The heterogeneity of the osteoblast phenotype

Endocrinologist

Volumn 9, Issue 1, 1999, Pages 25-31

  Aubin, Jane E ^a,b   Antonio Candeliere, G ^a   Bonnelye, Edith ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; BONE MATRIX; CELL SUBPOPULATION; GENE EXPRESSION REGULATION; GENETIC HETEROGENEITY; NONHUMAN; OSTEOBLAST; PHENOTYPE; PREDICTION; RAT; REGULATORY MECHANISM; REVIEW;

EID: 0033050362     PISSN: 10512144     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019616-199901000-00006     Document Type: Review

References (20)

1. Rodan GA, Heath JK, Yoon K, Noda M, Rodan SB: Diversity of the osteoblastic phenotype. Ciba Found Symp 1988; 136: 78-91.
2. Aubin JE, Turksen K, Heersche JNM: Osteoblastic cell lineage. In Cellular and Molecular Biology of Bone, edited by Noda M, pp. M5, Toronto, Academic Press, 1993.
3. Aubin JE, Liu F: The osteoblast lineage. In Principles of Bone Biology, edited by Bilezikian JP, Raisz LG, Rodan GA, pp. 51-67, Toronto, Academic Press, 1996.
4. Stein OS, Lian JB, Stein JL, van Wijnen AJ, Frenkel B, Montecino M: Mechanisms regulating osteoblast proliferation and differentiation. In Principles of Bone Biology, edited by Bilezikian JP, Raisz LG, Rodan GA, pp. 69-86, Toronto, Academic Press, 1996.
5. Malaval L, Modrowski D, Gupta AK, Aubin JE: Cellular expression of bone-related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures. J Cell Physiol 1994; 158: 555-72.
6. Liu F, Malaval L, Gupta AK, Aubin JE: Simultaneous detection of multiple bone-related mRNAs and protein expression during osteoblast differentiation: polymerase chain reaction and immunocytochemical studies at the single cell level. Dev Biol 1994; 166: 220-34.
7. Pockwinse SM, Stein JL, Lian JB, Stein GS: Developmental stagespecific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization. Exp Cell Res 1995; 216: 244-60.
8. Liu F, Malaval L, Aubin JE: The mature osteoblast phenotype is characterized by extensive plasticity. Exp Cell Res 1997; 232: 97-105.
9. Chen J, Singh K, Mukherjee BB, Sodek J: Developmental expression of osteopontin (OPN) mRNA in rat tissues: evidence for a role for osteopontin in bone formation and resorption. Matrix 1993; 13: 113-23.
10. Heersche JNM, Reimers SM, Wrana JL, Waye MM, Gupta AK: Changes in expression of alpha 1 type 1 collagen and osteocalcin mRNA in osteoblasts and odontoblasts at different stages of maturity as shown by in situ hybridization. Proc Finn Dent Soc 1992; 88 (Suppl 1): 173-82.
11. Bianco P, Riminucci M, Bonucci E, Termine JD, Robey PG: Bone sialoprotein (BSP) secretion and osteoblast differentiation: relationship to bromodeoxyuridine incorporation, alkaline phosphatase, and matrix deposition. J Histochem Cytochem 1993; 41:183-91.
12. Ikeda T, Nomura S, Yamaguchi A, Suda T, Yoshiki S: In situ hybridization of bone matrix proteins in undecalcified adult rat bone sections. J Histochem Cytochem 1992; 40: 1079-88.
13. Candeliere GA, Liu F, Aubin JE: Heterogeneity of marker expression by osteoblasts in different developmental zones of bone in the 21d fetal rat calvaria. J Bone Miner Res 1997; 12(Suppl. 1):S187.
14. Ninomiya JT, Tracy RP, Galore JD, Gendreau MA, Keim RJ, Mann KG: Heterogeneity of human bone. J Bone Miner Res 1990; 5: 933-8.
15. Ingram RT, Clarke BL, Fisher LW, Fitzpatrick LA: Distribution of noncollagenous proteins in the matrix of adult human bone: evidence of anatomic and functional heterogeneity. J Bone Miner Res 1993; 8: 1019-29.
16. Amling M, Herden S, Posl M, Hahn M, Ritzel H, Delling G: Heterogeneity of the skeleton: comparison of the trabecular microarchitecture of the spine, the iliac crest, the femur, and the calcaneus. J Bone Mine Res 1996; 11:36-45.
17. Ducy P, Desbois C, Boyce B, et al.: Increased bone formation in osteocalcin-deficient mice. Nature 1996; 382: 448-52.
18. Jemtland R, Lee K, Segre GV: Heterogeneity among cells that express osteoclast-associated genes in developing bone. Endocrinology 1998; 139: 340-9.
19. Onoe Y, Miyaura C, Ohta H, Nozawa S, Suda T: Expression of estrogen receptor β in rat bone. Endocrinology 1997; 138: 4509-12.
20. Ikeda T, Nagai Y, Yamaguchi A, Yokose S, Yoshiki S: Age-related reduction in bone matrix protein mRNA expression in rat bone tissues: application of histomorphometry to in situ hybridization. Bone 1995; 16: 17-23.