Differential distribution of dystrophins in rat retina

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 7, 1999, Pages 1520-1529

  Claudepierre, Thomas ^a   Rodius, François ^b   Frasson, Maria ^a   Fontaine, Valérie ^a   Picaud, Serge ^a   Dreyfus, Henri ^a   Mornet, Dominique ^c   Rendon, Alvaro ^a  

^a UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^b Ctr des Sciences de l'Environnement   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DYSTROPHIN;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; ELECTRORETINOGRAPHY; EYE DEVELOPMENT; GENE EXPRESSION REGULATION; GENETIC DISORDER; GLIA CELL; MUELLER CELL; MUSCULAR DYSTROPHY; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RETINA;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; DNA PRIMERS; DYSTROPHIN; ELECTRORETINOGRAPHY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; MALE; NEUROGLIA; PHOTORECEPTORS, VERTEBRATE; POLYMERASE CHAIN REACTION; RATS; RATS, MUTANT STRAINS; RATS, WISTAR; RETINA; RETINAL DEGENERATION; RNA, MESSENGER;

EID: 0033050409     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Hoffmann EP, Brown RHJ, Kunkel LM. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell. 1987; 51:919-928.
2. Koenig M, Monaco AP, Kunkel LM. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell. 1988; 53:219-226.
3. Suzuki A, Yoshida M, Yamamoto H, Ozawa E. Glycoprotein-binding site of dystrophin is confined to the cysteine-rich domain and the first half of the carboxy-terminal domain. FEBS Lett. 1992;308: 154-160.
4. Love DR, Hill DF, Dickson G, et al. An autosomal transcript in skeletal muscle with homology with dystrophin. Nature. 1989;33: 55-58.
5. Cox GA, Phelps SF, Chapman VM, Chamberlain JS. New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin. Nat Genet. 1993;4:87-93.
6. Bar S, Barnea E, Levy Z, Neuman S, Yaffe D, Nudel U. A novel product of the Duchenne muscular dystrophy gene which greatly differs from the known isoforms in its structure and tissue distribution. Biochem J. 1990;272:557-560.
7. Rapaport D, Lederfein D, den Dunnen JT, et al. Characterization and cell type distribution of a novel major transcript of the Duchenne Muscular Dystrophy gene. Differentia. 1992;49:187-193.
8. Byers TJ, Lidov HGW, Kunkel LM. An alternative dystrophin transcript specific to peripheral nerve. Nat Genet. 1993;4:77-81.
9. Lidov HGW, Selig S, Kunkel LM. Dp140: a novel 140 kDa CNS transcript from the dystrophin locus. Hum Mol Genet. 1995;4: 329-335.
10. D'Souza V, Man N, Morris GE, Karges W, Pillers DM, Ray PA. Novel dystrophin isoform is required for normal retinal electrophysiology. Hum Mol Genet. 1995;4:837-842.
11. Austin RC, Howard PL, D'Souza V, Klamut HJ, Ray PN. Cloning and characterization of alternatively spliced isoforms of Dp71. Hum Mol Genet. 1995;4:1475-1483.
12. Blake DJ, Schofield JN, Zuellig RA, et al. G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain. Proc Natl Acad Sci USA. 1995;92:3697-3701.
13. Roberts RG, Freeman TC, Kendall E, et al. Characterization of DRP2, a novel human dystrophin homologue. Nat Genet. 1996; 13:223-226.
14. Billard C, Gillet P, Signoret JL, et al. Cognitive functions in Duchenne muscular dystrophy: a reappraisal and comparison with spinal muscular atrophy. Neuromuscul Disord. 1992;2:371-378.
15. Bushby KM, Appleton R, Anderson LV, Welch JL, Kelly P, Gardner-Medwin D. Deletion status and intellectual impairment in Duchenne muscular dystrophy. Dev Med Child Neurol. 1995;37:260-269.
16. Lenk U, Hanke R, Thiele H, Speer A. Point mutations at the carboxy terminus of the human dystrophin gene: implications for an association with mental retardation in DMD patients. Hum Mol Genet. 1993;2:1877-1881.
17. Rodius F, Claudepierre T, Rosas-Vargas H, et al. Dystrophins in developing retina: Dp260 expression correlates with synaptic maturation. Neuroreport. 1997;8:2383-2387.
18. Pillers DM, Bulman DE, Weleber RG, et al. Dystrophin expression in the human retina is required for normal function as defined by electroretinography. Nat Genet. 1993;4:82-86.
19. Cibis GW, Fitzgerald KM, Harris DJ, Rothberg PJ, Rupani M. The effects of dystrophin gene mutations on the ERG in mice and humans. Invest Ophthalmol Vis Sci. 1993;34:3646-3652.
20. Fitzgerald KM, Cibis GW, Giambrone SA, Harris DJ. Retinal signal transmission in Duchenne muscular dystrophy: evidence for dysfunction in the photoreceptor/depolarizing bipolar cell pathway. J Clin Invest. 1994;93:2425-2430.
21. Sigesmund DA, Weleber RG, Pillers DM, et al. Characterization of the ocular phenotype of Duchenne and Becker muscular dystrophy. Ophthalmology. 1994;101:856-865.
22. DeBecker I, Riddell DC, Dooley JM, Tremblay F. Correlation between electroretinogram findings and molecular analysis in the Duchenne muscular dystrophy phenotype. Br J Ophthalmol. 1994;78:719-722.
23. cv3 Mouse is a model for electroretinography of Duthenne/Becker muscular dystrophy. Invest Ophthalmol Vis Sci. 1995;36:462-466.
24. Stockton RA, Slaughter MM. B-wave of the electroretinogram: a reflection of ON bipolar cell activity. J Gen Physiol. 1989;93:101-122.
25. + hypothesis. J Neurophysiol. 1984;51: 164-182.
26. Schmitz F, Holbach M, Drenckhahn D. Colocalization of retinal dystrophin and actin in postsynaptic dendrites of rod and cone photoreceptor synapses. Histochemistry. 1993;100:473-479.
27. Montanaro F, Carbonetto S, Campbell KP, Lindenbaum M. Dystroglycan expression in the wild type and mdx mouse neural retina: synaptic colocalization with dystrophin, dystrophin-related protein but not laminin. J Neurosci Res. 1995;42:528-538.
28. Drenckhahn D, Holbach M, Ness W, Schmitz F, Anderson LVB. Dystrophin and the dystrophin-associated glycoprotein, δ-dystroglycan, co-localize in the photoreceptor synaptic complexes of the human retina. Neuroscience. 1996;73:605-612.
29. Ueda H, Kohayashi T, Mitsui K, Tsurugi K, Tsukahara S, Ohno S. Dystrophin localization at presynapse in rat retina revealed by immunoelectron microscopy. Invest Ophthalmol Vis Sci. 1995;36: 2318-2322.
30. Ueda H, Kato Y, Baba T, et al. Immunocytochemical study of dystrophin localization in cone cells of mouse retinas. Invest Ophthalmol Vis Sci. 1997;38:1627-1630.
31. Ueda H. Baba T, Terada N, Kato Y, Tsukahara S, Ohno S. Dystrophin in rod spherules: submembranous dense regions facing bipolar cell processes. Histochem Cell Biol. 1997;108:243-248.
32. Schmitz F, Drenckhahn D. Localization of dystrophin and beta-dystroglycan in bovine retinal photoreceptor processes extending into the postsynaptic dendritic complex. Histochem Cell Biol. 1997;108:249-255.
33. Howard PL, Dally GY, Wong MH, et al. Localization of dystrophin isoform Dp71 to the inner limiting membrane of the retina suggests a unique functional contribution of Dp71 in the retina. Hum Mol Genet. 1998;7:1385-1391.
34. Dowling JE, Sidman RL. Inherited retinal dystrophy in the rat. J Cell Biol. 1962;14:73-109.
35. Dreyfus H, Guérold B, Fontaine V, Sahel J, Hicks D. Simplified ganglioside composition of pholoreceptors compared to other retinal neurons. Invest Ophthalmoh Vis Sci. 1996;37:574-585.
36. Grant GB, Werblin FS. Low-cost data acquisition and analysis programs for electrophysiology. J Neurosci Methods. 1994;55:89-98.
37. Chomczynski P, Sacchi N. Single-slep method of RNA isolation by acid guanidium thyocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
38. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1970;72:248-254.
39. Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature. 1970;227:680-685.
40. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA. 1979;76:4350-4354.
41. Léger JJ, Augier N, Léger J, Mornet D, Pons F. La ou les dystrophine(s), trois années après leur découverte. Med Sci. 1991;7:805-819.
42. Fabbrizio E, Léger J, Anoal M, Léger JJ, Mornet D. Monoclonal antibodies targeted against the C terminal domain of dystrophin or utrophin. FEBS Lett. 1993;1:10-14.
43. Kaitz M, Auerbach E. Effect of early and late light exposure on the inherited retinal degeneration in rats. Exp Eye Res. 1978;26:699-704.
44. Nomura A, Shigemoto R, Nakamura Y, Okamoto N, Mizuno N, Nakanishi S. Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell. 1994;77:361-369.
45. Dixon AK, Tait TM, Campbell EA, Bobrow M, Roberts RG, Freeman TC. Expression of the dystrophin-related protein 2 (DRP2) transcript in mouse. J Mol Biol. 1997;270:551-558.
46. Roque RS, Caldwell RB. Müller cell changes precede vascularization of the pigment epithelium in the dystrophic rat retina. Glia. 1990;3:464-475.
47. Kameya S, Araki E, Katsuki M, et al. Dp260 disrupted mice revealed prolonged implicit time of the b-wave in ERG and loss of accumulation of beta-dystroglycan in the outer plexiform layer of the retina. Hum Mol Genet. 1997;6:2195-2203.
48. Schofield JN, Blake DJ, Simmons C, et al. Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines. Hum Mol Genet. 1994;3:1309-1316.
49. Caldwell RB, Roque RS, Solomon SW. Increased vascular density and vitreo-retinal membranes accompany vascularization of the pigment epithelium in the dystrophic rat retina. Curr Eye Res. 1989;8:923-937.
50. Fassina G, Aluigi MG, Gentleman S, et al. The cAMP analog 8-Cl-cAMP inhibits growth and induces differentiation and apoptosis in retinoblastoma cells. Int J Cancer. 1997;72:1088-1094.
51. Cox GA, Sunada Y, Campbell KP, Chamberlain J. SDp71 can restore the dystrophin-associated glycoprotein complex in muscle hut fails to prevent dystrophy. Nat Genet. 1994;8:333-339.
52. Greenberg DS, Sunada Y, Campbell KP, Yaffe D, Nudel U. Exogenous Dp71 restores the levels of dystrophin associated proteins but does not alleviate muscle damage in mdx mice. Nat Genet. 1994;8:340-344.
53. Kramarcy NR, Vidal A, Froehner SC, Sealock R. Association of utrophin and multiple dystrophin short forms with the mammalian M(r) 58,000 dystrophin-associated protein (syntrophin). J Biol Chem. 1994;269:2870-2876.
54. Khurana TS, Watkins SC, Kunkel LM. The subcellular distribution of chromosome 6-encoded dystrophin-related protein in the brain. J Cell Biol. 1992;119:357-366.
55. Ueda H, Tsukahara S, Kobayashi K, Ohno S. Immunochemichal study of dystrophin-related protein in the rat retina. Ophthalmic Res. 1995;27:219-226.
56. Araki E, Nakamura K, Nakao K, et al. Targeted disruption of exon 52 in the mouse dystrophin gene induced muscle degeneration similar to that observed in Duchenne muscular dystrophy. Biochem Biophys Res Commun. 1997;238:492-497.
57. Blank M, Koulen P, Kröger S. Subcellular concentration of beta-dystroglycan in photoreceptors and glial cells of the chick retina. J Comp Neurol. 1997;389:668-678.
58. Ueda H. Gohdo T, Ohno S. Beta-dystroglycan localization in the photoreceptor and Muller cells in the rat retina revealed by immunoelectron microscopy. J Histochem Cytochem. 1998;46:185-191.
59. Koulen P, Blank M, Kroger S. Differential distribution of beta-dystroglycan in rabbit and rat retina. J Neurosci Res. 1998;51:735-747.
60. Roberts RG, Barby TF, Manners E, Bobrow M, Bentley DR. Direct detection of dystrophin gene rearrangements by analysis of dystrophin mRNA in peripheral blood lymphocytes. Am J Hum Genet. 1991;49:298-310.
61. Roberts RG, Coffey AJ, Bobrow M, Bentley DR. Determination of the exon structure of the distal portion of the dystrophin gene by vectorette PCR. Genomics 1992;13:942-950.