Melanoma antigen-encoding gene expression in melanocytic naevi and cutaneous malignant melanomas

British Journal of Dermatology

Volumn 140, Issue 1, 1999, Pages 106-108

  Basarab, T ^a   Picard, J K ^a   Simpson, E ^a   Russell Jones, R ^b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Cutaneous malignant melanoma; Melanocytic naevi; Melanoma antigen encoding genes; Reverse transcription polymerase chain reaction

Indexed keywords

COMPLEMENTARY DNA; HLA ANTIGEN; MELANOMA ANTIGEN;

ANTIGEN RECOGNITION; ARTICLE; CANCER CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; DYSPLASTIC NEVUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MELANOCYTIC NEVUS; MELANOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTIGENS, NEOPLASM; BIOPSY; GENE EXPRESSION; HUMANS; MELANOMA; NEOPLASM PROTEINS; NEVUS, PIGMENTED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN NEOPLASMS;

EID: 0033050053     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1999.02616.x     Document Type: Article

References (12)

1. van der Bruggen P, Traversari C, Chomez P et al. A gene encoding an antigen recognised by cytolytic T lymphocytes on a human melanoma. Science 1991; 254: 1643-7.
2. Traversari C, van der Bruggen P, Luescher IF et al. A nonapeptide encoded by human gene MAGE-1 is recognised on HLA-A1 by cytolytic T lymphocytes directed against tumour antigen MZ2-E. J Exp Med 1992; 176: 1453-7.
3. De Plaen E, Arden K, Traversari C et al. Struture, chromosomal localization and expression of twelve genes of the MAGE family. Immunogenetics 1994; 40: 160-9.
4. De Smet C, Lurquin C, van der Bruggen P et al. Sequence and expression pattern of human MAGE-2 gene. Immunogenetics 1994; 39: 121-9.
5. Becker JC, Gillitzer R, Brocker EB. A member of the melanoma antigen-encoding gene (MAGE) family is expressed in human skin during wound healing. Int J Cancer 1994; 58: 346-8.
6. Brasseur F, Rimold D, Lienard D et al. Expression of MAGE genes in primary and metastatic cutaneous melanoma. Int J Cancer 1995; 63: 375-80.
7. Weber J, Salgaller M, Samid D et al. Expression of the MAGE-1 tumour antigen is up-regulated by the demethylating agent 5-aza-2′-deoxycytidine. Cancer Res 1994; 54: 1766-71.
8. Hofbauer GF, Schaefer C, Noppen C et al. MAGE-3 immunoreactivity in formalin-fixed, paraffin-embedded primary and metastatic melanoma: Frequency and distribution. Am J Pathol 1997; 151: 1549-53.
9. Hoon DS, Yuzuki D, Hayashida M, Morton DL. Melanoma patients immunized with melanoma cell vaccine induce antibody responses to recombinant MAGE-1 antigen. J Immunol 1995; 154: 730-7.
10. Itoh K, Hayashi A, Nakao M et al. Human tumour rejection antigens MAGE. J Biochem 1996; 119: 385-90.
11. Zakut R, Topalian SL, Kawakami Y et al. Differential expression of MAGE-1 -2, and -3 in messenger RNA in transformed and normal human cell lines. Cancer Res 1993; 53: 5-8.
12. De Smet C, De Backer O, Faraoni J et al. The activation of human gene MAGE-1 in tumour cells is correlated with genome-wide demethylation. Proc Natl Acad Sci USA 1996; 93: 7149-53.