Low neutral endopeptidase levels in bronchoalveolar lavage fluid of lung cancer patients

American Journal of Respiratory and Critical Care Medicine

Volumn 159, Issue 3, 1999, Pages 907-910

  Cohen, Andrea J ^a,b   Franklin, Wilbur A ^a,b   Magill, Cathy ^a,b   Sorenson, Julie ^a,b   Miller, York E ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b Arris Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE METALLOENDOPEPTIDASE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GROWTH INHIBITION; HUMAN; LUNG CANCER; LUNG LAVAGE; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0033049826     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.159.3.9806062     Document Type: Article

References (35)

1. 1. Shipp, M. A., N. E. Richardson, P. H. Sayre, N. R. Brown, E. L. Masteller, L. K. Clayton, J. Ritz, and E. L. Reinherz. 1988. Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein. Proc. Natl. Acad. Sci. U.S.A. 85:4819-4823.
2. 2. LeBien, T. W. and R. T. McCormack. 1989. The common acute lymphoblastic leukemia antigen (CD-10): emancipation from a functional enigma. Blood 73:625-635.
3. 3. D'Adamio, L., M. A. Shipp, E. L. Masteller, and E. L. Reinherz. 1989. Organization of the gene encoding common acute lymphoblastic leukemia antigen (neutral endopeptidase 24.11): multiple miniexons and separate 5′ untranslated regions. Proc. Natl. Acad. Sci. U.S.A. 86: 7103-7107.
4. 4. Shipp, M. A., and A. T. Look. 1993. Hematopoietic differentiation antigens that are membrane associated enzymes: cutting is the key! Blood 82:1052-1070.
5. 5. Shipp, M. A., J. Vijayaraghavan, E. F. Schmidt, E. L. Masteller, L. D'Adamio, L. B. Hersh, and E. L. Reinherz. 1989. Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis. Proc. Natl. Acad. Sci. U.S.A. 86:297-301.
6. 6. Shipp, M. A., G. E. Tarr, C. Y. Chen, S. N. Switzer, L. B. Hersh, H. Stein, M. E. Sunday, and E. L. Reinherz. 1991. CD10 neutral endopeptidase 24.11 hydrolyses bombesin-like peptides and regulates the growth of small cell carcinomas of the lung. Proc. Natl. Acad. Sci. U.S.A. 88:10662-10666.
7. 7. King, K. A., J. Hua, J. S. Torday, J. M. Drazen, S. A. Graham, M. A. Shipp, and M. E. Sunday. 1993. CD10/Neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides. J. Clin. Invest. 91:1969-1973.
8. 8. Sunday, M. E., J. Hua, J. S. Torday, B. Reyes, and M. A. Shipp. 1992. CD10/neutral endopeptidase in developing human fetal lung: patterns of expression and modulation of peptide-mediated proliferation. J. Clin. Invest. 90:2517-2525.
9. 9. Stimler-Gerard, N. P. 1987. Neutral endopeptidase-like enzyme controls the contractile activity of substance P in guinea pig lung. J. Clin Invest. 79:1819-1825.
10. 10. Martins, M. A., S. A. Shore, N. P. Gerard, C. Gerard, and J. M. Drazen. 1990. Peptidase modulation of pulmonary effects of tachykinins in tracheal superperfused guinea pig lungs. J. Clin. Invest. 85:170-176.
11. 11. Shipp, M. A., G. B. Stefano, S. N. Switzer, J. D. Griffin, and E. L. Reinherz. 1991. CD10 (CALLA) neutral endopeptidase 24.11 modulates inflammatory peptide-induced changes in neutrophil morphology: migration, and adhesion proteins and is itself regulated by neutrophil activation. Blood 78:1834-1841.
12. 12. Nadel, J. A. 1990. Decreased neutral endopeptidase: possible role in inflammatory disease of airways. Lung (Suppl.) 168:123-127.
13. 13. Erdos, E. G., B. Wagner, C. B. Harbury, R. G. Painter, R. A. Skidgel, and X. G. Fa. 1989. Down-regulation and inactivation of neutral endopeptidase 24.11 (enkephalinase) in human neutrophils. J. Biol. Chem. 264:1419-1423.
14. 14. Lu, B., N. P. Gerard, L. F. Kolakowski, Jr., O. Finco, M. C. Carroll, and C. Gerard. 1996. Neutral endopeptidase modulates septic shock. Ann. N.Y. Acad. Sci. 780:156-163.
15. 15. Lu, B., M. Figini, C. Emanueli, P. Geppetti, E. F. Grady, N. P. Gerard, J. Anselli, D. G. Payan, C. Gerard, and N. Bunnett. 1997. The control of microvascular permeability and blood pressure by neutral endopeptidase. Nature Med. 3:904-907.
16. 16. Cohen, A. J., P. A. Bunn, W. Franklin, C. Magill-Solc, C. Hartmann, B. Helfrich, L. Gilman, J. Folkvord, K. Helm, and Y. E. Miller. 1996. Neutral endopeptidase: variable expression in human lung, inactivation in lung cancer, and modulation of peptide induced calcium flux. Cancer Res. 56:831-839.
17. 17. Ganju, R. K., M. Sunday, D. G. Twarwhas, A. Card, and M. A. Shipp. 1994. CD10/NEP in non small cell lung carcinomas: relationship to cellular proliferation. J. Clin. Invest. 94:1784-1791.
18. 18. Bunn, P. A., D. Brenner, D. Chan, B. Helfrich, A. J. Cohen, and Y. E. Miller. 1998. Effects of recombinant neutral endopeptidase on human lung cancer cell lines. Clin. Cancer Res. 4:2849-2858.
19. 19. Cohen, A. J., T. E. King, Jr., L. B. Gilman, C. Magill-Solc, and Y. E. Miller. 1998. Neutral endopeptidase: High expression in idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells. Am. J. Respir. Crit. Care Med. 158:1593-1599.
20. 20. Cohen, A. J., T. E. King, Jr., C. Magill-Solc, C. Hartmann, and Y. E. Miller. 1995. Neutral endopeptidase expression is high in respiratory bronchiolitis-interstitial lung disease (abstract). Am. J. Respir. Cell Mol. Biol. 151:A52.
21. 21. Cohen, A. J., T. E. King, Jr., W. A. Franklin, and Y. E. Miller. 1994. Neutral endopeptidase expression in eosinophilic granuloma. Am. J. Respir. Crit. Care. Med. 17:B123.
22. 22. Cuttitta, R., D. N. Carney, J. Mulshine, T. W. Moody, J. Fedorko, A. Fischler, and J. D. Minna. 1985. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature (Lond.) 316:823-826.
23. 23. Siegfried, J. M., Y. H. Hah, M. A. DeMichele, J. D. Hunt, A. L. Gaither, and F. Cuttitta. 1994. Production of gastrin-releasing peptide by a non-small cell lung carcinoma cell line adapted to serum-free and growth factor-free conditions. J. Biol. Chem. 269:8596-8603.
24. 24. Aguayo, S. M., T. E. King, Jr., J. A. Waldron, K. M. Sherritt, M. A. Kane, and Y. E. Miller. 1990. Increased pulmonary neuroendocrine cells with bombesin-like immunoreactivity in adult patients with eosinophilic granuloma. J. Clin. Invest. 86:838-844.
25. 25. Siegfried, J. M., P. J. Guentert, and A. L. Gaither. 1993. Effects of bombesin and gastrin-releasing peptide on human bronchial epithelial cells from a series of donors: individual variation and modulation by bombesin analogues. Anat. Rec. 236:241-247.
26. 26. Willey, J. C., J. F. Lechner, and C. C. Harris. 1984. Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells. Exp. Cell Res. 153: 245-248.
27. 27. Cohen, A. J., T. E. King, S. A. Aguayo, and Y. E. Miller. 1995. Bombesin immunoreactive neuroendocrine cells are increased in respiratory bronchiolitis-interstitial lung disease. Am. J. Respir. Crit. Care Med. 151:52.
28. 28. Aguayo, S. M., M. A. Kane, T. E. King, Jr., M. I. Schwarz, L. Grauer, and Y. E. Miller. 1989. Increased levels of bombesin-like peptides in the lower respiratory tract of asymptomatic cigarette smokers. J. Clin. Invest. 84:1105-1113.
29. 29. Aguayo, S. M., T. E. King, Jr., M. A. Kane, K. M. Sherritt, W. Silvers, L. M. Nett, T. L. Petty, and Y. E. Miller. 1992. Urinary levels of bombesin-like peptides in asymptomatic cigarette smokers: a potential risk marker for smoking related diseases. Cancer Res. (Suppl.) 52:2727s-2731s.
30. 30. Miller, Y. E., C. H. Welsh, A. Prochazka, and S. M. Aguayo. 1994. Bombesin-like peptides in pulmonary disease and lung cancer. Lung Cancer 11:211.
31. 31. Watters, L. C., M. I. Schwarz, R. M. Cherniak, J. A. Waldron, T. L. Dunn, R. E. Stanford, and T. E. King. 1987. Idiopathic pulmonary fibrosis: pretreatment bronchoalveolar lavage cellular constituents and their relationships with lung histopathology and clinical response to therapy. Am. Rev. Respir. Dis. 135: 696-704.
32. 32. Dusser, D. J., T. D. Djokic, D. B. Borson, and J. A. Nadel. 1989. Cigarette smoke induces bronchoconstrictor hyperresponsiveness to substance P and inactivates airway neutral endopeptidase in the guinea pig. Possible role of free radicals. J. Clin. Invest. 84:900-906.
33. 33. Roisman, G. L., N. Lacronique, N. De Smazes-Dufeu, and D. J. Dusser. 1995. Neutral endopeptidase and kinase II activities in the bronchial mucosa of smoking and nonsmoking subjects (abstract). Am. J. Respir. Crit. Care Med. 151:A97.
34. 34. Siegfried, J. M., M. A. DeMichele, J. D. Hunt, A. G. Davis, K. P. Vohra, and J. M. Pilewski. 1997. Expression of mRNA for gastrin-releasing peptide receptor by human bronchial epithelial cells. Association with prolonged tobacco exposure and responsiveness to bombesin-like peptides. Am. J. Respir. Crit. Care Med. 156:358-366.
35. 35. Cambien, F., O. Poirier, L. Lecerf, A. Evans, J. P. Cambou, D. Arveiler, G. Luc, J. M. Bard, L. Bara, and S. Richards. 1992. Deletion polymorphism in the gene for angiotensin-coverting enzyme is a potent risk factor for myocardial infarction. Nature 359:641-644.