. The effects of autacoids on cloned murine lymphoid cells: modulation of IL-2 secretion and the activity of natural suppressor cells. J. Immunol. 134:1985;4100-4106.
11. Kvanta A., Nordstedt C., Jondal M., Fredholm B.B. Activation of protein kinase C via the T-cell receptor complex potentiates cyclic AMP responses in T-cells. Naunyn-Schmiedebergs. Arch. Pharmacol. 340:1989;715-717. 6pt2.
12. Lacour M., Arrighi J.F., Muller K.M., Calberg C., Saurat J.H., Hauser C. cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction. Int. Immunol. 6(9):1994;1333-1343.
13. Laxminarayana D., Kammer G.M. Activation of type I protein kinase during receptor-mediated human T lymphocyte activation. J. Immunol. 156:1996;497-506.
14. Lee H.J., Koyano-Nakagawa N., Naito Y., Nishida J., Arai N., Arai K., Yokota T. cAMP activates the ester through the signaling pathway involving protein kinase A in mouse thymoma line EL-4. J. Immunol. 151(11):1993;6135-6142.
15. Lee H.J., Matsuda I., Naito Y., Takashi Y., Arai N., Arai K. Signals and nuclear factors that regulate the expression of interleukin-4 and interleukin-5 genes in helper T cells. J. Allergy Clin. Immunol. 94:1994;594-604. 3, p. 2.
16. Lohmann S.M., Walter U. Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases. Adv. Cyclic Nucleotide Protein Phosphorylation Res. 18:1984;63-117.
17. Mary D., Aussel C., Ferrula B., Fehlmann M. Regulation of interleukin-2 synthesis by cAMP in human T cells. J. Immunol. 139(4):1987;1179-1184.
18. Munoz E., Zubiaga A.M., Munoz J., Huber B.T. Regulation of IL-4 lymphokine gene expression and cellular proliferation in murine T helper type II cells. Cell Regulation. 1(5):1990;425-434.
19. Novak T.J., Rothenberg E.V. cAMP inhibits induction of interleukin-2 but not of interleukin-4 in T cells. Proc. Natl. Acad. Sci. USA. 87:1990;9353-9357.
20. Paliogianni F., Kincaid R.L., Boumpas D.T. Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin-2 gene transcription by counteracting calcineurin-dependent pathways. J. Exp. Med. 178(5):1993;1813-1817.
21. Plaut, M., Lichtenstein, L.M., 1978. Cellular and chemical basis of the allergic inflammation response: component parts and control mechanisms. In: Middleton, E., Reed, C.E., Ellis, E.F., Mosby, C.V. (Eds.), Allergy: Principles and Practice, St. Louis, pp. 115-138.
22. Poluektova L.Y., Khan M.M. Protein kinase A inhibitors reverse histamine-mediated regulation of IL-5 secretion. Immunopharmacology. 39(1):1998;9-19.
23. Qiu R., Melmon L., Khan M.M. Effects of histamine-trifluoromethyl-toluidide derivative (HTMT) on intracellular calcium in human lymphocytes. J. Pharm. Exp. Therapeutics. 253(3):1990;1245-1251.
24. Qiu R., Melmon L., Khan M.M. Cyclic AMP is not a direct regulator of calcium flux and hydrolysis of phosphoinositides in human lymphocytes. Immunopharmacology. 25(1):1993;37-49.
25. Rezai A.R., Salazar-Gonzalez J.F., Martinez-Maza O., Bramhall J.B., Afrasiabi R., Kermani-Arab V. Histamine blocks interleukin-2 (IL-2) gene expression and regulates IL-2 receptor expression. Immunopharm. Immunotoxic. 12(3):1990;345-362.
26. Roszkowski W., Plaut M., Lichtenstein L.M. Selective display of histamine receptors on lymphocytes. Science. 195:1977;683-685.
27. Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular cloning: a laboratory manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
28. Skalhegg B.S., Tasken K., Hansson V., Huitfeldt H.S., Jahnsen T., Lea T. Location of cAMPS-dependent protein kinase type I with the TCR-CD3 complex. Science. 263(5143):1994;84-87.
29. Skalhegg B.S., Rasmussen A.M., Tasken K., Hansson V., Jahnsen T., Lea T. Cyclic AMP sensitive signaling by the CD28 marker requires concomitant stimulation by the T-cell antigen receptor (TCR/CD3) complex. Scand. J. Immunol. 40(2):1994;201-208.
30. Snjidewint F.G.M., Kalinski P., Wierenga E.A., Bos J.D., Kapsenberg M.L. Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J. Immunol. 150(12):1993;5321-5329.
31. Sugiyama H., Chen P., Hunter M.G., Sitkovsky M.V. Perturbation of the expression of the catalytic subunit Cα of cyclic AMP-dependent protein kinase inhibits TCR-triggered secretion of IL-2 by T helper hybridoma cells. J. Immunol. 158(1):1997;171-179.
32. Van der Pouw-Kraan T., Van Kooten C., Rensink I., Aarden L. Interleukin (IL)-4 production by human T cells: differential regulation of IL-4 vs. IL-2 production. Eur. J. Immunol. 22(5):1992;1237-1241.