Density predicts the activity-dependent failure load of proximal femora with defects

Skeletal Radiology

Volumn 28, Issue 2, 1999, Pages 90-95

  Michaeli, D A ^a   Inoue, K ^a   Hayes, W C ^a   Hipp, J A ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Biomechanics; Bone; Cadaver; DXA; Fracture; Metastases

Indexed keywords

ADULT; AGED; ARTICLE; BONE DENSITY; BONE METASTASIS; BONE MINERAL; CADAVER; CLINICAL ARTICLE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; HUMAN; HUMAN TISSUE; MALE; MEASUREMENT; PRIORITY JOURNAL; SIMULATION;

AGED; AGED, 80 AND OVER; BONE DENSITY; BONE NEOPLASMS; CADAVER; DENSITOMETRY, X-RAY; FEMALE; FEMORAL FRACTURES; FEMUR; FRACTURES, SPONTANEOUS; HUMANS; MALE; MIDDLE AGED; MODELS, ANATOMIC; PREDICTIVE VALUE OF TESTS; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT-BEARING;

EID: 0033049967     PISSN: 03642348     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002560050480     Document Type: Article

References (34)

1. Tubiana-Hulin M. Incidence, prevalence and distribution of bone metastases. Bone 1991; 12:S9-S10.
2. Wingo PA, Tong T, Bolden S. Cancer statistics, 1995. CA Cancer J Clin 1995; 45:127-128.
3. Coleman RE, Rubens RD. The clinical course of bone metastases from breast cancer. Br J Cancer 1987; 55:61-66.
4. Harrington KD. New trends in the management of lower extremity metastases. Clin Orthop 1982; 169:53-61.
5. Menck H, Schulze S, Larsen E. Metastasis size in pathologic femoral fractures. Acta Orthop Scand 1988; 59: 151-154.
6. Mirels H. Metastatic disease in long bones. Clin Orthop 1989; 249: 256-264.
7. Thompson R. Impending fracture associated with bone destruction. Orthopedics 1992; 15:547-550.
8. Hipp JA, Springfield D, Hayes W. Predicting pathologic fracture risk in the management of metastatic bone defects. Clin Orthop 1995; 312: 120-135.
9. Keene JS, Sellinger DS, McBeath AA, Engber WD. Metastatic breast cancer in the femur: a search for the lesion at risk of fracture. Clin Orthop 1986; 203:282-288.
10. Cummings S, Black D, Nevitt M, et al. Bone density at various sites for prediction of hip fractures. Lancet 1993; 341: 72-89.
11. Hui SL, Slemenda CW, Carey MA, Johnston CC. Choosing between predictors of fractures. J Bone Miner Res 1995; 10: 1816-1822.
12. Alho A, Husby T, Hoiseth A. Bone mineral content and mechanical strength. an ex-vivo study of human femora at autopsy. Clin Orthop 1988; 227: 292-297.
13. Courtney A, Wachtel E, Myers E, Hayes W. Effects of loading rate on strength of the proximal femur. Calcif Tissue Int 1994; 55: 53-58.
14. Courtney A, Wachtel E, Myers E, Hayes W. Age-related reductions in the strength of the femur tested in a fall-loading configuration. J Bone Joint Surg Am 1995; 77:387-395.
15. Dalen N, Hellstrom LG, Jacobson B. Bone mineral content and mechanical strength of the femoral neck. Acta Orthop Scand 1976; 47: 503-508.
16. Leichter I, Margulies JY, Weinreb A, et al. The relationship between bone density, mineral content, and mechanical strength in the femoral neck. Clin Orthop 1982; 163: 272-281.
17. Sartoris DJ, Sommer FG, Kosek J, Gies A, Carter D. Dual-energy projection radiography in the evaluation of femoral neck strength, density, and mineralization. Invest Radiol 1985; 20: 476-485.
18. Webber CE. The effect of fat on bone mineral measurements in normal subjects with recommended values of bone, muscle and fat attenuation coefficients. Clin Physiol Meas 1987; 8: 143-158.
19. Cheal E, Spector M, Hayes W. Role of loads and prosthesis material properties on the mechanics of the proximal femur after total hip arthroplasty. J Orthop Res 1992; 10:405-422.
20. Fuleihan GE, Testa MA, Angell JE, Porrino N, Leboff MS. Reproducibility of DXA absorptiometry: a model for bone loss estimates. J Bone Miner Res 1995; 10: 1004-1014.
21. Zar J. Biostatistical analysis, 2nd edn. Englewood Cliffs, NJ: Prentice Hall, 1984.
22. Genant H, Grampp S, Gluer C, et al. Universal stabilization for dual x-ray absorptiometry: patient and phantom cross-calibration results. J Bone Miner Res 1994; 9: 1503-1514.
23. Mizrahi J, Margulies JY, Leichter I, Deutsch D. Fracture of the human femoral neck: effect of density of the cancellous core. J Biomed Eng 1984; 6: 56-62.
24. McBroom RJ, Cheal EJ, Hayes WC. Strength reductions from metastatic cortical defects in long bones. J Orthop Res 1988; 6: 369-378.
25. Hipp JA, Rosenberg AE, Hayes WC. Mechanical properties of trabecular bone within and adjacent to osseous metastases. J Bone Miner Res 1992; 7: 1165-1171.
26. Cheal E, Hipp J, Hayes W. Evaluation of finite element analysis for prediction of the strength reduction due to metastatic lesions in the femoral neck. J Biomech 1993; 26: 251-264.
27. Hipp JA, Edgerton BC, An KN, Hayes WC. Structural consequences of transcortical holes in long bones loaded in torsion. J Biomech 1990; 23: 1261-1268.
28. Hipp JA, Katz G, Hayes WC. Local demineralization as a model for bone strength reductions in lytic transcortical metastatic lesions. Invest Radiol 1991: 26: 934-938.
29. Hipp JA, McBroom RJ, Cheal EJ, Hayes WC. Structural consequences of endosteal metastatic lesions in long bones. J Orthop Res 1989; 7: 828-837.
30. Hayes WC, Myers ER, Morris JN, et al. Impact near the hip dominates fracture risk in elderly nursing home residents who fall. Calcif Tissue Int 1993; 52: 192-198.
31. Myers ER, Hayes WC. Age-related hip fractures. Curr Opinion in Orthop 1994; 5: 9-15.
32. Bergmann G, Grichen F. Rohlmann A. Hip joint loading during walking and running measured in two patients. J Biomech 1993; 25: 969-990.
33. Kotzar GM, Davy DT, Goldberg VM, et al. Telemeterized in vivo hip joint force data: a report on two patients after total hip surgery. J Orthop Res 1991; 9: 621-623.
34. Rushefeldt PD. Mann RW. Improved techniques for measuring in vitro the geometry and pressure distribution in the human acetabulum. II. Instrumented endoprosthesis measurement of articular surface pressure distribution. J Biomech 1981; 14: 315-323.