Identification of quantitative trait loci influencing traits related to energy balance in selection and inbred lines of mice

Genetics

Volumn 152, Issue 2, 1999, Pages 699-711

  Moody, D E ^a   Pomp, D ^b   Nielsen, M K ^a   Van Vleck, L D ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b U S MEAT ANIMAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BODY WEIGHT; CHROMOSOME 1; CHROMOSOME 2; CHROMOSOME 3; CHROMOSOME 7; ENERGY BALANCE; ENERGY EXPENDITURE; FEMALE; GENE LOCATION; GENE LOCUS; GENETIC SELECTION; HEAT LOSS; INBRED STRAIN; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SUBCUTANEOUS FAT;

ADIPOSE TISSUE; ALLELES; ANIMALS; BODY WEIGHT; CHROMOSOME MAPPING; CROSSES, GENETIC; ENERGY INTAKE; ENERGY METABOLISM; FEMALE; GENOTYPE; LOD SCORE; MALE; MICE; MICE, INBRED ICR; MICE, INBRED STRAINS; MICROSATELLITE REPEATS; PHENOTYPE; QUANTITATIVE TRAIT, HERITABLE; SELECTION (GENETICS);

RODENTIA;

EID: 0033051920     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. ANDERSSON, L., C. S. HAIKY, H. EIIKGRKN,S. A. KXOTT, MJUIIANSSON et al., 1994 Genetic mapping of quantitative trait loci for growth and fatness in pigs. Science 263: 1771-1774.
2. BOIDMAN, K. G., L. A. KRIESK, L. D. VAN VIFCK, C. P. VAN TASSEII, and S. D. KACIIMAN, 1995 A manual for use of MTDFREML. A set of programs to obtain estimates of variances and covariances [DRAFT]. U. S. Department of Agriculture, Agricultural Research Service, Clay Center, NE.
3. Boss, O., S. SAMFC, A. PAOIONI-GIACOBINO, C. ROSSIKR, A. DUIIOO el al., 1997 Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408: 39-42.
4. BOUCIIARD, C., L. PKRUSSK, Y. C. CIIAONON, C. \\'ARDKN and D. RicQUIFR, 1997 Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans. Hum. Mol. Genet. 6: 1887-1889.
5. CASSARIVDOUICIER, A. M., M. I-XROSE, J. C. MATAMAI-A, O. ClIAMrirNY, F. BOUIII-\UD et al, 1994 In vitro interactions between nuclear proteins and uncoupling protein gene promoter reveal several putative transactivating factors including Etsl, retinoid X receptor, thyroid hormone receptor, and a CACCC box-binding protein. J. Biol. Chem. 269: 24335-24342.
6. CHURCHILL, G. A., and R. W. DOERGE, 1994 Empirical threshold values for quantitative trait mapping. Genetics 138: 963-971.
7. ENERBACK, S., A. JACOBSSON, E. M. SIMPSON, C. GUKRRA, H. YAMASIIITA et al, 1997 Mice lacking mitochoudrial uncoupling protein arc cold-sensitive but not obese. Nature 387: 90-94.
8. FALCONER, D. S., and T. F. C. MACKAY, 1996 Introduction to Quantitative Genetics. Longman Group Limited, Essex, England.
9. FIEURY, C., M. NEVEROVA, S. COIIINS, S. RAIMBAUIT, O. CHAMPIGNY el al, 1997 Uncoupling protcin-2: a novel gene linked to obesity and hyperinsulinemia. Nat. Genet. 15: 269-272.
10. GREEN, P. K., and S. CROOKS, 1990 Documentation for CRI-MAP, version 24. Washington University School of Medicine, St. Louis.
11. GRIFFITHS, M., P. R. PAYNE, A. J. STUNKAKDJ. P. W. RIVERS and M. Cox, 1990 Metabolic rate and physical development in children at risk of obesity. Lancet 336: 76-78.
12. HAIEY, C. S., and S. A. KNOTT, 1992 A simple regression method for interval mapping in line crosses. Heredity 69: 315-324.
13. HAIEY, C. S., S. A. KNOTT andj. M. EISON, 1994 Mapping quantita-live trait loci in crosses between outbred lines using least squares. Genetics 136: 1195-1207.
14. HIMMS-HACKN,J., 1989 Role of thcrmogcnesis in the regulation of energy balance in relation to obesity. Can. J. Physiol. Pharmacol. 67: 394-401.
15. JONES, L. D., M. K. NIEISEN and R. A. BRITTON, 1992 Genetic variation in liver mass, body mass, and liver:body mass in mice. J. Anim. Sei. 70: 2999-3006.
16. LANDER, E. S., and D. BOTSTEIN, 1989 Mapping Mendelian factors underlying quantitative traits using RFLP maps. Genetics 121: 185-199.
17. LANDER, E. S., and L. KRUGIYAK, 1995 Genetic dissection of complex traits-guidelines for interpreting and reporting linkage results. Nat. Genet. 11:241-247.
18. LINCOLN, S., M. DAIY and E. S. I-ANDKR, 1992 Constructing genetic maps with MAPMAKER/EXP 30. Technical report. Whitehead Institute Technical Report, Cambridge, MA.
19. MOODY, D. E., D. POMP and M. K. NIEISEN, 1997 Variability in metabolic rate, feed intake and fatness among selection and inbred lines of mice. Genet. Res. 70: 225-235.
20. MOUSKI., M. R., 1998 Daily activity and core body temperature of mice selected for high and low heat loss. MS. Thesis, University of Nebraska, Lincoln.
21. NAKAMURA, M., Y. AOKI and D. HIRANO, 1996 Cloning and functional expression of a cDNA encoding a mouse type 2 neuropeptide Y receptor. Biochim. Biophys. Acta 1284: 134-137.
22. NAYLOR, S. L., A. Y. SAKAGUCIII, L. McDoNAiD, S. TODD, P. A. LAIIKY el al., 1986 Mapping thyrotropin beta subunit gene in mouse and man. Somat. Cell Mol. Genet. 12: 307-311.
23. NIKISKN, M. K., L. D. JONES, B. A. FKEKING andj. A. DESIIAZER, 1997a Divergent selection for heat loss in mice: I. Selection applied and direct response through fifteen generations. J. Anim. Sei. 75: 1461-1468.
24. NIEISEN, M. K., B. A. FKEKING, L. D. JONES, S. M. NELSON, T. L. VORDERSTRASSE et al., 1997b Divergent selection for heat loss in mice: II. Correlated responses in feed intake, body mass, body composition, and number born through fifteen generations. J. Anim. Sei. 75: 1469-1476.
25. NORMAN, R. A., P. A. TATARANNI, R. PRATIKY, D. B. THOMPSON. R. L. HANSON et al., 1998 Aiitosomal genome scan for loci linked to obesity and energy metabolism in Pima Indians. Am. J. Hum. Genet. 62: 659-668.
26. POMP, D., 1997 Genetic dissection of obesity in polygenic animal . models. Behav. Genet. 27: 285-305.
27. POMP, D., and M. K. NIEISEN, 1999 Quantitative genetics of energy balance-lessons from animal models. Obesity Res. 7: 106-110.
28. RXVUSSIN, E., S. LIIIIOJA, W. C. KNOWIKR, L. CHRISTIN, D. FKEYMOND et al., 1988 Reduced rate of energy expenditure as a risk factor for body-weight gain. N. Engl. J. Med. 318: 467-472.
29. RICE, T., A. TREMBIAY, O. DERIAZ, L. PERUSSE, D. C. R\o el al., 1996 Genetic pleiotropy for resting metabolic rate with fat-free mass and fat mass: the Quebec family study. Obesity Res. 4: 125-131.
30. ROBERTS, S. B., J. SAVAGE, \V. A. COWARD, B. CHEW and A. LUCAS, 1988 Energy expenditure and intake in infants born to lean and overweight mothers. N. Engl. J. Med. 318: 461-4G6.
31. SALTZMAN, E., and S. B. ROBERTS, 1995 The role of energy expenditure in energy regulation: findings from a decade of research. Nntr. Rev. 53: 209-220.
32. SAS, 1988 SAS/STAT User's Guide, Release 603. SAS Institute, Gary, NC.
33. TAYIOR, B. A., and SJ. PHILLIPS, 1996 Detection of obesity QTLs on mouse chromosomes 1 and 7 by selective DNA pooling. Genomics 34: 389-398.
34. THOMAS, S. A., and R. D. PAIMITER, 1997 Thermorcgulatoiy and metabolic phenotypes of mice lacking noradrenaline and adrenaline. Nature 387: 94-97.
35. ViDAi-Puio, A., G. SOIANES, D. GRUJICJ. S. FLIER and B. B. LOWEIL, 1997 UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem. Biophys. Res. Commun. 235: 79-82.
36. WARDEN, C. H., J. S. FISIER, S. M. SHOEMAKER, P. Z. WEN, K. L. SVKBSIII et al., 1995 Identification of four chromosomal loci determining obesity in a multifactorial mouse model. J. Clin. Invest. 95: 1545-1552.
37. WEST, D. B., G. E. TRUKTT, J. GOUDEY-LEFEVRE and K. B. YORK, 1995 Loci on chromosomes 4, 7, 9, 12, & 15 control a significant proportion of the dietary obesity phenot)pc in the mouse. FASER J. 9(3): A722.
38. WOODS, S. C., R. J. SEEIKV, D. PORTK, JR. and M. W. SCIIWARTZ, 1998 Signals that regulate food intake and energy homeostasis. Science 280: 1378-1383.
39. ZKNG, Z-B., 1993 Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci. Proc. Nail. Acad. Sei. USA 90: 10972-10976.