Studies on the mode of action of peppermint oil Mentha x piperita L. in the guinea-pig ileum in vitro

Medical Science Research

Volumn 27, Issue 5, 1999, Pages 307-309

  Lis Balchin, M ^a   Hart, S ^b  

^a LONDON SOUTH BANK UNIVERSITY   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cyclic adenosine monophosphate; Essential oil; Ileum; Mentha x piperita; Peppermint oil; Spasmolytic activity

Indexed keywords

ADRENERGIC RECEPTOR; ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; GUANYLATE CYCLASE INHIBITOR; PEPPERMINT OIL; PHENTOLAMINE; PHOSPHODIESTERASE INHIBITOR; PROPRANOLOL; SPASMOLYTIC AGENT; TREQUINSIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GUINEA PIG; ILEUM; INTESTINE CONTRACTION; MALE; NONHUMAN;

ANIMALIA; CANIS FAMILIARIS; CAVIA PORCELLUS; MENTHA X PIPERITA; SUS SCROFA;

EID: 0033052960     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Somerville KW, Richmond CR, Bell GD. Delayed release Peppermint oil capsules (Colpermin) for the spastic colon syndrome - a pharmacokinetic study. Br J Clin Pharm 1984; 18:638-640.
2. Nash P, Gould SR, Bernardo DE. Peppermint oil does not relieve the pain oflrritable Bowel Syndrome. Br J Clin Pract 1986; 40:292-293.
3. Leicester RJ, Hunt RH. Peppermint oil to reduce colonie spasm during endoscopy. Lancet 1982; 2:989.
4. Haginiwa J, Harada M, Morishita I. Pharmacological studies on crude drugs. VII Properties of essential oil components of aromatics and their pharmacological effects on mouse intestine. Yakugaku Zasshi 1963; 83:624-626.
5. Reiter M, Brandt W. Relaxant effects on trachéal and ileal smooth muscles of the guinea-pig. Arzneim-Forsch/drug Res 1985; 35:408-414.
6. Lis-Balchin M, Hart S, Deans SO, et al. Comparison of the pharmacological and antimicrobial action of commercial plant essential oils. J Herbs Spices Med Plants 1996; 4:69-86.
7. Lis-Balchin M, Deans S, Hart S. A study of the variability of commercial Peppermint oils using antimocrobial and pharmacological parameters. Med Sei Res 1997; 25:151-152.
8. Martindale. The Extra Pharmacopoeia, 30th ed. The Pharmaceutical Press; 1993.
9. Price S, Price L. Aromatherapy for Healthcare Professionals. Edinburgh: Churchill Livingstone; 1995.
10. Kubota M, Ikemoto T, Komaki R, Inui M. Odor and emotion - effects of essential oils on contingent negative variation. Proc 12th Inl Congress Flavours, Fragrances and Essential Oils, Vienna, Austria; 4-8 October 1992. pp. 456-461.
11. Manley CH. Psychophysiological effect of odor. Crit Rev Food Sci Nutr 1993; 33:57-62.
12. Torii S, Fakuda H, Kanemoto H, et al. In: Toller S, Dodds GH, (editors): Perfumery: The Psychology and Biology of Fragrance: New York: Chapman & Hall; 1988.
13. Hills JM, Aaronson PI. The mechanism of action of Peppermint oil on gastrointestinal smooth muscle. Gastroenterol 1991; 101:55-65.
14. Banner KH, Marchini F, Buschi A, Moriggi E, Semeraro C, Page CP. The effect of selective phosphodiesterase inhibitors in comparison with other anti-asthma drugs on Allergen-induced eosinophilia in guinea-pig airways. Pulm Pharmacol 1995; 8:37-42.
15. Lis-Balchin M, Patel J, Hart S. Studies on the Mode of Action of Essential Oils of Scented-leaf Pelargonium (Geraniaceae). Phytolher Res 1995; 12:215-217.
16. Lis-Balchin M. Hart S. Studies on the Mode of Action of the Essential Oil of Lavender (Lavandula angustifolia P. Miller,). Phytother Res. in press.
17. Lis-Balchin M, Hart S. Correlation of the chemical profiles of essential oil mixes with their relaxant and stimulant properties in man and smooth muscle preparations in vitro. Proc 27th Int Symp Ess Oils. Vienna. Austria. 8-11 September 1997. Franz Ch, Mathe A, Buchbauer G, (editors) Allured Pub. Corp. Carol Stream III 1997. pp. 24-28.
18. Hills JM, Potts HJ, Carlin BA, Parsons ME.An examination of the contribution made by the constituents of peppermint oil (PO) to the relaxation of gastrointestinal muscle. Br J Pharmacol 1990; 101:600P.
19. Buchbauer G, Jirovetz L, Czejka M, et al. New results in Aromatherapy research. 24th Int Symp Essential Oils, Berlin 10-13 September 1993.
20. Lis-Balchin M, Hart S. Preliminary study of the effect of essential oils on skeletal and smooth muscle in vitro. J. Ethnopharmacol 1997; 58: 183-187.
21. Elizabetsky E, Marschner J, Souza DO. Effects of linalool on glutamatergic system in the rat cerebral cortex. Neurochem Res 1995; 20: 461-465.