The exposure assessment for veterinary medicinal products

Science of the Total Environment

Volumn 225, Issue 1-2, 1999, Pages 119-133

  Montforts, Mark H M M ^a   Kalf, Dennis F ^a   Van Vlaardingen, Peter L A ^a   Linders, Jan B H J ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Exposure assessment; Hazard assessment; Veterinary products

Indexed keywords

VETERINARY DRUG;

ARTICLE; DRUG DETERMINATION; DRUG EXCRETION; ENVIRONMENTAL IMPACT ASSESSMENT; NETHERLANDS; NONHUMAN; POLLUTION; PRIORITY JOURNAL; RISK ASSESSMENT;

AGRICULTURE; ANIMAL HUSBANDRY; ANIMALS; CATTLE; ENVIRONMENTAL EXPOSURE; FISHES; MANURE; NETHERLANDS; RISK ASSESSMENT; RISK MANAGEMENT; VETERINARY DRUGS;

EID: 0033051706     PISSN: 00489697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0048-9697(98)00338-6     Document Type: Article

References (32)

1. Bryan GW, Gibbs PE, Hummerstone LG, Burt GR The decline of the gastropod Nucella lapillus around south-west England: evidence for the effect of tributyltin from antifouling paints. J Mar Biol Assoc UK. 66:1986;611-640.
2. Campbell WC. Ivermectin and abamectin. Berlin: Springer Verlag, 1989.
3. CBS. De landbouwtelling 1996 (in Dutch). Centraal Bureau voor de Statistiek. Misset uitgeverij B.V., Doetinchem, 1996.
4. ECB. EUSES, the European Union System for the evaluation of substances. National Institute of Public Health and the Environment (RIVM), The Netherlands. Available from European Chemicals Bureau (ECB/DGXI), Ispra, Italy, 1996a.
5. ECB. Technical Guidance Document in support of the commission directive 93/67/EEC on risk assessment for new notified substances and the commission regulation (EC) 1488/94 on risk assessment for existing substances. Ispra, Italy: European Chemical Bureau, 1996b.
6. EMEA. Note for guidance: environmental risk assessment for veterinary medicinal products other than GMO-containing and immunological products. European Agency for Evaluation of Medicinal Products, Committee for veterinary medicinal products, EMEA/CVMP/055/96, 1997.
7. EU. Directive 81/852/EEC of the Commission of September 28, 1981 as published in the Official Journal of the European Community of November 6, 1981, No. L317, p. 16, amended by: Directive 92/18/EEC of the Commission of March 20, 1992 as published in the Official Journal of the European Community of April 10, 1992, No. L97, p. 1; and Directive 93/40/EEC of the Council of June 14, 1993 as published in the Official Journal of the European Community of August 24, 1993, No. L214, p. 31.
8. EU. Directive 81/852/EEC of the Commission of September 28, 1981 as published in the Official Journal of the European Community of November 6, 1981, No. L317, p. 16, amended by: Directive 92/18/EEC of the Commission of March 20, 1992 as published in the Official Journal of the European Community of April 10, 1992, No. L97, p. 1; and Directive 93/40/EEC of the Council of June 14, 1993 as published in the Official Journal of the European Community of August 24, 1993, No. L214, p. 31.
9. EU. Directive 81/852/EEC of the Commission of September 28, 1981 as published in the Official Journal of the European Community of November 6, 1981, No. L317, p. 16, amended by: Directive 92/18/EEC of the Commission of March 20, 1992 as published in the Official Journal of the European Community of April 10, 1992, No. L97, p. 1; and Directive 93/40/EEC of the Council of June 14, 1993 as published in the Official Journal of the European Community of August 24, 1993, No. L214, p. 31.
10. EU. Directive 91/414/EEC of 15 July 1991 concerning the placing of plant protection products on the market, O.J. No L230, 19.8.1991 as lastly amended by: Directive 97/57/EC establishing Annex VI to Directive 91/414/EEC O.J. No. L265, 27.9.1997, 1997a.
11. EU. Directive 91/414/EEC of 15 July 1991 concerning the placing of plant protection products on the market, O.J. No L230, 19.8.1991 as lastly amended by: Directive 97/57/EC establishing Annex VI to Directive 91/414/EEC O.J. No. L265, 27.9.1997, 1997a.
12. EU. Directive of the European Parliament and of the Council concerning the placing of biocidal products on the market: joint text (doc. PE-CONS 3633/97 ENV394 ENT183 CODEC681) adopted by the Council on 18, 19 December 1997, 1997b.
13. Halley BA, Jacob ThA, Lu AYH The environmental impact of the use of ivermectin: environmental effects and fate. Chemosphere. 18:1989;1543-1563.
14. Herd R Endectocidal drugs: ecological risks and counter-measures. Int J Parasit. 25:1995;875-885.
15. Kamstra A, Van Der Heul JW. Afvalwater van viskwekerijen (in Dutch). RIVO-DLO, report CO04/95, IJmuiden, The Netherlands, 1995.
16. Linders JBHJ, Jager DT, editors. USES 2.0 The uniform system for the evaluation of substances, version 2.0. The Netherlands' supplement to EUSES. RIVM, Report no. 679102037. Bilthoven, The Netherlands, 1997.
17. Lumaret J, Galante E, Lumbreras C, Mena J, Bertrand M, Bernal JL, Cooper JF, Kadiri N, Crowe D Field effects of ivermectin residues on dung beetles. J Appl Ecol. 30:1993;428-436.
18. Marsh R, Campling RC Fouling of pastures by dung. Herbage Abst. 4:1970;123-130.
19. MacKay D, Bobra A, Shiu WY Relationship between aqueous solubility and octanol-water partition coefficients. Chemosphere. 9:1980;701-711.
20. Mensink BJWG, Montforts MHMM, Wijkhuizen-Maslankiewicz L, Tibosch H, Linders JBHJ. Manual for summarising and evaluating the environmental aspects of pesticides. RIVM, report 679101022. Bilthoven, The Netherlands, 1995.
21. Montforts MHMM. Environmental risk assessment for veterinary medicinal products. 1. Other than GMO-containing and immunological products. RIVM, Report 613310001. Bilthoven, The Netherlands, 1997.
22. RIVM, VROM, VWS. Uniform system for the evaluation of substances, version 1.0, distribution no. 11144/150. The Hague: Ministry of Public Housing, Spatial Planning and Environment, 1994.
23. Roij ThAMJ, De Vries PHU. Milieutoxicologische aspecten van het gebruik van veevoederadditieven en therapeutica. Persistentie in dierlijke excreta en milieu (in Dutch). The Hague: Ministry of Housing, Spatial Planning and the Environment, 1980.
24. Sommer C, Steffansen B Changes with time after treatment in the concentrations of ivermectin in fresh cow dung and in cow pats aged in the field. Vet Parasit. 48:1993;67-73.
25. Soulides DA, Pinck LA, Allison FE. Antibiotics in soils: V. Stability and release of soil adsorbed antibiotics. Antibiot Soils 1962:239-244.
26. Spaepen KRI, van Leemput LJJ, Wislocki PG, Verschueren C A uniform procedure to estimate the predicted environmental concentration of the residues of veterinary medicines in soil. Environ Toxicol Chem. 16:1997;1977-1982.
27. Strong L, James S Some effects of ivermectin on the yellow dung fly Scatophaga stercoraria. Vet Parasit. 48:1993;181-191.
28. Strong L, Wall R, Woolford A, Djeddour D The effect of faecally excreted ivermectin and fenbendazole on the insect colonisation of cattle dung following the oral administration of sustained-release bolus. Vet Parasit. 2:1996;253-266.
29. Struijs J, Stoltenkamp J, Van De Meent D A spreadsheet-based box model to predict the fate of xenobiotics in a municipal wastewater treatment plant. Water Res. 25:1991;891-900.
30. Stumpf M, Ternes ThA, Haber K, Baumann W Nachweis von natürlichen und synthetischen Östrogenen in Kläranlagen und Fliessgewässern (in German, abstract in English). Vom Wasser. 87:1996;251-261.
31. Van Leeuwen CJ. General introduction. In: Van Leeuwen CJ, Hermens JLM, editors. Risk assessment of chemicals: an introduction. Dordrecht: Kluwer, 1995:1-18.
32. Wardhaugh KG, Rodriguez-Menendez H The effect of the antiparasitic drug, ivermectin, on the development and survival of the dung breeding fly Orthelia cornicia and the scarabeine dung beetles, Copris hispanus, Bubas bubalus and Onitis belial. J Appl Entomol. 106:1988;381-389.