Morphometric studies of secretory granule formation in mouse pancreatic acinar cells. Dissecting the early structural changes following pilocarpine injection

Journal of Anatomy

Volumn 194, Issue 1, 1999, Pages 51-60

  Hammel, Ilan ^a   Shor Hazan, Osnat ^a   Eldar, Tora ^a   Amihai, Dina ^a   Lew, Sylvia ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b MEIR MEDICAL CENTER   (Israel)

Author keywords

Autophagosomes; Endoplasmic reticulum; Mitochondria; Zymogen granule synthesis

Indexed keywords

PILOCARPINE; ZYMOGEN GRANULE;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL NUCLEUS; CELL ULTRASTRUCTURE; CELL VACUOLE; DEGRANULATION; ELECTRON MICROSCOPY; FEMALE; GOLGI COMPLEX; MITOCHONDRION; MOUSE; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; ROUGH ENDOPLASMIC RETICULUM; SECRETORY GRANULE; TIME;

ANIMALS; CELL DEGRANULATION; CELL MEMBRANE; CYTOPLASMIC GRANULES; ENDOPLASMIC RETICULUM, ROUGH; FEMALE; MICE; MICE, INBRED ICR; MICROSCOPY, ELECTRON; MITOCHONDRIA; PANCREAS; PILOCARPINE; STIMULATION, CHEMICAL;

ANIMALIA;

EID: 0033054354     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0021878298004324     Document Type: Article

References (36)

1. AUGHTEEN AA, COPE GH (1987) Changes in the size and number of secretion granules in the rat exocrine pancreas induced by feeding or stimulation in vitro. A morphometric study. Cell and Tissue Research 249, 427-436.
2. CASTLE JD, CAMERON RS, ARYAN P, VON ZASTROW M, RUDNICK G (1987) Similarities and differences among neuroendocrine, exocrine and endocytic vesicles. Annals of New York Academy of Sciences 493, 448-460.
3. COPE GH (1983) Exocrine glands and protein secretion: a stereological viewpoint. Journal of Microscopy 131, 187-202.
4. COVELL WP (1928) A microscopic study of pancreatic secretion in the living animal. Anatomical Record 40, 213-224.
5. DARNELL J, LODISH H, BALTIMORE D (1990) Plasma-membrane, secretory and lysosome proteins: biosynthesis and sorting. In Molecular Cell Biology, 2nd edn, pp. 639-680. New York: Scientific American Books.
6. DUNN Jr WA (1990) Studies on the mechanism of autophagy : formation of the autophagic vacuole. Journal of Cell Biology 110, 1923-1933.
7. FARQUHAR MG (1985) Progress in unraveling pathways of Golgi traffic. Annual Review of Cell Biology 1, 447-488.
8. FARQUHAR MG, PALADE GE (1981). The Golgi apparatus (complex) (1954-1981) - from artifact to center stage. Journal of Cell Biology 91, 77s-103s.
9. GEUZE JJ, KRAMER MF (1974). Function of coated membranes and multivesicular bodies during membrane regulation in stimulated exocrine pancreas cells. Cell and Tissue Research 156, 1-20.
10. GUNDERSEN HJG, JENSEN EB (1985) Stereological estimation of the volume-weighted mean volume of arbitary particles observed on random sections. Journal of Microscopy 138, 127-142.
11. HAMMEL I, DVORAK AM, PETERS SP, SCHULMAN ES, DVORAK HF, LICHTENSTEIN LM et al. (1985) Differences in the volume distributions of human lung mast cell granules and lipid bodies : evidence that the size of these organelles is regulated by distinct mechanisms. Journal of Cell Biology 100, 1488-1492.
12. 3H]-glycine administration in vivo. Cell and Tissue Research 293, 445-452.
13. HAMMEL I, DVORAK AM, GALLI SJ (1987). Defective cytoplasmic granule formation. I. Abnormalities affecting tissue mast cells and pancreatic acinar cells of beige mice. Laboratory Investigation 56, 321-328.
14. HAMMEL I, LAGUNOFF D, KRÜGER P-G (1989). Recovery of rat mast cells after secretion: a morphometric study. Experimental Cell Research 184, 518-523.
15. JENA BP, GUMKOWSKI FD, KONIECZKO EM, VON MOLLARD GF, JAHN R, JAMIESON JD (1994) Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells during regulated exocytosis. Journal of Cell Biology 124, 43-53.
16. JENSEN EB, GUNDERSEN HJG (1985) The stereological estimation of moments of particle volume. Journal of Applied Probability 22, 82-98.
17. JAMIESON JD, PALADE GE (1967) Intracellular transport of secretory proteins in the pancreatic exocrine cell. II. Transport to condensing vacuoles and zymogen granules. Journal of Cell Biology 34, 597-615.
18. JAMIESON JD, PALADE GE (1971) Condensing vacuole conversion and zymogen granule discharge in pancreatic exocrine cells : metabolic studies. Journal of Cell Biology 48, 503-522.
19. KALINA M, ROBINOVITCH R (1975) Exocytosis couples to endocytosis of ferritin in parotid acinar cells from isoprenalin stimulated rats. Cell and Tissue Research 163, 373-382.
20. LEBLOND CP (1981) The life history of cells in renewing systems. American Journal of Anatomy 160, 114-158.
21. LEW S, HAMMEL I, GALLI SJ (1994) Cytoplasmic granule formation in mouse pancreatic acinar cells. I. Quantitative recognisis of changes in the size distribution of progranules and mature granules after pilocarpine-induced secretion. Cell and Tissue Research 278, 327-336.
22. NEVALAINEN TJ (1970) Effects of pilocarpine stimulation on rat pancreatic acinar cells. Acta Pathologica et Microbiologica Immunologica Scandinavica (Supplementum) 210, 1-70.
23. OKANO Y, NAKAMURA T (1965) Electron microscopic observations on exocrine pancreas cells in mice following the injection of pilocarpine. Journal of Electron Microscopy (Tokyo) 14, 242-243.
24. OLIVER C (1982) Endocytic pathways at the lateral and basal cell surfaces of exocrine acinar cells. Journal of Cell Biology 95, 154-161.
25. PFEFFER SR, ROTHMAN JE (1987) Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annual Review of Biochemistry 56, 829-859.
26. REZ G, CSAK J, FELLINGER E, LASZLO L, KOVACS AL, OLIVA O et al. (1996) Time course of vinblastine-induced autophagocytosis and changes in the endoplasmic reticulum in murine pancreatic acinar cells : a morphometric and biochemical study. European Journal of Cell Biology 71, 341-350.
27. SCHROEDER F, JEFFERSON JR, KIER AB, KNITTEL J, SCALLEN TJ, WOOD WG et al. (1991) Membrane cholesterol dynamics : cholesterol domains and kinetic pools. Proceeding of the Society of Experimental Biology and Medicine 196, 235-252.
28. SEVERS NJ, ROBENEK H (1983) Detection of microdomains in biomembranes. An appraisal of recent developments in freeze-fracture cytochemistry. Biochimica et Biophysica Acta 737, 373-408.
29. UCHIYAMA Y, SAITO K (1982). A morphometric study of 24-hour variations in subcellular structures of the rat pancreatic acinar cell. Cell and Tissue Research 226, 609-620.
30. UNDERWOOD EE (1970) Quantitative Stereology. Reading, MA: Addison-Wesley.
31. WATARI N, BABA N (1968). Several findings on the fine structural alterations of the exocrine pancreas after the administration of some chemicals. Journal of Electron Microscopy (Tokyo) 17, 327-341.
32. WEIBEL ER (1979) Stereological Methods, vol 1. Practical Methods for Biological Morphometry, and vol 2. Theoretical Foundations. London: Academic Press.
33. WEIBEL ER (1979) Stereological Methods, vol 1. Practical Methods for Biological Morphometry, and vol 2. Theoretical Foundations. London: Academic Press.
34. WEINTRAUB H, ABRAMOVICI A, AMICHAI D, ELDAR T, BEN-DOR L, PENTCHEV PG et al. (1992) Morphometric studies of pancreatic acinar granule formation in NCTR-Balb/c mice. Journal of Cell Science 102, 141-147.
35. WILLIAMS MA (1977) Stereological techniques. In Quantitative Methods in Biology, pp. 5-84. New York : North-Holland.
36. WILLIAMS MA, Cope GH (1981) Membrane dynamics in the parotid acinar cell during regranulation: a stereological study following isoprenaline-induced secretion. Anatomical Record 199, 389-401.