Pre- and postprandial expression of the leptin receptor splice variants OB-Ra and OB-Rb in murine peripheral tissues

Physiological Research

Volumn 48, Issue 3, 1999, Pages 189-195

  Fruhbeck G ^a   Gomez Ambrosi J ^a   Martinez J A ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Fasting; Fiber type composition; Mice; OB Protein; Skeletal muscle

Indexed keywords

LEPTIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; GASTROCNEMIUS MUSCLE; KIDNEY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SOLEUS MUSCLE; TESTIS; TISSUE DISTRIBUTION;

ANIMALS; CARRIER PROTEINS; LEPTIN; MALE; MICE; ORGAN SPECIFICITY; POSTPRANDIAL PERIOD; PROTEIN ISOFORMS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOKINE; RNA SPLICING;

EID: 0033051202     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. AHIMA RS, PRABAKARAN D, MANTZOROS C, QU D, LOWELL B, MARATOS-FLIER E, FLIER JS: Role of leptin in the neuroendocrine response to fasting. Nature 382: 250-252, 1996.
2. CIOFFI JA, SHAFER AW, ZUPANCIC TJ, SMITH-GBUR J, MIKHAIL A, PLATIKA D, SNODGRASS HR: Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction. Nature Med 2: 585-589, 1996.
3. DYER CJ, SIMMONS JM, MATTERI RL, KEISLER DH: Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissues and is differentially expressed in hypothalamic regions of well-fed and feed-restricted ewes. Domest Anim Endocrinol 14: 119-128, 1997.
4. HÄMÄLÄINEN N, PETTE D: The histochemical profiles of fast fiber types IIB, IID, and IIA in skeletal muscles of mouse, rat, and rabbit. J Histochem Cytochem 41: 733-743, 1993.
5. HOGGARD N, MERCER JG, RAYNER DV, MOAR K, TRAYHURN P, WILLIAMS LM: Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization. Biochem Biophys Res Commun 232: 383-387, 1997.
6. HUANG XF, LIN S, ZHANG R: Upregulation of leptin receptor mRNA expression in obese mouse brain. Neuroreport 8: 1035-1038, 1997.
7. JOHNSON MA: Skeletal muscle. In: Histochemistry in Pathology. MI FILIPE, BD LAKE (eds), Churchill Livingstone, London, 1990, pp 129-157.
8. KOLACZYNSKI JW, CONSIDINE RV, OHANNESIAN J, MARCO C, OPENTANOVA I, NYCE MR, MYINT M, CARO JF: Responses of leptin to short-term fasting and refeeding in humans. A link with ketogenesis but not ketones themselves. Diabetes 45: 1511-1515, 1996.
9. LEE G-H, PROENCA R, MONTEZ JM, CARROLL KM, DARVISHZADEH JG, LEE JI, FRIEDMAN JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 379: 632-635, 1996.
10. LIN S, HUANG XF: Fasting increases leptin receptor mRNA expression in lean but not obese (ob/ob) mouse brain. Neuroreport 8: 3625-3629, 1997.
11. MACDOUGALD OA, HWANG C-S, FAN H, LANE MD: Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-1 adipocytes. Proc Natl Acad Sci USA 92 9034-9037, 1995.
12. SALADIN R, DE VOS P, GUERRE-MILLO M, LETURQUE A, GIRARD J, STAELS B, AUWERX J: Transient increase in obese gene expression after food intake or insulin administration. Nature 377: 527-529, 1995.
13. TARTAGLIA LA, DEMBSKI M, WENG X, DENG N, CULPEPPER J, DEVOS R, RICHARDS GJ, CAMPFIELD LA, CLARK FT, DEEDS J et al.: Identification and expression cloning of a leptin receptor, OB-R. Cell 83: 1263-1271, 1995.
14. TRAYHURN P: New insights into the development of obesity: obese genes and the leptin system. Proc Nutr Soc 55: 733-791, 1996.
15. TRAYHURN P, THOMAS ME, DUNCAN JS, RAYNER DV: Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice. FEBS Lett 368: 488-490, 1995.
16. ZAMORANO PL, MAHESH VB, DE SEVILLA LM, CHORICH LP, BHAT GK, BRANN DW: Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat. Neuroendocrinology 65: 223-228, 1997.