Expression of five novel T-box genes and brachyury during embryogenesis, and in developing and regenerating limbs and tails of newts

Development Growth and Differentiation

Volumn 41, Issue 3, 1999, Pages 321-333

  Sone, Kiyoaki ^a   Takahashi, Tadashi C ^b   Takabatake, Yuka ^a   Takeshima, Kazuhito ^a   Takabatake, Takashi ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b Biohistory Research Hall ^*  (Japan)

Author keywords

Limb; Newt; Regeneration; T box genes; Tail

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; LIMB DEVELOPMENT; LIMB REGENERATION; NEWT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; TAIL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA PRIMERS; DNA-BINDING PROTEINS; EXTREMITIES; FETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MOLECULAR SEQUENCE DATA; REGENERATION; SALAMANDRIDAE; SEQUENCE HOMOLOGY, AMINO ACID; T-BOX DOMAIN PROTEINS; TAIL; TRANSCRIPTION FACTORS;

ANIMALIA; MAMMALIA; SALAMANDRIDAE; VERTEBRATA;

EID: 0033053042     PISSN: 00121592     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-169X.1999.413435.x     Document Type: Article

References (50)

1. Agulnik, S. I., Garvey, N., Hancock, S. et al. 1996. Evolution of mouse T-box genes by tandem duplication and cluster dispersion. Genetics 144, 249-254.
2. Bamshad, M., Lin, R. C., Law, D. J. et al. 1997. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nature Genet. 16, 311-315.
3. Basson, C. T., Bachinsky, D. R., Lin, R. C. et al. 1997. Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome. Nature Genet. 15, 30-35.
4. Bollag, R. J., Siegfried, Z., Cebra-Thomas, J. A., Garvey, N., Davison, E. M. & Silver, L. M. 1994. An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus. Nature Genet. 7, 383-389.
5. Casey, E. S., O'Reilly, M-A. J., Conlon, F. L. & Smith, J. C. 1998. The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element. Development 125, 3887-3894.
6. Cohn, M. J., Izpisüa-Belmonte, J. C., Abud, H., Heath, J. K. & Tickle, C. 1995. Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.
7. Crossley, P. H., Minowada, G., MacArthur, C. A. & Martin, G. R. 1996. Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.
8. Cvekl, A. & Piatigorsky, J. 1996. Lens development and crystallin gene expression: Many rotes for Pax-6. Bioessay 18, 621-630.
9. Del Rio-Tsonis, K., Jung, J. C., Chiu, I. M. & Tsonis, P. A. 1997. Conservation of fibroblast growth factor function in lens regeneration. Proc. Natl Acad. Sci. USA 94, 13701-13706.
10. Dent, J. M. 1962. Limb regeneration in larvae and metamorphosing individuals of the South African clawed toad. J. Morphol. 110, 61-77.
11. Endo, T., Yokoyama, H., Tamura, K. & Ide, H. 1997. Shh expression in developing and regenerating limb buds of Xenopus laevis. Dev. Dyn. 209, 227-232.
12. Filoni, S., Bernardini, S., Cannata, S. M. & D'Alessio, A. 1997. Lens regeneration in larval Xenopus laevis: Experimental analysis of the decline in the regenerative capacity during development. Dev. Biol. 187, 13-24.
13. Gardiner, D. M., Blumberg, B., Komine, Y. & Bryant, S. 1995. Regulation of HoxA expression in developing and regenerating axolotl limbs. Development 121, 1731-1741.
14. Gibson-Brown, J. J., Agulnik, S. I., Chapman, D. L. et al. 1996. Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity. Mech. Dev. 56, 93-101.
15. Gibson-Brown, J. J., Agulnik, S. I., Silver, L. M. & Papaioannou, V. E. 1998a. Expression of T-box genes Tbx2-Tbx5 during chick organogenesis. Mech. Dev. 74, 165-169.
16. Gibson-Brown, J. J., Agulnik, S. I., Silver, L. M., Niswander, L. & Papaioannou, V. E. 1998b. Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development. Development 125, 2499-2509.
17. Grimm, S. & Pflugfelder, G. O. 1996. Control of the gene optomoter-blind in Drosophila wing development by decapentaplegic and wingless. Science 271, 1601-1604.
18. Harland, R. M. 1991. In situ hybridization: An improved whole-mount method for Xenopus embryos. In Methods in Cell Biology, Vol. 36, (Ed. B. K. Kay & H. B. Peng), pp. 685-695. Academic Press, San Diego.
19. Isaac, A., Rodriguez-Esteban, C., Ryan, A. et al. 1998. Tbx genes and limb identity in chick embryo development. Development 125, 1867-1875.
20. Isaacs, H. V., Tannahill, D. & Slack, J. M. W. 1992. Expression of a novel FGF in the Xenopus embryo: A new candidate inducing factor for mesoderm formation and anteroposterior specification. Development 114, 711-720.
21. Iten, L. E. & Bryant, S. V. 1973. Forelimb regeneration from different levels of amputation in the newt, Notophthalmus viridescens: Length, rate, and stages. Wilhelm Roux' Archiv. 173, 262-282.
22. Iten, L. E. & Bryant, S. V. 1976. Stages of tail regeneration in the adult newt, Notophthalmus viridescens. J. Exp. Zool. 196, 283-292.
23. Logan, M., Simon, H-G. & Tabin, C. 1998. Differential regulation of T-box and homeobox transcription factors suggests roles in controlling chick limb-type identity. Development 125, 2825-2835.
24. McDevitt, D. S., Brahma, S. K., Courtois, Y. & Jeanny, J. C. 1997. Fibroblast growth factor receptors and regeneration of the eye lens. Dev. Dyn. 208, 220-226.
25. Ogawa, M., Takahashi, T. C., Takabatake, T. & Takeshima, K. 1998. Isolation and characterization of a gene expressed mainly in the gastric epithelium, a novel member of the ep37 family that belongs to the βγ-crystallin superfamily. Develop. Growth Differ. 40, 465-473.
26. Ohuchi, H., Nakagawa, T., Yamamoto, A. et al. 1997. The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor. Development 124, 2235-2244.
27. Ohuchi, H., Nakagawa, T., Yamauchi, M. et al. 1995. An additional limb can be induced from the flank of the chick embryo by FGF4. Biochem. Biophys. Res. Commun. 209, 809-816.
28. Ohuchi, H., Takeuchi, J., Yoshioka, H. et al. 1998. Correlation of wing-leg identity in ectopic FGF-induced chimeric limbs with the deferential expression of chick Tbx5 and Tbx4. Development 125, 51-60.
29. Okada, Y. K. & Ichikawa, M. 1947. Normal table of Trituras pyrrhogaster. Appl. J. Exp. Morphol. 3, 1-16.
30. Papaioannou, V. E. & Silver, L. M. 1998. The T-box gene family. Bioessays 20, 9-19.
31. Park, C. M. & Hollenberg, M. J. 1991. Induction of retinal regeneration in vivo by growth factors. Dev. Biol. 148, 322-333.
32. Poulin, M. L. & Chiu, I. M. 1995. Re-programming of expression of the FGFR and bek variants of fibroblast growth factor receptor 2 during limb regeneration in newts (Notophthalmus viridescens). Dev. Dyn. 202, 378-387.
33. Poulin, M. L., Patrie, K. M., Botelho, M. J., Tassava, R. A. & Chiu, I. M. 1993. Heterogeneity in the expression of fibroblast growth factor receptors during limb regeneration in newts (Notophthalmus viridescens). Development 119, 353-361.
34. Pflugfelder, G. O., Roth, H. & Poeck, B. 1992. A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding. Biochem. Biophys. Res. Commun. 186, 918-925.
35. Ryan, K., Garrett, N., Mitchell, A. & Gurdon, J. B. 1996. Eomesodermin, a key early gene in Xenopus mesoderm differentiation. Cell 87, 989-1000.
36. Savard, P., Gates, P. B. & Brocks, J. P. 1988. Position dependent expression of a homeobox gene transcript in relation to amphibian limb regeneration. EMBO J. 7, 4275-4282.
37. Simon, H-G., Kittappa, R., Khan, P. A., Tsilfidis, C., Liversage, R. A. & Oppenheimer, S. 1997. A novel family of T-box genes in urodele amphibian limb development and regeneration: Candidate genes involved in vertebrate forelimb/hindlimb patterning. Development 124, 1355-1366.
38. Simon, H-G. & Tabin, C. J. 1993. Analysis of Hox-4.5 and Hox-3.6 express of during newt limb regeneration: Differential regulation of paralogous Hox genes suggests different roles for members of different Hox clusters. Development 117, 1397-1407.
39. Smith, J. 1997. Brachyury and the T-box genes. Curr. Opin. Genet. Dev. 7, 474-480.
40. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. & Herrmann, B. G. 1991. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
41. Sone, K., Takeshima, K., Takahashi, T. C. & Takabatake, T. 1997. Temporal alteration of dose-dependent response to activin in newt animal-cap explants. Dev. Genes. Evol. 207, 147-155.
42. Stone, L. S. 1967. An investigation recording all salamanders which can and cannot regenerate a lens from the dorsal iris. J. Exp. Zool. 164, 87-104.
43. Tabin, C. J. 1989. Isolation of potential vertebrate limb-identity genes. Development 105, 813-820.
44. Takabatake, T., Ogawa, M., Takahashi, T. C., Mizuno, M., Okamoto, M. & Takeshima, K. 1997. Hedgehog and patched gene expression in adult ocular tissues. FEBS Lett. 410, 485-489.
45. Takabatake, T., Takahashi, T. C., Inoue, K., Ogawa, M. & Takeshima, K. 1996. Activation of Cynops genes, Fork Head and Sonic Hedgehog, in animal cap explants. Biochem. Biophys. Res. Commun. 218, 395-401.
46. Taylor, G. P., Anderson, R., Reginelli, A. D. & Muneoka, K. 1994. FGF-2 induces regeneration of the chick limb bud. Dev. Biol. 163, 282-284.
47. Vogel, A., Rodriguez, C. & Izpisúa-Belmonte, J. 1996. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750.
48. Wattler, S., Russ, A., Evans, M. & Nehls, M. 1998. A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members of the T-box family. Genomics 48, 24-33.
49. Zenjari, C., Boilly, B., Hondermarck, H. & Boilly-Marer, Y. 1997. Nerve-blastema interactions induce fibroblast growth factor-1 release during limb regeneration in Pleurodeles waltl. Develop. Growth Differ. 39, 15-22.
50. Zhang, J. & King, M. L. 1996. Xenopus VegTRNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning. Development 122, 4119-4129.