-
1
-
-
0023192180
-
The active form of tumor necrosis factor is a trimer
-
Smith RA, Baglioni C (1987) The active form of tumor necrosis factor is a trimer. J Biol Chem 262:6951-6954.
-
(1987)
J Biol Chem
, vol.262
, pp. 6951-6954
-
-
Smith, R.A.1
Baglioni, C.2
-
2
-
-
0024281428
-
A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF
-
Kriegler M, Perez C, DeFay K, Albert I, Lu SD (1988) A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF. Cell 53:45-53.
-
(1988)
Cell
, vol.53
, pp. 45-53
-
-
Kriegler, M.1
Perez, C.2
DeFay, K.3
Albert, I.4
Lu, S.D.5
-
3
-
-
0028277663
-
Unraveling function in the TNF ligand and receptor families
-
Beutler B, van Huffel C (1994) Unraveling function in the TNF ligand and receptor families. Science 264:667-668.
-
(1994)
Science
, vol.264
, pp. 667-668
-
-
Beutler, B.1
Van Huffel, C.2
-
6
-
-
0025884625
-
Tumor necrosis factor characterization at the molecular, cellular and in vivo level
-
Fiers W (1991) Tumor necrosis factor characterization at the molecular, cellular and in vivo level. FEBS Lett 285:199-212.
-
(1991)
FEBS Lett
, vol.285
, pp. 199-212
-
-
Fiers, W.1
-
7
-
-
0023105107
-
HLA class II induction in human islet cells by interferon-γ plus tumor necrosis factor or lymphotoxin
-
Pujol-Borrel R, Todd I, Doshi M, Bottazzo GF, Sutton R, Gray D, Adolf GR, Feldmann M (1987) HLA class II induction in human islet cells by interferon-γ plus tumor necrosis factor or lymphotoxin. Nature 326:304-306.
-
(1987)
Nature
, vol.326
, pp. 304-306
-
-
Pujol-Borrel, R.1
Todd, I.2
Doshi, M.3
Bottazzo, G.F.4
Sutton, R.5
Gray, D.6
Adolf, G.R.7
Feldmann, M.8
-
8
-
-
0023693142
-
The role of tumor necrosis factor (cachectin) in cachexia
-
Oliff A (1988) The role of tumor necrosis factor (cachectin) in cachexia. Cell 54:141-142.
-
(1988)
Cell
, vol.54
, pp. 141-142
-
-
Oliff, A.1
-
9
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
-
Tracey KJ, Fong Y, Hesse DG, Manogue KR, Lee AT, Kuo GC, Lowry SF, Cerami A (1987) Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330:662-664.
-
(1987)
Nature
, vol.330
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
Manogue, K.R.4
Lee, A.T.5
Kuo, G.C.6
Lowry, S.F.7
Cerami, A.8
-
10
-
-
0025333163
-
Prophylactic and therapeutic effects of a monoclonal antibody to tumor necrosis factor-α in experimental gram-negative shock
-
Silva AT, Bayston KF, Cohen J (1990) Prophylactic and therapeutic effects of a monoclonal antibody to tumor necrosis factor-α in experimental gram-negative shock. J Infect Dis 162:421-427.
-
(1990)
J Infect Dis
, vol.162
, pp. 421-427
-
-
Silva, A.T.1
Bayston, K.F.2
Cohen, J.3
-
11
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
Williams RO, Feldmann M, Maini RN (1992) Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Nat Acad Sci USA 89:9784-9788.
-
(1992)
Proc Nat Acad Sci USA
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
-
12
-
-
0028143211
-
Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor α (cA2) versus placebo in rheumatoid arthritis
-
Elliott MJ, Maini RN, Feldmann M, Kalden JR, Antoni C, Smolen JS, Leeb B, Breedveld FC, Macfarlane JD, Bijl H, Woody JN (1994) Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor α (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105-1110.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Kalden, J.R.4
Antoni, C.5
Smolen, J.S.6
Leeb, B.7
Breedveld, F.C.8
Macfarlane, J.D.9
Bijl, H.10
Woody, J.N.11
-
13
-
-
0030954732
-
A double-blind, placebo-controlled, dose-ranging study of anti-tumor necrosis factor-alpha chimeric monoclonal antibody (cA2) in the treatment of Crohn's disease
-
Targan SR, Hanauer SB, Van Deventer SJH, Mayer L, Present DH, Braakman TAJ, DeWoody KL, Schaible TF, Rutgeerts P (1997) A double-blind, placebo-controlled, dose-ranging study of anti-tumor necrosis factor-alpha chimeric monoclonal antibody (cA2) in the treatment of Crohn's disease. N Engl J Med 337:1025-1035.
-
(1997)
N Engl J Med
, vol.337
, pp. 1025-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.H.3
Mayer, L.4
Present, D.H.5
Braakman, T.A.J.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.9
-
14
-
-
0026419319
-
Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery
-
Houghten RA, Pinilla C, Blondelle SE, Appel JR, Dooley CT, Cuervo JH (1991) Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature 354:84-86.
-
(1991)
Nature
, vol.354
, pp. 84-86
-
-
Houghten, R.A.1
Pinilla, C.2
Blondelle, S.E.3
Appel, J.R.4
Dooley, C.T.5
Cuervo, J.H.6
-
16
-
-
0026419328
-
A new type of synthetic peptide library for identifying ligand-binding activity
-
Lam KS, Salmon SE, Hersh EM, Hruby VJ, Kazmierski WM, Knapp J (1991) A new type of synthetic peptide library for identifying ligand-binding activity. Nature 354:82-84.
-
(1991)
Nature
, vol.354
, pp. 82-84
-
-
Lam, K.S.1
Salmon, S.E.2
Hersh, E.M.3
Hruby, V.J.4
Kazmierski, W.M.5
Knapp, J.6
-
17
-
-
0013597276
-
Identification of related peptides recognized by a monoclonal antibody using a synthetic peptide combinatorial library
-
Appel JR, Pinilla C, Houghten RA (1992) Identification of related peptides recognized by a monoclonal antibody using a synthetic peptide combinatorial library. Immunol Methods 1:17-23.
-
(1992)
Immunol Methods
, vol.1
, pp. 17-23
-
-
Appel, J.R.1
Pinilla, C.2
Houghten, R.A.3
-
18
-
-
0013570873
-
Determination of multiple binding specificities of a monoclonal antibody using a synthetic peptide combinatorial library
-
In Schneider CJ, Eberle AN (eds), Leiden
-
Pinilla C, Appel JR, Chendra S, Houghten RA (1993) Determination of multiple binding specificities of a monoclonal antibody using a synthetic peptide combinatorial library. In Schneider CJ, Eberle AN (eds) Peptides: Proceedings of the 22nd European Peptide Symposium, Leiden, pp. 903-904.
-
(1993)
Peptides: Proceedings of the 22nd European Peptide Symposium
, pp. 903-904
-
-
Pinilla, C.1
Appel, J.R.2
Chendra, S.3
Houghten, R.A.4
-
19
-
-
0027276388
-
Synthetic peptide combinatorial libraries (SPCLs): Identification of the antigenic determinant of β-endorphin recognized by monoclonal antibody 3E7
-
Pinilla C, Appel JR, Houghten RA (1993) Synthetic peptide combinatorial libraries (SPCLs): Identification of the antigenic determinant of β-endorphin recognized by monoclonal antibody 3E7. Gene 128:71-76.
-
(1993)
Gene
, vol.128
, pp. 71-76
-
-
Pinilla, C.1
Appel, J.R.2
Houghten, R.A.3
-
20
-
-
0027450097
-
The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid ligands
-
Dooley CT, Houghten RA (1993) The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid ligands. Life Sci 52:1509-1517.
-
(1993)
Life Sci
, vol.52
, pp. 1509-1517
-
-
Dooley, C.T.1
Houghten, R.A.2
-
21
-
-
0002966546
-
Development of new antimicrobial agents using synthetic peptide combinatorial library involving more than 34 million hexamers
-
In Epton R (ed.). Oxford, Solid Phase Conference Coordination
-
Houghten RA, Blondelle SE, Cuervo JH (1992) Development of new antimicrobial agents using synthetic peptide combinatorial library involving more than 34 million hexamers. In Epton R (ed.) Innovation and Perspectives in Solid Phase Peptide Synthesis: Peptides, Polypeptides and Oligonucleotides. Oxford, Solid Phase Conference Coordination, pp. 237-239.
-
(1992)
Innovation and Perspectives in Solid Phase Peptide Synthesis: Peptides, Polypeptides and Oligonucleotides
, pp. 237-239
-
-
Houghten, R.A.1
Blondelle, S.E.2
Cuervo, J.H.3
-
22
-
-
0013596553
-
The systematic development of peptides having potent antimicrobial activity against E. coli through the use of synthetic peptide combinatorial libraries
-
In Angeletti RH (ed.). Orlando, Academic Press
-
Houghten RA, Dinh KT, Burcin DE, Blondelle SE (1993) The systematic development of peptides having potent antimicrobial activity against E. coli through the use of synthetic peptide combinatorial libraries. In Angeletti RH (ed.) Techniques in Protein Chemistry IV. Orlando, Academic Press, pp 249-256.
-
(1993)
Techniques in Protein Chemistry
, vol.4
, pp. 249-256
-
-
Houghten, R.A.1
Dinh, K.T.2
Burcin, D.E.3
Blondelle, S.E.4
-
23
-
-
0028577207
-
An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library
-
Dooley CT, Chung NN, Wilkes BC, Schiller PW, Midlack JM, Pasternak GW, Houghten RA (1994) An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library. Science 266:2019-2022.
-
(1994)
Science
, vol.266
, pp. 2019-2022
-
-
Dooley, C.T.1
Chung, N.N.2
Wilkes, B.C.3
Schiller, P.W.4
Midlack, J.M.5
Pasternak, G.W.6
Houghten, R.A.7
-
24
-
-
0027722211
-
Discovery of D-amino-acid-containing ligands with selectide technology
-
Lam KS, Lebl M, Krchnak V, Wade S, Abdul-Latif F, Ferguson R, Cuzzocrea C, Wertman K (1993) Discovery of D-amino-acid-containing ligands with selectide technology. Gene 137:13-16.
-
(1993)
Gene
, vol.137
, pp. 13-16
-
-
Lam, K.S.1
Lebl, M.2
Krchnak, V.3
Wade, S.4
Abdul-Latif, F.5
Ferguson, R.6
Cuzzocrea, C.7
Wertman, K.8
-
25
-
-
0025964038
-
Structure, function and properties of antibody binding sites
-
Mian S, Bradwell AR, Olson AJ (1991) Structure, function and properties of antibody binding sites. J Mol Biol 217:133-151.
-
(1991)
J Mol Biol
, vol.217
, pp. 133-151
-
-
Mian, S.1
Bradwell, A.R.2
Olson, A.J.3
-
26
-
-
0028810703
-
Functional comparisons of different tumor necrosis factor receptor/IgG fusion proteins
-
Scallon BJ, Trinh H, Nedelman M, Brennan FM, Feldmann M, Ghrayeb J (1995) Functional comparisons of different tumor necrosis factor receptor/IgG fusion proteins. Cytokine 7:759-770.
-
(1995)
Cytokine
, vol.7
, pp. 759-770
-
-
Scallon, B.J.1
Trinh, H.2
Nedelman, M.3
Brennan, F.M.4
Feldmann, M.5
Ghrayeb, J.6
-
27
-
-
0027361432
-
Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
-
Knight DM, Trinh H, Le J, Siegel S, Shealy D, McDonough M, Scallon B, Moore MA, Vilcek J, Daddona P, Ghrayeb J (1993) Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol 30:1443-1453.
-
(1993)
Mol Immunol
, vol.30
, pp. 1443-1453
-
-
Knight, D.M.1
Trinh, H.2
Le, J.3
Siegel, S.4
Shealy, D.5
McDonough, M.6
Scallon, B.7
Moore, M.A.8
Vilcek, J.9
Daddona, P.10
Ghrayeb, J.11
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