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Volumn 22, Issue 2, 1999, Pages 103-113

THF-γ2-mediated reduction of pulmonary metastases and augmentation of immunocompetence in C57BL/6 mice bearing B16-melanoma

Author keywords

B16 F10.9 melanoma; BCNU chemotherapy; Lung metastases; THF 2 immunotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; HUMORAL THYMUS FACTOR;

EID: 0033052746     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/00002371-199903000-00002     Document Type: Article
Times cited : (9)

References (51)
  • 1
    • 0023301838 scopus 로고
    • The biology of eaneer metastasis and implications for therapy
    • Fidler IJ, Baleh CM. The biology of eaneer metastasis and implications for therapy. Citrr Proh Sura 1987;24:137-209.
    • (1987) Citrr Proh Sura , vol.24 , pp. 137-209
    • Fidler, I.J.1    Baleh, C.M.2
  • 2
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren L, O’Reilly MS, Folkman J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nature Med 1995;1:149-53.
    • (1995) Nature Med , vol.1 , pp. 149-153
    • Holmgren, L.1    O’Reilly, M.S.2    Folkman, J.3
  • 3
    • 0004097423 scopus 로고
    • Principles of cancer chemotherapy
    • Haskell CM, ed, Philadelphia: WB Saunders
    • Haskell CM. Principles of cancer chemotherapy. In: Haskell CM, ed. Cancer treatment. Philadelphia: WB Saunders. 1995:31-57.
    • (1995) Cancer treatment , pp. 31-57
    • Haskell, C.M.1
  • 4
    • 0029556372 scopus 로고
    • High dose versus standard dose chemotherapy for the treatment of breast cancer. A review of current concepts
    • Fields KK, Elfenbein GJ, Perkins JB, Moscinski LC. High dose versus standard dose chemotherapy for the treatment of breast cancer. A review of current concepts. Ann NY Acad Sci 1995:770: 288-304.
    • (1995) Ann NY Acad Sci , vol.770 , pp. 288-304
    • Fields, K.K.1    Elfenbein, G.J.2    Perkins, J.B.3    Moscinski, L.C.4
  • 5
    • 0027345633 scopus 로고
    • Immunosuppressive factors in human cancer
    • San Diego: Academic Press
    • Sulitzeanu D. Immunosuppressive factors in human cancer. In: Advances in cancer research. San Diego: Academic Press. 1993:60 247-67.
    • (1993) Advances in cancer research , vol.60 , pp. 247-267
    • Sulitzeanu, D.1
  • 6
    • 0002907998 scopus 로고
    • Principles of biologic therapy
    • Haskell CM. ed, Philadelphia: WB Saunders
    • Quan WDY, Mitchell MS. Principles of biologic therapy. In: Haskell CM. ed. Cancer treatment. Philadelphia: WB Saunders, 1995:57-69.
    • (1995) Cancer treatment , pp. 57-69
    • Quan, W.D.Y.1    Mitchell, M.S.2
  • 7
    • 0029837616 scopus 로고    scopus 로고
    • Cancer immunotherapy: Hopes and pitfalls. A review
    • Ben-Efraim S. Cancer immunotherapy: hopes and pitfalls. A review. Anticancer Res 1996; 16:3235-40.
    • (1996) Anticancer Res , vol.16 , pp. 3235-3240
    • Ben-Efraim, S.1
  • 8
    • 0023951156 scopus 로고
    • THF-γ2: Purification and amino acid sequence of an immunoregulatory peptide from calf thymus
    • Burstein Y, Buchner V, Pecht M, Trainin N. THF-γ2: purification and amino acid sequence of an immunoregulatory peptide from calf thymus. Biochemistry 1988;27:4066-71.
    • (1988) Biochemistry , vol.27 , pp. 4066-4071
    • Burstein, Y.1    Buchner, V.2    Pecht, M.3    Trainin, N.4
  • 9
    • 0016695101 scopus 로고
    • Isolation and partial chemical characterization of THF, a thymus hormone involved in immune maturation of lymphoid cells
    • Kook AI, Yakir Y, Trainin N. Isolation and partial chemical characterization of THF, a thymus hormone involved in immune maturation of lymphoid cells. Cell Immunol 1975;19:151-7.
    • (1975) Cell Immunol , vol.19 , pp. 151-157
    • Kook, A.I.1    Yakir, Y.2    Trainin, N.3
  • 10
    • 0023628169 scopus 로고
    • Restoration of immunological responses by THF. a thymic hormone, in mice infected with murine cytomegalovirus (MCMV)
    • Katorza E, Pecht M, Apte RN, et al. Restoration of immunological responses by THF. a thymic hormone, in mice infected with murine cytomegalovirus (MCMV). Clin Exp Immunol 1987:70:268-75.
    • (1987) Clin Exp Immunol , vol.70 , pp. 268-275
    • Katorza, E.1    Pecht, M.2    Apte, R.N.3
  • 11
    • 0025335424 scopus 로고
    • Pecht M, Netzer L, et al. Immune modulation exerted by thymic humoral factor (THF-γ2). on T-cell subsets and IL-2 production of umbilical cord blood lymphocytes
    • Ben-Hur H. Pecht M, Netzer L, et al. Immune modulation exerted by thymic humoral factor (THF-γ2). on T-cell subsets and IL-2 production of umbilical cord blood lymphocytes. Immunopharmacol lmmunotoxicol 1990;12:123-33.
    • (1990) Immunopharmacol lmmunotoxicol , vol.12 , pp. 123-133
    • Ben-Hur, H.1
  • 12
    • 0027888223 scopus 로고
    • Potentiation of myeloid colony formation in bone marrow of intact and neonatallv thymectomized mice by the thymic hormone THF-γ2
    • Pecht M, Lourie S, Burstein Y, Zipori D, Trainin N. Potentiation of myeloid colony formation in bone marrow of intact and neonatallv thymectomized mice by the thymic hormone THF-γ2. Exp Hematol 1993;21:277-82.
    • (1993) Exp Hematol , vol.21 , pp. 277-282
    • Pecht, M.1    Lourie, S.2    Burstein, Y.3    Zipori, D.4    Trainin, N.5
  • 13
    • 0026599097 scopus 로고
    • Thymic humoral factor-γ2, an immunoregulatory peptide, enhances human hematopoietic progenitor cell growth
    • Barak Y, Hahn T, Pecht M, et al. Thymic humoral factor-γ2, an immunoregulatory peptide, enhances human hematopoietic progenitor cell growth. Exp Hematol 1992:20:173-7.
    • (1992) Exp Hematol , vol.20 , pp. 173-177
    • Barak, Y.1    Hahn, T.2    Pecht, M.3
  • 14
    • 0021832099 scopus 로고
    • Biological and clinical properties of THF
    • Trainili N, Handzel ZT, Pecht M. Biological and clinical properties of THF. Thymus 1995:7:137-50.
    • (1995) Thymus , vol.7 , pp. 137-150
    • Trainili, N.1    Handzel, Z.T.2    Pecht, M.3
  • 15
    • 0025353585 scopus 로고
    • Immunomodulation of T-cel 1 deficiency in humans by thymic humoral factor: From the crude extract to synthetic THF-γ2
    • Handzel ZT, Burstein Y, Buchner V, Pecht M, Trainin N. Immunomodulation of T-cel 1 deficiency in humans by thymic humoral factor: from the crude extract to synthetic THF-γ2. J Biol Response Mod 1990:9:269-78.
    • (1990) J Biol Response Mod , vol.9 , pp. 269-278
    • Handzel, Z.T.1    Burstein, Y.2    Buchner, V.3    Pecht, M.4    Trainin, N.5
  • 16
    • 0025184708 scopus 로고
    • Prospects of AIDS therapy by thymic humoral factor, a thymic hormone
    • Trainin N. Prospects of AIDS therapy by thymic humoral factor, a thymic hormone. Nat Immuri Cell Growth Regni 1990:9:155-9.
    • (1990) Nat Immuri Cell Growth Regni , vol.9 , pp. 155-159
    • Trainin, N.1
  • 17
    • 0024332917 scopus 로고
    • THF-γ2. a thymic hormone, increases immunocompetence and survival in 5-fluorouracil treated mice bearing MOPC-315 plasmacytoma
    • Ophir R, Pecht M, Halperin D, et al. THF-γ2. a thymic hormone, increases immunocompetence and survival in 5-fluorouracil treated mice bearing MOPC-315 plasmacytoma. Cancer Immunol Immunother 1989:30:119-25.
    • (1989) Cancer Immunol Immunother , vol.30 , pp. 119-125
    • Ophir, R.1    Pecht, M.2    Halperin, D.3
  • 18
    • 0025335004 scopus 로고
    • A synthetic thymic hormone, THF-γ2. repairs immunodeficiency of mice cured from plasmacytoma by melphalan
    • Ophir R, Pecht M, Rashid G, et al. A synthetic thymic hormone, THF-γ2. repairs immunodeficiency of mice cured from plasmacytoma by melphalan. Int. J Cancer 1990:45:1190-1.
    • (1990) Int. J Cancer , vol.45 , pp. 1190-1191
    • Ophir, R.1    Pecht, M.2    Rashid, G.3
  • 19
    • 0024998388 scopus 로고
    • THF-γ2, a synthetic thymic hormone, increases effectiveness of combined chemotherapy and immunotherapy against RPC-5 murine plasmacytoma
    • Ophir R, Pecht M, Relyveld FH, Burstein Y, Ben-Efraim S, Trainin N. THF-γ2, a synthetic thymic hormone, increases effectiveness of combined chemotherapy and immunotherapy against RPC-5 murine plasmacytoma. Int. J Immunopharmacol 1990:19: 751-4.
    • (1990) Int. J Immunopharmacol , vol.19 , pp. 751-754
    • Ophir, R.1    Pecht, M.2    Relyveld, F.H.3    Burstein, Y.4    Ben-Efraim, S.5    Trainin, N.6
  • 20
    • 0025877819 scopus 로고
    • Therapeutic effectiveness against MOPC-315 plasmacytoma of low or high doses of the synthetic thymic hormone THF-γ2 in combination with an immunomodulating or a nonimmunomodulating drug
    • Ophir R, Pecht M, Burstein Y, Harshemesh H, Ben-Efraim S, Trainin N. Therapeutic effectiveness against MOPC-315 plasmacytoma of low or high doses of the synthetic thymic hormone THF-γ2 in combination with an immunomodulating or a nonimmunomodulating drug. Int J Cancer 1991:48:96-100.
    • (1991) Int J Cancer , vol.48 , pp. 96-100
    • Ophir, R.1    Pecht, M.2    Burstein, Y.3    Harshemesh, H.4    Ben-Efraim, S.5    Trainin, N.6
  • 21
    • 0029893504 scopus 로고    scopus 로고
    • Thymic humoral factor-γ2 (THF-γ2) immunotherapy reduces the metastatic load and restores immunocompetence in 3LL tumor-bearing mice receiving anticancer chemotherapv
    • Ophir R, Pecht M, Keisari Y. et al. Thymic humoral factor-γ2 (THF-γ2) immunotherapy reduces the metastatic load and restores immunocompetence in 3LL tumor-bearing mice receiving anticancer chemotherapv. Immunopharmacol Immunotoxicol 1996:18: 209-36.
    • (1996) Immunopharmacol Immunotoxicol , vol.18 , pp. 209-236
    • Ophir, R.1    Pecht, M.2    Keisari, Y.3
  • 22
    • 0029860311 scopus 로고    scopus 로고
    • Pecht M, et al. Inhibition of murine Lewis lung carcinoma by combined chemotherapy and intranasal THF-γ2 immunotherapy
    • Rashid G, Ophir R. Pecht M, et al. Inhibition of murine Lewis lung carcinoma by combined chemotherapy and intranasal THF-γ2 immunotherapy. J Immunother 1996:19:324-33.
    • (1996) J Immunother , vol.19 , pp. 324-333
    • Rashid, G.1    Ophir, R.2
  • 24
    • 0025840165 scopus 로고
    • Immunity to melanoma in mice immunized w ith transfected allogeneic mouse fibroblasts expressing melanoma-associated antigens
    • Kim YS, Slomsky R, Cohen EP. Immunity to melanoma in mice immunized w ith transfected allogeneic mouse fibroblasts expressing melanoma-associated antigens. Cancer Immunol Immunother 1991:34:163-8.
    • (1991) Cancer Immunol Immunother , vol.34 , pp. 163-168
    • Kim, Y.S.1    Slomsky, R.2    Cohen, E.P.3
  • 25
    • 0026231180 scopus 로고
    • MHC class I genes controlling the metastatic phenotype of tumor cells
    • Feldman M, Eisenbach L. MHC class I genes controlling the metastatic phenotype of tumor cells. Semin Cancer Biol 1991:2:337-46.
    • (1991) Semin Cancer Biol , vol.2 , pp. 337-346
    • Feldman, M.1    Eisenbach, L.2
  • 26
    • 0025826349 scopus 로고
    • Immunization by gamma-IFN treated B 16-F10.9 melanoma cells protects against metastatic spread of the parental tumor
    • Porgador A, Brenner B, Vadai E, Feldman M, Eisenbach L. Immunization by gamma-IFN treated B 16-F10.9 melanoma cells protects against metastatic spread of the parental tumor, Int J Cancer (Suppl) 1991; 6:54-60.
    • (1991) Int J Cancer (Suppl) , vol.6 , pp. 54-60
    • Porgador, A.1    Brenner, B.2    Vadai, E.3    Feldman, M.4    Eisenbach, L.5
  • 28
    • 0008889843 scopus 로고
    • Reversal of the metastatic phenotype in Lewis lung carcinoma cells after transfection with syngeneic H-2Kb gene
    • Plaskin D, Gelber C, Feldman M, Eisenbach L. Reversal of the metastatic phenotype in Lewis lung carcinoma cells after transfection with syngeneic H-2Kb gene. Proc Natl Acad Sci USA 1988: 85:4463-7.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4463-4467
    • Plaskin, D.1    Gelber, C.2    Feldman, M.3    Eisenbach, L.4
  • 30
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983:65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 31
    • 0345214791 scopus 로고
    • Infection in cancer patients
    • Haskell CM, ed, Philadelphia: WB Saunders
    • Young LS. Infection in cancer patients. In: Haskell CM, ed. Cancer treatment. Philadelphia: WB Saunders. 1995:206-16.
    • (1995) Cancer treatment , pp. 206-216
    • Young, L.S.1
  • 32
    • 0029073706 scopus 로고
    • Chemoimmunotherapy of advanced malignant melanoma: Sequential administration of subcutaneous interleukin-2 and interferon-a after intra venous dacarbazine and carboplatin or intravenous dacarbazine, cisplatin. carmustine and tamoxifen
    • Atzpodien J, Lopez-Hanninen E, Kirchner H, et al. Chemoimmunotherapy of advanced malignant melanoma: sequential administration of subcutaneous interleukin-2 and interferon-a after intra venous dacarbazine and carboplatin or intravenous dacarbazine, cisplatin. carmustine and tamoxifen. EurJ Cancer 1995:31A:876-81.
    • (1995) EurJ Cancer , vol.31 A , pp. 876-881
    • Atzpodien, J.1    Lopez-Hanninen, E.2    Kirchner, H.3
  • 33
    • 0022178872 scopus 로고
    • The synergistic tumoricidal activity of anticancer drugs and oxidative burst-triggered macrophages
    • Marcovitch S, Keisari Y. The synergistic tumoricidal activity of anticancer drugs and oxidative burst-triggered macrophages. Cancer Immunol Immunother 1985:20:205-8.
    • (1985) Cancer Immunol Immunother , vol.20 , pp. 205-208
    • Marcovitch, S.1    Keisari, Y.2
  • 34
    • 0345646707 scopus 로고
    • Leukocytes in the lung
    • Massaro D, ed, New York-Basel: Marcel Dekker
    • Stein-Streilein J, Toews GS. Leukocytes in the lung. In: Massaro D, ed. Lung cell biology. New York-Basel: Marcel Dekker, 1989: 441-85.
    • (1989) Lung cell biology , pp. 441-485
    • Stein-Streilein, J.1    Toews, G.S.2
  • 35
    • 0024855217 scopus 로고
    • H-2Kb transfection of B16 melanoma cells results in reduced tumorigenidty and metastatic competence
    • Porgador A, Feldman M, Eisenbach L. H-2Kb transfection of B16 melanoma cells results in reduced tumorigenidty and metastatic competence. J Immunogenet 1989:16:291-303.
    • (1989) J Immunogenet , vol.16 , pp. 291-303
    • Porgador, A.1    Feldman, M.2    Eisenbach, L.3
  • 36
    • 0028871597 scopus 로고
    • Combined vaccination with major histocompatibility class I and interleukin 2 gene-transduced melanoma cells synergizes the cure of postsurgical established lung metastases
    • Porgador A, Tzehoval E, Vadai E, Feldman M, Eisenbach L. Combined vaccination with major histocompatibility class I and interleukin 2 gene-transduced melanoma cells synergizes the cure of postsurgical established lung metastases. Cancer Res 1995:55: 4941-9.
    • (1995) Cancer Res , vol.55 , pp. 4941-4949
    • Porgador, A.1    Tzehoval, E.2    Vadai, E.3    Feldman, M.4    Eisenbach, L.5
  • 37
    • 0029189838 scopus 로고
    • Foundations in cancer research. From Aristotle, through Spcmann. to tumor immunology: A personal experience
    • Feldman M. Foundations in cancer research. From Aristotle, through Spcmann. to tumor immunology: a personal experience. Adi Cancer Res 1995:66:41-70.
    • (1995) Adi Cancer Res , vol.66 , pp. 41-70
    • Feldman, M.1
  • 38
    • 0011987293 scopus 로고
    • Thymic humoral factor THF-γ2: An immunoregulatory octapeptide
    • Frensdorff A, ed, Tel Aviv: Tcl-Aviv University/Ramot Publishing
    • Trainin N, Pecht M, Burstein Y. Thymic humoral factor THF-γ2: an immunoregulatory octapeptide. In: Frensdorff A, ed. Frontiers in cancer research. Tel Aviv: Tcl-Aviv University/Ramot Publishing, 1994:263-81.
    • (1994) Frontiers in cancer research , pp. 263-281
    • Trainin, N.1    Pecht, M.2    Burstein, Y.3
  • 39
    • 0026510978 scopus 로고
    • Effect of synthetic thymic humoral factor (THF-γ2) on T cell activities in immunodeficient aging mice
    • Goso C, Frasca D, Doria G. Effect of synthetic thymic humoral factor (THF-γ2) on T cell activities in immunodeficient aging mice. Clin Exp Immunol 1992:87:346-51.
    • (1992) Clin Exp Immunol , vol.87 , pp. 346-351
    • Goso, C.1    Frasca, D.2    Doria, G.3
  • 40
    • 0015833549 scopus 로고
    • Studies on characterization of the lymphoid target cell for activity of a thymus humoral factor
    • Rotter V, Globerson A, Nakamura I, Trainin N. Studies on characterization of the lymphoid target cell for activity of a thymus humoral factor. J Exp Med 1973:138:130-42.
    • (1973) J Exp Med , vol.138 , pp. 130-142
    • Rotter, V.1    Globerson, A.2    Nakamura, I.3    Trainin, N.4
  • 41
    • 0028219408 scopus 로고
    • THF-γ2 stimulates cytokine release by peripheral blood mononuclear cells of patients w ith chronic hepatitis B virus infection
    • Daniels HM, O’Toole A, Hussein MJ, Corridori S, Alexander GJM, Williams R. THF-γ2 stimulates cytokine release by peripheral blood mononuclear cells of patients w ith chronic hepatitis B virus infection. J Hepatol 1994:20:370-5.
    • (1994) J Hepatol , vol.20 , pp. 370-375
    • Daniels, H.M.1    O’Toole, A.2    Hussein, M.J.3    Corridori, S.4    Alexander, G.J.M.5    Williams, R.6
  • 42
    • 0012008397 scopus 로고
    • The use of THF-γ2, a thymic hormone, for immunomodulation in cancer and AIDS
    • Lapis K. Ekhardt S. eds, Budapest: Lectures and symposia of the 14th International Cancer Congress
    • Trainin N, Burstein Y, Ben-Efraim S, Goebel FD, Handzel ZT. The use of THF-γ2, a thymic hormone, for immunomodulation in cancer and AIDS. In: Lapis K. Ekhardt S. eds. Novel approaches in cancer therapy. Budapest: Lectures and symposia of the 14th International Cancer Congress. 1987:253-66.
    • (1987) Novel approaches in cancer therapy , pp. 253-266
    • Trainin, N.1    Burstein, Y.2    Ben-Efraim, S.3    Goebel, F.D.4    Handzel, Z.T.5
  • 43
    • 0029066627 scopus 로고
    • Evaluation of efficacy and safety of thymus humoral factor-gamma 2 in the management of chronic hepatitis B
    • Farhat BA, Marinos G, Daniels HM, Naoumov NV, Williams R. Evaluation of efficacy and safety of thymus humoral factor-gamma 2 in the management of chronic hepatitis B. J Hepatol 1995:23: 21-7.
    • (1995) J Hepatol , vol.23 , pp. 21-27
    • Farhat, B.A.1    Marinos, G.2    Daniels, H.M.3    Naoumov, N.V.4    Williams, R.5
  • 44
    • 0025808686 scopus 로고
    • Interaction between thymic hormones and other immunomodulatory agents
    • Mastino A, Favalli C, Grelli S, Garaci E. Interaction between thymic hormones and other immunomodulatory agents. Ann 1st Super Sanita 1991:27:51-6.
    • (1991) Ann 1st Super Sanita , vol.27 , pp. 51-56
    • Mastino, A.1    Favalli, C.2    Grelli, S.3    Garaci, E.4
  • 45
    • 0028168087 scopus 로고
    • Cavaliere R, et al. Biochemistry with thymosin oil, interleukin-2 and dacarbazine in patients with metastatic melanoma: Clinical and immunological effects
    • Lopez M, Carpano S. Cavaliere R, et al. Biochemistry with thymosin oil, interleukin-2 and dacarbazine in patients with metastatic melanoma: clinical and immunological effects. Ann Oncol 1994: 5:741-6.
    • (1994) Ann Oncol , vol.5 , pp. 741-746
    • Lopez, M.1    Carpano, S.2
  • 46
    • 0024585413 scopus 로고
    • Thymic hormone in the treatment of cancer
    • Mitchell MS. ed. Immunity to cancer 11
    • Dardenne M, Bach JF. Thymic hormone in the treatment of cancer. In: Mitchell MS. ed. Immunity to cancer 11. Progr Clin lliol Res 1987:288:363-82.
    • (1987) Progr Clin lliol Res , vol.288 , pp. 363-382
    • Dardenne, M.1    Bach, J.F.2
  • 47
    • 0030943874 scopus 로고    scopus 로고
    • Thymus therapy for cancer? A criteria-based. systematic review
    • Ernst E. Thymus therapy for cancer? A criteria-based. systematic review. Eur J Cancer 1997:33:531-5.
    • (1997) Eur J Cancer , vol.33 , pp. 531-535
    • Ernst, E.1
  • 48
    • 0023805361 scopus 로고
    • Hegarty J, et al. In vitro effect of TP-1 (a calf thymic extract) on suppressor T-cell function of patients with autoimmune chronic active hepatitis
    • O’Brein CJ, Nouri-Aria KT. Hegarty J, et al. In vitro effect of TP-1 (a calf thymic extract) on suppressor T-cell function of patients with autoimmune chronic active hepatitis. Int J Immunopharmacol 1988:10:651-6.
    • (1988) Int J Immunopharmacol , vol.10 , pp. 651-656
    • O’Brein, C.J.1    Nouri-Aria, K.T.2
  • 49
    • 0024389450 scopus 로고
    • A comparative study on the immunological effects of bovine and porcine thymic extracts: Induction of lymphoproliferative response and enhancement of interleukin-2, gamma interferon and tumor necrotic factor production in vitro on cord blood lymphocytes
    • Lin CY, Low TL. A comparative study on the immunological effects of bovine and porcine thymic extracts: induction of lymphoproliferative response and enhancement of interleukin-2, gamma interferon and tumor necrotic factor production in vitro on cord blood lymphocytes. Immunopharmacology 1989:18:1-10.
    • (1989) Immunopharmacology , vol.18 , pp. 1-10
    • Lin, C.Y.1    Low, T.L.2
  • 50
    • 0025362706 scopus 로고
    • Thymosin alpha-1 enhancement of human lymphocyte proliferation is not mediated by prostaglandin E2
    • Colarian J, Sethi A, Merchant A, Parikh N, Mutchnik M. Thymosin alpha-1 enhancement of human lymphocyte proliferation is not mediated by prostaglandin E2. Thymus 1990:15:241-7.
    • (1990) Thymus , vol.15 , pp. 241-247
    • Colarian, J.1    Sethi, A.2    Merchant, A.3    Parikh, N.4    Mutchnik, M.5
  • 51
    • 0025019511 scopus 로고
    • Thymosin alpha-1 modulates the expression of high affinity interleukin-2 receptors on normal human lymphocytes
    • Leichtling KD, Serrata SA, Sztein MB. Thymosin alpha-1 modulates the expression of high affinity interleukin-2 receptors on normal human lymphocytes. Int J Immunopharmacol 1990:12:19-29.
    • (1990) Int J Immunopharmacol , vol.12 , pp. 19-29
    • Leichtling, K.D.1    Serrata, S.A.2    Sztein, M.B.3


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