메뉴 건너뛰기




Volumn 55, Issue 2, 1999, Pages 348-355

A structure-based approach to nicotinic receptor pharmacology

Author keywords

[No Author keywords available]

Indexed keywords

CINCHOCAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; NICOTINIC RECEPTOR; PRILOCAINE; TETRACAINE;

EID: 0033049566     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.55.2.348     Document Type: Article
Times cited : (26)

References (29)
  • 1
    • 0029922297 scopus 로고    scopus 로고
    • Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor
    • Arias HR (1996) Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor. Mol Membr Biol 13:1-17.
    • (1996) Mol Membr Biol , vol.13 , pp. 1-17
    • Arias, H.R.1
  • 2
    • 0028246033 scopus 로고
    • Ligand-receptor interactions in the nicotinic acetylcholine receptor probed using multiple substitutions at conserved tyrosines on the alpha subunit
    • Aylwin ML and White MM (1994) Ligand-receptor interactions in the nicotinic acetylcholine receptor probed using multiple substitutions at conserved tyrosines on the alpha subunit. FEBS Lett 349:99-103.
    • (1994) FEBS Lett , vol.349 , pp. 99-103
    • Aylwin, M.L.1    White, M.M.2
  • 3
    • 0030894826 scopus 로고    scopus 로고
    • Desensitization of the nicotinic acetylcholine receptor mainly involves a structural change in the solvent-accessible regions of the polypeptide backbone
    • Baenziger JE and Chew JP (1997) Desensitization of the nicotinic acetylcholine receptor mainly involves a structural change in the solvent-accessible regions of the polypeptide backbone. Biochemistry 36:3617-3624.
    • (1997) Biochemistry , vol.36 , pp. 3617-3624
    • Baenziger, J.E.1    Chew, J.P.2
  • 4
    • 0026577319 scopus 로고
    • Incorporation of the nicotinic acetylcholine receptor into biologically active planar multilamellar films: Characterization by fluorescence and FTIR difference spectroscopy
    • Baenziger JE, Miller KW and Rothschild KJ (1992) Incorporation of the nicotinic acetylcholine receptor into biologically active planar multilamellar films: Characterization by fluorescence and FTIR difference spectroscopy. Biophys J 61:983-999.
    • (1992) Biophys J , vol.61 , pp. 983-999
    • Baenziger, J.E.1    Miller, K.W.2    Rothschild, K.J.3
  • 5
    • 0027190929 scopus 로고
    • Fourier transform infrared difference spectroscopy of the nicotinic acetylcholine receptor: Evidence for specific protein structural changes upon desensitization
    • Baenziger JE, Miller KW and Rothschild KJ (1993) Fourier transform infrared difference spectroscopy of the nicotinic acetylcholine receptor: Evidence for specific protein structural changes upon desensitization. Biochemistry 32:5448-5454.
    • (1993) Biochemistry , vol.32 , pp. 5448-5454
    • Baenziger, J.E.1    Miller, K.W.2    Rothschild, K.J.3
  • 6
    • 0018573151 scopus 로고
    • Interaction of local anesthetics with Torpedo californica membrane-bound acetylcholine receptor
    • Blanchard SG, Elliot J and Raferty MA (1979) Interaction of local anesthetics with Torpedo californica membrane-bound acetylcholine receptor. Biochemistry 18: 5880-5885.
    • (1979) Biochemistry , vol.18 , pp. 5880-5885
    • Blanchard, S.G.1    Elliot, J.2    Raferty, M.A.3
  • 7
    • 0023776215 scopus 로고
    • Fourier transform infrared techniques for probing membrane protein structure
    • Braiman MS and Rothschild KJ (1988) Fourier transform infrared techniques for probing membrane protein structure. Annu Rev Biophys Chem 17:541-570.
    • (1988) Annu Rev Biophys Chem , vol.17 , pp. 541-570
    • Braiman, M.S.1    Rothschild, K.J.2
  • 8
    • 0019225785 scopus 로고
    • 3H]carbamylcholine to Torpedo postsynaptic membranes: Slow conformational transitions of the cholinergic receptor
    • 3H]carbamylcholine to Torpedo postsynaptic membranes: Slow conformational transitions of the cholinergic receptor. Biochemistry 19:5344-0353.
    • (1980) Biochemistry , vol.19 , pp. 5344-10353
    • Boyd, N.D.1    Cohen, J.B.2
  • 9
    • 0019225784 scopus 로고
    • 3H] acetylcholine to Torpedo postsynaptic membranes: Association and dissociation rate constants by rapid mixing and ultrafiltration
    • 3H] acetylcholine to Torpedo postsynaptic membranes: Association and dissociation rate constants by rapid mixing and ultrafiltration. Biochemistry 19:5353-5358.
    • (1980) Biochemistry , vol.19 , pp. 5353-5358
    • Boyd, N.D.1    Cohen, J.B.2
  • 12
    • 0026344986 scopus 로고
    • 3H]Acetylcholine mustard identifies residues in the cation-binding subsite
    • 3H]Acetylcholine mustard identifies residues in the cation-binding subsite. J Biol Chem 266:23354-23364.
    • (1991) J Biol Chem , vol.266 , pp. 23354-23364
    • Cohen, J.B.1    Sharp, S.D.2    Liu, W.S.3
  • 13
    • 0016246242 scopus 로고
    • Effects of local anesthetics and calcium on the interaction of cholinergic ligands with the nicotinic receptor protein from Torpedo marmorata
    • Cohen JB, Weber M and Changeux J-P (1974) Effects of local anesthetics and calcium on the interaction of cholinergic ligands with the nicotinic receptor protein from Torpedo marmorata. Mol Pharmacol 10:904-932.
    • (1974) Mol Pharmacol , vol.10 , pp. 904-932
    • Cohen, J.B.1    Weber, M.2    Changeux, J.-P.3
  • 14
  • 15
    • 0025675821 scopus 로고
    • Acetylcholine binding by a synthetic receptor: Implications for biological recognition
    • Dougherty DA and Stauffer DA (1990) Acetylcholine binding by a synthetic receptor: Implications for biological recognition. Science (Wash DC) 250:1558-1560.
    • (1990) Science (Wash DC) , vol.250 , pp. 1558-1560
    • Dougherty, D.A.1    Stauffer, D.A.2
  • 16
    • 0028848223 scopus 로고
    • A discrete site for general anesthetics on a postsynaptic receptor
    • Forman SA, Miller KW and Yellen G (1995) A discrete site for general anesthetics on a postsynaptic receptor. Mol Pharmacol 48:574-581.
    • (1995) Mol Pharmacol , vol.48 , pp. 574-581
    • Forman, S.A.1    Miller, K.W.2    Yellen, G.3
  • 17
    • 0025884565 scopus 로고
    • Functional architecture of the nicotinic acetylcholine receptor: From electric organ to brain
    • Galzi J-L, Revah F, Bessis A and Changeux J-P (1991) Functional architecture of the nicotinic acetylcholine receptor: From electric organ to brain. Annu Rev Pharmacol 31:37-72.
    • (1991) Annu Rev Pharmacol , vol.31 , pp. 37-72
    • Galzi, J.-L.1    Revah, F.2    Bessis, A.3    Changeux, J.-P.4
  • 18
    • 0018790793 scopus 로고
    • Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata
    • Heichnann T and Changeux J-P (1979a) Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata. Eur J Biochem 94:255-279.
    • (1979) Eur J Biochem , vol.94 , pp. 255-279
    • Heichnann, T.1    Changeux, J.-P.2
  • 19
    • 0018762233 scopus 로고
    • Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites
    • Heidmann T and Changeux J-P (1979b) Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites. Eur J Biochem 94:281-296.
    • (1979) Eur J Biochem , vol.94 , pp. 281-296
    • Heidmann, T.1    Changeux, J.-P.2
  • 20
    • 0020621092 scopus 로고
    • Multiple sites of action for non-competitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata
    • Heidmann T, Oswald RE and Changeux JP (1983) Multiple sites of action for non-competitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata. Biochemistry 22:3112-3127.
    • (1983) Biochemistry , vol.22 , pp. 3112-3127
    • Heidmann, T.1    Oswald, R.E.2    Changeux, J.P.3
  • 21
    • 0018351106 scopus 로고
    • Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue
    • Krodel EK, Beckman RA and Cohen JB (1979) Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue. Mol Pharmacol 15:294-312.
    • (1979) Mol Pharmacol , vol.15 , pp. 294-312
    • Krodel, E.K.1    Beckman, R.A.2    Cohen, J.B.3
  • 22
    • 0026699633 scopus 로고
    • Effects of lipids and detergents on the conformation of the nicotinic acetylcholine receptor from Torpedo californica
    • McCarthy MP and Moore MA (1992) Effects of lipids and detergents on the conformation of the nicotinic acetylcholine receptor from Torpedo californica. J Biol Chem 267:7655-7663.
    • (1992) J Biol Chem , vol.267 , pp. 7655-7663
    • McCarthy, M.P.1    Moore, M.A.2
  • 24
    • 0029768099 scopus 로고    scopus 로고
    • Structural effects of neutral and anionic lipids on the nicotinic acetylcholine receptor
    • Ryan SE, Demers CN, Chew JP and Baenziger JE (1996) Structural effects of neutral and anionic lipids on the nicotinic acetylcholine receptor. J Biol Chem 271:24590-24597.
    • (1996) J Biol Chem , vol.271 , pp. 24590-24597
    • Ryan, S.E.1    Demers, C.N.2    Chew, J.P.3    Baenziger, J.E.4
  • 25
    • 0028292368 scopus 로고
    • Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists
    • Sine SM, Quiram P, Papanikolaou F, Kreienkamp HJ and Taylor P (1994) Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists. J Biol Chem 269:8808-8816.
    • (1994) J Biol Chem , vol.269 , pp. 8808-8816
    • Sine, S.M.1    Quiram, P.2    Papanikolaou, F.3    Kreienkamp, H.J.4    Taylor, P.5
  • 26
    • 0025697223 scopus 로고
    • Nicotinic acetylcholine receptor superfamily of ligand-gated ion channels
    • Stroud RM, McCarthy MP and Shuster M (1990) Nicotinic acetylcholine receptor superfamily of ligand-gated ion channels. Biochemistry 29:11009-11023.
    • (1990) Biochemistry , vol.29 , pp. 11009-11023
    • Stroud, R.M.1    McCarthy, M.P.2    Shuster, M.3
  • 27
    • 0026004411 scopus 로고
    • Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor
    • Tomaselli GF, McLaughlin JT, Jurman ME, Hawrot E and Yellen G (1991) Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor. Biophys J 60:721-727.
    • (1991) Biophys J , vol.60 , pp. 721-727
    • Tomaselli, G.F.1    McLaughlin, J.T.2    Jurman, M.E.3    Hawrot, E.4    Yellen, G.5
  • 28
    • 0015980334 scopus 로고
    • 3H]∀-toxin to membrane fragments from Electrophorus and Torpedo electric organs
    • 3H]∀-toxin to membrane fragments from Electrophorus and Torpedo electric organs. Mol Pharmacol 10:35-40.
    • (1974) Mol Pharmacol , vol.10 , pp. 35-40
    • Weber, M.1    Changeux, J.-P.2
  • 29
    • 0017717088 scopus 로고
    • Kinetics of agonist-mediated transitions in state of the cholinergic receptor
    • Weiland G, Georgia B, Lappi S, Chignell CF and Taylor P (1977) Kinetics of agonist-mediated transitions in state of the cholinergic receptor. J Biol Chem 252:7648-7656.
    • (1977) J Biol Chem , vol.252 , pp. 7648-7656
    • Weiland, G.1    Georgia, B.2    Lappi, S.3    Chignell, C.F.4    Taylor, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.