Engagement of the B-cell antigen receptor by antigen negatively regulates IgE production by antigen-specific B cells

Journal of Allergy and Clinical Immunology

Volumn 103, Issue 2 II, 1999, Pages 341-348

  Oshiba, Akihiro ^a   Gelfand, Erwin W ^a,b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b NONE   (United States)

Author keywords

Antigen specific b cells; B cell antigen receptor; Tetanus toxin

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN M; INTERLEUKIN 4; LYMPHOCYTE RECEPTOR; MESSENGER RNA;

ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOREGULATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADULT; ANTIBODY SPECIFICITY; ANTIGENS; ANTIGENS, CD40; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; EPITOPES, B-LYMPHOCYTE; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-4; INTERLEUKIN-6; RECEPTORS, ANTIGEN, B-CELL; RNA, MESSENGER; T-LYMPHOCYTES; TETANUS TOXIN;

EID: 0033048188     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0091-6749(99)70511-7     Document Type: Article

References (35)

1. Vitetta ES, Bossie A, Fernandez BR, Myers CD, Oliver KG, Sanders VM, et al. Interaction and activation of antigen-specific T and B cells. Immunol Rev 1987;99:193-239.
2. Noelle RJ, Snow EC. Cognate interactions between helper T cells and B cells. Immunol Today 1990;11:361-8.
3. Noelle RJ, Snow EC, Uhr JW, Vitetta ES. Activation of antigen-specific B cells: role of T cells, cytokines, and antigen in induction of growth and differentiation. Proc Natl Acad Sci USA 1983;80:6628-31.
4. H2 helper T cell lines. J Immunol 1988;141:2230-9.
5. Noelle RJ, McCann J, Marshall L, Bartlett WC. Cognate interactions between helper T cells and B cells. III. Contact-dependent, lymphokine-independent induction of B cell cycle entry by activated helper T cells. J Immunol 1989;143:1807-14.
6. Coffman RL, Lebman DA, Rothman P. Mechanism and regulation of immunoglobulin isotype switching. Adv Immunol 1993;54:229-70.
7. Gauchat JF, Lebman DA, Coffman RL, Gascan H, De VJ. Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production. J Exp Med 1990;172:463-73.
8. Parronchi P, Tiri A, Macchia D, De CM, Biswas P, Simonelli C, et al. Noncognate contact-dependent B cell activation can promote IL-4-dependent in vitro human IgE synthesis. J Immunol 1990;144:2102-8.
9. Thyphronitis G, Tsokos GC, June CH, Levine AD, Finkelman FD. IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon gamma. Proc Natl Acad Sci USA 1989;86:5580-4.
10. Vercelli D, Jabara HH, Arai K, Geha RS. Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens. J Exp Med 1989;169:1295-307.
11. + T cell clones. J Exp Med 1991;173:747-50.
12. Pene J, Rousset F, Briere F, Chretien I, Paliard X, Banchereau J, et al. IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. J Immunol 1988;141:1218-24.
13. Del PG, Maggi E, Parronchi P, Chretien I, Tiri A, Macchia D, et al. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988;140:4193-8.
14. Oshiba A, Renz H, Yata J, Gelfand EW. Isolation and characterization of human antigen-specific B lymphocytes. Clin Immunol Immunopathol 1994;72:342-9.
15. Oshiba A, Gelfand EW. Antigen-dependent regulation of IgE antibody production by human antigen-specific B cells. J Immunol 1996;157:4870-5.
16. Pellegrino MA, Ferrone S, Dierich MP, Reisfeld RA. Enhancement of sheep red blood cell human lymphocyte rosette formation by the sulfhydryl compound 2-amino ethylisothiouronium bromide. Clin Immunol Immunopathol 1975;3:324-33.
17. Kumagai K, Itoh K, Hinuma S, Tada M. Pretreatment of plastic Petri dishes with fetal calf serum: a simple method for macrophage isolation. J Immunol Methods 1979;29:17-25.
18. Oshiba A, Yata J. Increase of ovalbumin (OVA)-specific B cells in the peripheral blood of egg-allergic patients. J Allergy Clin Immunol 1991;87:729-36.
19. Nustad K, Johansen L, Ugelstad J, Ellingsen T, Berge A. Hydrophilic monodisperse particles as solid-phase material in immunoassays: comparison of shell-and-core particles with compact particles. Eur Surg Res 1984;2:80-7.
20. Egeland T, Hovdenes A, Lea T. Positive selection of antigen-specific B lymphocytes by means of immunomagnetic particles. Scand J Immunol 1988;27:439-44.
21. Engvall E, Perlmann P. Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. J Immunol 1972;109:129-35.
22. Lee WT, Conrad DH. Murine B cell hybridomas bearing ligand-inducible Fc receptors for IgE. J Immunol 1986;136:4573-80.
23. Renz H, Or R, Domenico J, Leung DY, Gelfand EW. Reciprocal regulatory effects of IL-4 on cell growth and immunoglobulin production in Ig-secreting human B-cell lines. Clin Immunol Immunopathol 1992;64:233-41.
24. Max EE, Battey J, Ney R, Kirsch IR, Leder P. Duplication and deletion in the human immunoglobulin epsilon genes. Cell 1982;29:691-9.
25. Ravetch JV, Siebenlist U, Korsmeyer S, Waldmann T, Leder P. Structure of the human immunoglobulin mu locus: characterization of embryonic and rearranged J and D genes. Cell 1981;27:583-91.
26. Kirsch IR, Morton CC, Nakahara K, Leder P. Human immunoglobulin heavy chain genes map to a region of translocations in malignant B lymphocytes. Science 1982;216:301-3.
27. Jabara HH, Fu SM, Geha RS, Vercelli D. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J Exp Med 1990;172:1861-4.
28. Jeppson JD, Pate L, Sakata N, Domenico J, Terada N, Gelfard EW. Requirement for dual signals by anti-CD40 and IL-4 for the induction of NF-κB, IL-6 and IgE in human B lymphocytes. J Immunol 1998;161:1738-42.
29. Wheeler K, Pound JD, Gordon J, Jefferis R. Engagement of CD40 lowers the threshold for activation of resting B cells via antigen receptor. Eur J Immunol 1993;23:1165-8.
30. Kearney JF, Cooper MD, Lawton AR. B lymphocyte differentiation induced by lipopolysaccharide. III. Suppression of B cell maturation by anti-mouse immunoglobulin antibodies. J Immunol 1976;116:1664-8.
31. Kearney JF, Klein J, Bockman DE, Cooper MD, Lawton AR. B cell differentiation induced by lipopolysaccharide. V. Suppression of plasma cell maturation by anti-mu: mode of action and characteristics of suppressed cells. J Immunol 1978;120:158-66.
32. Cooper MD, Kearney JF, Gathings WE, Lawton AR. Effects of anti-Ig antibodies on the development and differentiation of B cells. Immunol Rev 1980;52:29-53.
33. Pecanha LM, Yamaguchi H, Lees A, Noelle RJ, Mond JJ, Snapper CM. Dextran-conjugated anti-IgD antibodies inhibit T cell-mediated IgE production but augment the synthesis of IgM and IgG. J Immunol 1993;150:2160-8.
34. Zelazowski P, Collins JT, Dunnick W, Snapper CM. Antigen receptor cross-linking differentially regulates germ-line CH ribonucleic acid expression in murine B cells. J Immunol 1995;154:1223-31.
35. Burdin N, Van KC, Galibert L, Abrams JS, Wijdenes J, Banchereau J, et al. Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 1995;154:2533-44.