4-Chloro-m-cresol is a trigger of malignant hyperthermia in susceptible swine

Anesthesiology

Volumn 90, Issue 6, 1999, Pages 1733-1740

  Wappler, Frank ^a   Scholz, Jens ^b   Fiege, Marko ^b   Kolodzie, Kerstin ^b   Kudlik, Christiana ^b   Weißhorn, Ralf ^b   Schulte Am Esch, Jochen ^b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b NONE

Author keywords

Caffeine; Dantrolene; Halothane; In vitro contracture test

Indexed keywords

CAFFEINE; CHLOROCRESOL; DANTROLENE; HALOTHANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; DRUG EFFECT; HYPERMETABOLISM; LACTATE BLOOD LEVEL; MALIGNANT HYPERTHERMIA; MUSCLE CONTRACTURE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SKELETAL MUSCLE; SWINE; TISSUE DISTRIBUTION;

ANIMALS; CALCIUM; CRESOLS; HEART RATE; MALIGNANT HYPERTHERMIA; MUSCLE CONTRACTION; PRESERVATIVES, PHARMACEUTICAL; SWINE;

EID: 0033053775     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199906000-00031     Document Type: Article

References (30)

1. Gronert GA, Antognini JF: Malignant hyperthermia, Anesthesia, 4th edition. Edited by Miller RD. New York, Churchill Livingstone, 1994, pp 1075-93
2. MacLennan DH, Phillips MS: Malignant hyperthermia. Science 1992; 256:789-94
3. Mickelson JR, Gallant EM, Litterer LA, Johnson KM, Rempel WE, Louis CF: Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia. J Biol Chem 1988; 263:9310-5
4. Fill M, Coronado R, Mickelson JR, Vilven J, Ma J, Jacobson BA, Louis CF: Abnormal ryanodine receptor channels in malignant hyperthermia. Biophys J 1990; 50:471-5
5. Pessah IN, Lynch C, Gronert GA: Complex pharmacology of malignant hyperthermia. ANESTHESIOLOGY 1996; 84:1275-9
6. Foster PS, Gesini E, Claudianos C, Hopkinson KC, Denborough MA: Inositol 1,4,5-trisphosphate phosphatase deficiency and malignant hyperpyrexia in swine. Lancet 1989; 2:124-7
7. Scholz J, Troll U, Schulte am Esch J, Hartung E, Patten M, Sandig P, Schmitz W: Inositol-1,4,5-trisphosphate and malignant hyperthermia. Lancet 1991; 337:1361
8. Wappler F, Scholz J, Köchling A, Steinfath M, Krause T, Schulte am Esch J: Inositol-1,4,5-trisphosphate in blood and skeletal muscle in human malignant hyperthermia. Br J Anaesth 1997, 78:541-7
9. Coronado R, Morrissette J, Sukhareva M, Vaughan DM: Structure and function of ryanodine receptors. Am J Physiol 1994; 266:C1485-504
10. Galloway GJ, Denborough MA: Suxamethonium chloride and malignant hyperpyrexia. Br J Anaesth 1986; 58:447-50
11. 2+ channel. ANESTHESIOLOGY 1996; 84:1380-5
12. Wappler F, Scholz J, von Richthofen V, Fiege M, Steinfath M, Schulte am Esch J: 4-Chloro-m-Cresol induziert Kontrakturen an Skelettmuskelpräparaten von Patienten mit Disposition zu maligner Hyperthermie. Anästhesiol Intensivmed Notfallmed Schmerzther 1997; 32:541-8
13. 2+ release. Mol Pharmacol 1993; 44:1192-201
14. Herrmann-Frank A, Richter M, Sarközi S, Mohr U, Lehmann-Horn F: 4-Chloro-m-cresol, a potent and specific activator of the skeletal muscle ryanodine receptor. Biophys Biochim Acta 1996; 1289:31-40
15. Herrmann-Frank A, Richter M, Lehmann-Horn F: 4-Chloro-m-Cresol: A specific tool to distinguish between malignant hyperthermia-susceptible and normal muscle. Biochem Pharmacol 1996; 52:149-55
16. Ørding H, Brancadoro V, Cozzolino S, Ellis FR, Glauber V, Gonano EF, Halsall PJ, Hartung E, Heffron JJA, Heytens L, Kozak-Ribbens G, Kress H, Krivosic-Horber R, Lehmann-Horn F, Mortier W, Nivoche Y, Ranklev-Twetman E, Sigurdson S, Snoeck M, Stieglitz P, Tegazzin V, Urwyler A, Wappler F: In vitro contracture test for diagnosis of malignant hyperthermia following the protocol of the European MH Group: Results of testing patients surviving fulminant MH and un-related low-risk subjects. Acta Anaesthesiol Scand 1997; 41:955-66
17. Wappler F, Roewer N, Köchling A, Braune H, Reissinger T, Schulte am Esch J: Fulminant malignant hyperthermia associated with ketoacidotic diabetic coma. Intensive Care Med 1996; 22:809-12
18. Wedel DJ, Gammel SA, Milde JH, Iaizzo PA: Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine. ANESTHESIOLOGY 1993; 78: 1138-44
19. Iaizzo PA, Wedel DJ: Response to succinylcholine in porcine malignant hyperthermia. Anesth Analg 1994; 79:143-51
20. Forrest T, Ramage DTO: Cardiac dysrhythmia after subtrigonal phenol. Anaesthesia 1987; 42:777-8
21. Fujii J, Otsu K, Zorzato F, De Leon S, Khanna K, Weiler JE, O'Brien PJ, MacLennan DH: Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 1991; 253:448-51
22. MacLennan DH, Duff C, Zorzato F, Fujii J, Phillips M, Korneluk RG, Frodis W, Britt BA, Worton RG: Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia. Nature 1990; 343:559-61
23. McCarthy TV, Healy JMS, Heffron JJA, Lehane M, Deufel T, Lehmann-Horn F, Farrall M, Johnson K: Localisation of the malignant hyperthermia susceptibility locus to human chromosome 19q 12-13.2. Nature 1990; 343:562-4
24. Ball SP, Johnson KJ: The genetics of malignant hyperthermia. J Med Genet 1993; 30:89-93
25. Deufel T, Sudbrak R, Feist Y, Rübsam B, Du Chesne I, Schafer KL, Roewer N, Grimm T, Lehmann-Horn F, Hartung EJ, Müller CR: Discordance, in a malignant hyperthermia pedigree, between in vitro contracture-test phenotypes and haplotypes for the MHSI region on chromosome 19q12-13.2, comprising the C1840T transition in the RYRI gene. Am J Hum Genet 1995; 56:1334-42
26. 2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hypothermia and/or central core disease. J Biol Chem 1997; 272:26332-9
27. Urwyler A, Censier K, Kaufmann M, Drewe J: Genetic effects on the variability of the halothane and caffeine muscle contracture tests. ANESTHESIOLOGY 1994; 80:1287-95
28. Halsall PJ, Caine PA, Ellis FR: Retrospective analysis of anaesthetics received by patients before susceptibility to malignant hyperpyrexia was recognized. Br J Anaesth 1979; 51:949-54
29. Iaizzo PA, Kehler CH, Carr RJ, Sessler DI, Belani KG: Prior hypothermia attenuates malignant hyperthermia in susceptible swine. Anesth Analg 1996; 82:796-802
30. + channels by phenol, p-cresol, and benzyl alcohol. Mol Pharmacol 1997; 51:475-83