Effects of an acidic fibroblast growth factor fragment analog on learning and memory and on medial septum cholinergic neurons in senescence- accelerated mice

Neuroscience

Volumn 92, Issue 4, 1999, Pages 1287-1294

  Sasaki, K ^a   Tooyama, I ^b   Li, A J ^c   Oomura, Y ^d   Kimura, H ^b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d Nippon Zoki Pharmaceutical Co   (Japan)

Author keywords

Acidic fibroblast growth factor fragment; Cholinergic neuron; Medial septum; Morris water maze task; Passive avoidance task; Senescence accelerated mice

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; CHOLINE ACETYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; DOSE RESPONSE; FOREBRAIN; IMMUNOREACTIVITY; LEARNING; MALE; MEMORY; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; SENESCENCE; SUBCUTANEOUS DRUG ADMINISTRATION;

AGING; ANIMALS; AVOIDANCE LEARNING; BRAIN; BRAIN CHEMISTRY; CHOLINE O-ACETYLTRANSFERASE; FIBROBLAST GROWTH FACTOR 1; IMMUNOHISTOCHEMISTRY; LEARNING; MAZE LEARNING; MEMORY; MICE; NEURONS; PARASYMPATHETIC NERVOUS SYSTEM; PEPTIDE FRAGMENTS;

EID: 0033048294     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00087-1     Document Type: Article

References (51)

1. Aguilar L.C., Islas A., Rosique P., Hernandez B., Portillo E., Herrera J.M., Cortes R., Cruz S., Alfaro F., Martin R., Cantu J.M. Psychometric analysis in children with mental retardation due to perinatal hypoxia treated with fibroblast growth factor (FGF) and showing improvement in mental development. J. Intellectual Disability Res. 37:1993;507-520.
2. Altavista M.C., Bentivoglio A.R., Crociani P., Rossi P., Albanses A. Age-dependent loss of cholinergic neurons in the basal ganglia of rats. Brain Res. 455:1988;177-181.
3. Altavista M.C., Rossi P., Bentivoglia A.R., Crociani P., Albanses A. Aging is associated with a diffuse impairment of forebrain cholinergic neurons. Brain Res. 508:1990;51-59.
4. Amarel D.G., Kurz J. An analysis of the origin of the cholinergic and noradrenergic septal projections to the hippocampal formation oh the rat. J. comp. Neurol. 240:1985;37-59.
5. Armstrong D.M., Saper C.B., Levey A.I., Wainer B.H., Terry R.D. Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. J. comp. Neurol. 216:1983;53-68.
6. Baird A. and Böhlen P. (1990) Fibroblast growth factors. In Peptide Growth Factors and Their Receptors II (eds Sporn M. D. and Roberts A. B.), pp. 1-64. Springer, Heidelberg.
7. Baird A., Walicke P.A. Fibroblast growth factors. Br. med. Bull. 45:1989;438-452.
8. Banks W.A., Kastin A.J. Physiological consequences of the passage of peptides across the blood-brain barrier. Rev. Neurosci. 4:1993;365-372.
9. Bartus R. T., Reginald L. D., Pontecorvo M. J. and Flicker C. (1985) The cholinergic hypothesis: a historical overview, current perspective, and future directions. In Memory Dysfunctions: An Integration of Animal and Human Research from Preclinical and Clinical Perspectives (eds Olton D. S., Gamzu E. and Corkin S.), pp. 332-358. New York Academy of Sciences.
10. Begley D.J. Peptides and the blood-brain barrier: the status of our understanding. Ann. N. Y. Acad. Sci. 739:1994;89-100.
11. Biegon A., Greenberger V., Segal M. Quantitative histochemistry of brain acetylcholinesterase and learning rate in aged rats. Neurobiol. Aging. 7:1986;215-217.
12. Bizon J.L., Lauterborn J.C., Isackson P.J., Gall C.M. Acidic fibroblast growth factor mRNA is expressed by basal forebrain and striatal cholinergic neurons. J. comp. Neurol. 366:1996;379-389.
13. Burgess W.H., Schaeffer A.M., Ravera M., Jaye M., Donohue P.J., Winkles J.A. Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue. J. Cell Biol. 111:1990;2129-2138.
14. Dutar P., Bassant M.H., Senut M.C., Lamour Y. The septohippocampal pathway: structure and function of a central cholinergic system. Physiol. Rev. 75:1995;393-427.
15. Figueiredo B.C., Piccardo P., Maysinger D., Clarke P.B., Cuello A.C. Effects of acidic fibroblast growth factor on cholinergic neurons of nucleus basalis magnocellularis and in a spatial memory task following cortical devascularization. Neuroscience. 56:1993;955-963.
16. Fischer W., Gage F.H., Björklund A. Degenerative changes in forebrain cholinergic nuclei correlate with cognitive impairments in aged rats. Eur. J. Neurosci. 1:1989;34-45.
17. Fischer W., Chen K.S., Gage F.H., Björklund A. Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging. Neurobiol. Aging. 13:1991;9-23.
18. Flood J.F., Morley J.E. Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM). Neurobiol. Aging. 14:1993;153-157.
19. Giménez-Gallego G., Cuevas P. Fibroblast growth factors, proteins with a broad spectrum of biological activities. Neurol. Res. 16:1994;313-316.
20. Gray J.A., McNaughton N. Comparison between the behavioral effects of septal and hippocampal lesions: a review. Neurosci. Biobehav. Rev. 7:1982;119-188.
21. Hisajima H., Miyagawa T., Saito H., Nishiyama N. Human acidic fibroblast growth factor has trophic effects on cultured neurons from multiple regions of brain and retina. Jap. J. Pharmac. 56:1991;495-503.
22. Imamura T., Engleka K., Zhan X., Tokita Y., Forough R., Roeder D., Jackson A., Maier J.A.M., Hla T., Maciag T. Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. Science. 249:1990;1567-1570.
23. Kimura H., McGeer P.L., Peng J.H., McGeer E.G. The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat. J. comp. Neurol. 200:1981;151-201.
24. Luine V.N., Renner K.J., Heady S., Jones K.J. Age- and sex-dependent decreases in ChAT in basal forebrain nuclei. Neurobiol. Aging. 7:1986;193-198.
25. Mehlman T., Burgess W.H. Detection and characterization of heparin-binding proteins with a gel overlay procedure. Analyt. Biochem. 188:1990;159-163.
26. Meisenberg G., Simmons W.H. Peptides and the blood brain barrier. Life Sci. 32:1983;2611-2623.
27. Miyamoto M., Kiyota Y., Nishiyama M., Nagaoka A. Senescence-accelerated mouse (SAM): age-related reduced anxiety-like behavior in the SAM-P/8 strain. Physiol. Behav. 51:1992;979-985.
28. Miyamoto M., Kiyota Y., Yamazaki N., Nagaoka A., Matsuo T., Nagawa Y., Takeda T. Age-related changes in learning and memory in the senescence-accelerated mouse (SAM). Physiol. Behav. 38:1986;399-409.
29. Mocchetti I., Erathall J.R. Neurotrophic factors in central nervous system trauma. J. Neurotrauma. 12:1995;853-870.
30. Molnar P., Gaal L., Horvath C. The impairment of long-term potentiation in rats with medial septal lesion and its restoration by cognition enhancers. Neurobiology. 2:1994;255-266.
31. Morris R.G.M. Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Meth. 11:1984;47-60.
32. Ohta A., Hirano T., Yagi H., Tanaka S., Hosokawa M., Takeda T. Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task. Brain Res. 498:1989;195-198.
33. Olton D. S. and Wenk G. L. (1987) Dementia: animal models of the cognitive impairments produced by degeneration of the basal forebrain cholinergic system. In Psychopharmacology: The Third Generation of Progress (ed. Meltzer H. Y.), pp. 941-953. Raven, New York.
34. Oomura Y., Sasaki K., Li A.-J., Yoshii H., Fukata Y., Yago H., Kimura H., Tooyama I., Hanai K., Nomura Y., Yanaihara N. Protection against impairment of memory and immunoreactivity in senescence-accelerated mice by acidic fibroblast growth factor. Ann. N. Y. Acad. Sci. 786:1996;337-347.
35. Pang K., Williams M.J., Olton D.S. Activation of the medial septal area attenuates LTP of the lateral perforant path and enhances heterosynaptic LTD of the medial perforant path in aged rats. Brain Res. 632:1993;150-160.
36. Pardridge W.M. Transport of nutrients and hormones through the blood-brain barrier. Fedn Proc. 43:1984;201-204.
37. Poduslo J.F., Curran G.L. Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Molec. Brain Res. 36:1996;280-286.
38. Sasaki K., Li A.-J., Oomura Y., Muto T., Hanai K., Tooyama I., Kimura H., Yanaihara N., Yagi H., Hori T. Effects of fibroblast growth factors and related peptides on food intake by rats. Physiol. Behav. 56:1994;211-218.
39. Sasaki K., Oomura Y., Suzuki K., Hanai K., Yagi H. Acidic fibroblast growth factor prevents death of hippocampal CA1 pyramidal cells following ischemia. Neurochem. Int. 21:1992;397-402.
40. Sievers J., Hausmann B., Unsicker K., Berry M. Fibroblast growth factors promote the survival of adult rat retinal ganglion cells after transection of the optic nerve. Neurosci. Lett. 76:1987;157-162.
41. Squire L.R. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol. Rev. 99:1992;195-231.
42. Stack R.W., Walsh T.J., Brucato F.H., Swartzwelder H.S. Medial septal benzodiazepine receptors modulate hippocampal evoked responses and long-term potentiation. Brain Res. 717:1996;12-21.
43. Stock A., Kuzis K., Woodward W.R., Nishi R., Eckenstein F.P. Localization of acidic fibroblast growth factor in specific subcortical neuronal populations. J. Neurosci. 12:1992;4688-4700.
44. Swanson L.W., Cowan W.M. The connections of the septal region in the rat. J. comp. Neurol. 186:1979;621-656.
45. Sweetnam P.M., Sanon H.R., White L.A., Brass B.J., Jaye M., Whittemore S.R. Differential effects of acidic and basic fibroblast growth factors on spinal cord cholinergic, GABAergic, and glutamatergic neurons. J. Neurochem. 57:1991;237-249.
46. Takeda T., Hosokawa M., Higuchi K. Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence. J. Am. geriatr. Soc. 39:1991;911-919.
47. Thomas K.A. Fibroblast growth factor. Fedn Proc. Fedn Am. Socs exp. Biol. 1:1987;434-440.
48. Tooyama I., Sasaki K., Oomura Y., Li A.-J., Kimura H. Effect of acidic fibroblast growth factor on basal forebrain cholinergic neurons in senescence accelerated mice. Expl Geront. 32:1997;171-179.
49. Wilkie A.O.M., Morriss-Kay G.M., Jones E.Y., Heath J.K. Functions of fibroblast growth factors and their receptors. Curr. Biol. 5:1995;500-507.
50. Yagi H., Katoh S., Akiguchi I., Takeda T. Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory. Brain Res. 474:1988;86-93.
51. Zlokovic B.V. Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier. Pharm. Res. 12:1995;1395-1406.