Bioaccumulation of 2,4,6-trinitrotoluene and polychlorinated biphenyls through two routes of exposure in a terrestrial amphibian: Is the dermal route significant?

Environmental Toxicology and Chemistry

Volumn 18, Issue 5, 1999, Pages 873-878

  Johnson, Mark S ^a,d   Franke, Laura S ^a   Lee, Robyn B ^b   Holladay, Steven D ^c  

^a OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION   (United States)

^b DAKKRO Corporation   (United States)

^c VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^d U S ARMY CENTER FOR HEALTH PROMOTION AND PREVENTIVE MEDICINE   (United States)

Author keywords

2,4,6 Trinitrotoluene; Arabystoma tigrinum; Bioaccumulation; Dermal; Salamander

Indexed keywords

2 AMINODINITROTOLUENE; 4 AMINODINITROTOLUENE; AROCLOR 1260; POLYCHLORINATED BIPHENYL; TOLUENE DERIVATIVE; TRINITROTOLUENE; UNCLASSIFIED DRUG;

AMBYSTOMA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BODY BURDEN; CONTROLLED STUDY; ECOTOXICOLOGY; ENVIRONMENTAL EXPOSURE; FOOD CONTAMINATION; HISTOPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; SKIN ABSORPTION; SOIL POLLUTION; TISSUE DISTRIBUTION; TOXICOKINETICS;

AMBYSTOMA; AMBYSTOMA TIGRINUM; AMPHIBIA; AMPHIUMA MEANS; ANIMALIA; ARABYSTOMA; ARABYSTOMA TIGRINUM; CAUDATA; PANTHERA TIGRIS; VERTEBRATA;

EID: 0033048599     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1002/etc.5620180509     Document Type: Article

References (32)

1. U.S. Environmental Protection Agency. 1997. Ecological risk assessment guidance for superfund: Process for designing and conducting ecological risk assessments. EPA 540/R-97/006. Washington, DC.
2. Wentsel RS, La Point TW, Simini M, Checkai RT, Ludwig D, Brewer LW.1996. Tri-service procedural guidelines for ecological risk assessments. 56015/408/05/0000. Washington, DC, USA.
3. Duellman WE, Trueb L. 1986. Biology of Amphibians. McGrawHill, New York, NY, USA.
4. Phillips K. 1990. Where have all the frogs and toads gone? BioScience 40:422-424.
5. Wake DB. 1991. Declining amphibian populations. Science 253: 860.
6. Schmidt CW. 1997. Amphibian deformities continue to puzzle researchers. Environ Sci Technol 31:324-326.
7. Burkhart JG, Gardner HS. 1997. Non-mammalian and environmental sentinels in human health: Back to the future? Hum Ecol Risk Assess 3:309-328.
8. Cooke AS. 1981. Tadpoles as indicators of harmful levels of pollution in the field. Environ Pollut 25:123-133.
9. Sloof W, Baerselman R. 1980. Comparison of the usefulness of the Mexican axolotl (Ambystoma mexicanum) and the clawed frog (Xenopus laevis) in toxicological bioassays. Bull Environ Contam Toxicol 24:439-443.
10. Burton TM, Likens GE. 1975. Salamander populations and biomass in the Hubbard Brook Experimental Forest, New Hampshire. Copeia 1975(3):541-546.
11. Spector WS. 1956. Handbook of Biological Data. WB Saunders, Philadelphia, PA, USA.
12. Bishop SC. 1943. Handbook of Salamanders. Cornell University Press, Ithaca, NY, USA.
13. Gordon RE. 1968. Terrestrial activity of the spotted salamander, Ambystoma maculatum. Copeia 1968(4):879-880.
14. Semlitsch RD. 1981. Terrestrial activity and summer home range of the mole salamander (Ambystoma talpoideum). Can J Zool 59:315-322.
15. Walsh ME, Jenkins TF. 1992. Identification of TNT transformation products in soil. Special Report 92-16. U.S. Army Corps of Engineers, Cold Regions Research and Engineering Laboratory, Hanover, NH.
16. National Research Council. 1979. Polychlorinated Biphenyls. National Academy of Sciences, Washington, DC, USA.
17. Rice CP, O'Keefe P. 1995. Sources, pathways, and effects of PCBs, dioxins, and dibenzofurans. In Hoffman DJ, Rattner BA, Burton GA Jr, Cairns J Jr, eds, Handbook of Ecotoxicology, Lewis, Boca Raton, FL, USA, pp 424-468.
18. Dilley VJ, Tyson CA, Spanggord RJ, Sasmore DP, Newell GW, Dacre JC. 1982. Short-term oral toxicity of 2,3,4-trinitrotoluene in mice, rats, and dogs. J Toxicol Environ Health 9:565-585.
19. DiPinto LM, Coull BC, Chandler GT 1993. Lethal and sublethal effects of sediment-associated PCB Aroclor 1254 on a meiobenthic copepod. Environ Toxicol Chem 12:1909-1918.
20. Jaeger RG. 1992. Housing, handling, and nutrition of salamanders. In Shaeffer et al., eds, Care and Use of Amphibians, Reptiles and Fish in Research, Scientist Center for Animal Welfare, Bethesda, MD, USA, pp 25-29.
21. Hall RJ, Swineford D. 1979. Uptake of methoxychlor from food and water by the American toad (Bufo americanus). Bull Environ Contam Toxicol 23:335-337.
22. Reifenrath WG. 1994. Assessment of skin penetration of environmental contaminants in air and bioremediated soil utilizing the pig skin model. DAMD17-93-C-3167. Final Report. U.S. Army Medical Research, Development, Aquisition and Logistics Command, Ft. Detrick, Frederick, MD.
23. Biddinger GR, Gloss SP. 1984. The importance of trophic transfer in the bioaccumulation of chemical contamination in aquatic ecosystems. Residue Rev 91:103-145.
24. Ogata M, Fujisawa K, Ogino Y, Emiko M. 1984. Partition coefficients as a measure of bioconcentration potential of crude oil compounds in fish and shellfish. Bull Environ Contam Toxicol 33:561-567.
25. Kenaga EE. 1980. Correlation of bioconcentration factors of chemicals in aquatic and terrestrial organisms with their physical chemical properties. Environ Sd Technol 14:553-556.
26. Garten CT, Trabalka JR. 1983. Evaluation of models for predicting terrestrial food chain behavior of xenobiotics. Environ Sci Technol 17:590-595.
27. Travis CC, Arms AD. 1988. Relationship between dietary intake of organic chemicals and their concentrations in human adipose tissue and breast milk. Arch Environ Contam Toxicol 17:473-478.
28. Suter GW Jr. 1993. Ecological Risk Assessment. Lewis, Boca Raton, FL, USA.
29. Connell DW, Markwell RD. 1990. Bioaccumulation in the soil to earthworm system. Chemosphere 20:91-100.
30. Esser HO. 1986. A review of the correlation between physicochemical properties and bioaccumulation. Pestic Sci 17:265-276.
31. Hansen LG, Lambert RJ. 1987. Transfer of toxic substances by way of food animals: Selected examples. J Environ Qual 16:200-205.
32. Jaeger RG. 1980. Fluctuations in prey availability and food limitation for a terrestrial salamander. Oecologia 44:335-341.