Characterization of the local and systemic immune responses in patients with cutaneous leishmaniasis due to Leishmania major

Clinical Immunology

Volumn 91, Issue 3, 1999, Pages 314-320

  Gaafar, A ^a   Veress, B ^b   Permin, H ^a   Kharazmi, A ^a   Theander, T G ^a   El Hassan, A M ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c NONE

Author keywords

Immune response; Immunopathology; In situ; Leishmania; Sudan

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; HUMAN; IMMUNE RESPONSE; LEISHMANIA MAJOR; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; REMISSION; SKIN BIOPSY; SKIN LEISHMANIASIS; T LYMPHOCYTE SUBPOPULATION;

EID: 0033047215     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.1999.4705     Document Type: Article

References (41)

1. Abdulla R. E., Sherif H. Epidemic of cutaneous leishmaniasis in nothern Sudan. Ann. Trop. Med. Parasitol. 72:1978;349-352.
2. Kadaro A. Y., Ghalib H. W., Ali M. S., Eltoum I., Ismail A., Gaafar A., Kemp M., Kordofani A. Y., Reed S. G., El Hassan A. M., Kharazmi A., Hag-Ali M., Mustafa M. D. Prevalence of cutaneous leishmaniasis along the Nile River north of Khartoum (Sudan) in the aftermath of an epidemic in 1985. Am. J. Trop. Med. Hyg. 48:1993;44-49.
3. El Safi S. H., Peters W., El Toum B., El Kadaro A. Y., Evans D. A. Studies on the leishmaniasis in the Sudan: Clinical and parasitological studies on cutaneous leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 85:1991;457-464.
4. Kubba R., Al-Gindan Y., El Hassan A. M., Omer A. H. S. Clinical diagnosis of Cutaneous leishmaniasis (oriental sore). J. Am. Acad. Dermatol. 16:1987;1183-1189.
5. Kemp M., Hey A., Kurtzhals J. A. L., Christensen C. B. V., Gaafar A., Mustafa M. D., Kordofani A. A. Y., Ismail A., Kharazmi A., Theander T. G. Dichotomi of the T cell response to Leishmania antigens. 1. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis. Clin. Exp. Immunol. 96:1994;410-415.
6. Gaafar A., El Kadaro A. Y., Theander T. G., Permin H., Ismail A., Kharazmi A., El Hassan A. M. The pathology of cutaneous leishmaniasis due toLeishmania major. Am. J. Trop. Med. Hyg. 52:1995;838-442.
7. Pirmez C., Cooper C., Paes-Oliveira M., Schubach A., Torigian V. K., Modlin R. Immunologic responsiveness in american cutaneous leishmaniasis lesions. J. Immunol. 145:1990;3100-3104.
8. Conceicao Silva F., Dorea R., Pirmez C., Schubach A. O., Cysne L., Coutinho S. G. Frequency ofLeishmania. Mem. Inst. Owaldo Cruz. 83:1988;403-406.
9. Modlin R. L., Melancon-Kaplan J., Young S. M. M., Pirmez C., Kino H., Convit J., Rea T. H., Bloom B. R. Learning from lesions: pattern of tissue inflammation in leprosy. Proc. Natl. Acad. Sci. USA. 85:1988;1213-1217.
10. Gaafar A., Kharazmi A., Ismail A., Kemp M., Hey A., Christensen C. B. V., Dafalla M., El Kadaro A. Y., El Hassan A. M., Theander T. G. Dichotomy of the T cell response toLeishmania. Clin. Exp. Immunol. 100:1995;239-245.
11. Gaafar A., Fadl A., El Kadaro A. Y., El Hassan M. M., Kemp M., Ismail A., Morgos S. A., El Hassan A. M. Sporotrichoid cutaneous leishmaniasis due toLeishmania major. Trans. R. Soc. Trop. Med. Hyg. 88:1994;552-554.
12. Hviid L., Albeck G., Hansen B., Theander T. G., Talbot A. Controlled-gradient cryopreservation of mononuclear cells: Description of a new method suitable for field conditions, and comparison with a conventional technique. J. Immunol. Methods. 157:1993;135-142.
13. Kemp M., Theander T. G., Handman E., Hey A. S., Kurtzhals J. A. L. Activation of human T lymphocytes by Leishmania lipophosphoglycan. Scand.J. Immunol. 33:1991;219-224.
14. Kurtzhals J AL, Hansen M. B., Hey A. S. Measurement of antigen-dependent interleukin-4 production by human peripheral blood mononuclear cells: Introduction of an amplification step using ionomycin and phorbol myristate acetate. J. Immunol. Methods. 156:1992;239-245.
15. Hviid L., Theander T. G., Abdulhadi N. H., Abu-Zeid Y. A., Bayoumi R. A., Jensen J. B. Transient depletion of T cells with high LFA-1 expression from peripheral circulation during acutePlasmodium falciparum. Eur. J. Immunol. 21:1991;1249-1253.
16. Hsu A., Raine L., Fanger H. Use of avidin-biotin peroxidase complex (ABC)in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedure. J. Histochem. Cytochem. 29:1981;577-580.
17. Hsu S., Soban E. Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry. J. Histochem. Cytochem. 30:1982;1079-1082.
18. Altman D. G. Practical Statistics for Medical Research. 1991;Chapman & Hall, London.
19. Barbier D., Goyot P., Dedet J. P. Leishmania braziliensis guyanwnsis. Trans. R. Soc. Trop. Med. Hyg. 79:1985;47-50.
20. Carvalho E. M., Johnson W. D., Barreto E., Marsden P. M., Costa J. L. M., Reed S., Rocha H. Cell mediated immunity in american cutaneous and mucosal leishmaniasis. J. Immunol. 135:1985;4144-4148.
21. Castes M., Agnelli A., Rondon A. J. Mechanisms associated with immunoregulation in human American cutaneous leishmaniasis. Clin. Exp. Immunol. 57:1984;279-286.
22. Castes M., Agnelli A., Verde O., Rondon A. J. Characterization of the cellular immune response in American cutaneous leishmaniasis. Clin. Immunol. Immunopathol. 27:1983;176-186.
23. Frankenburg S., Jonas F., Gross A., Klaus S. Development of in vitro parameters of cell-mediated immunity in the course of human cutaneous leishmaniasis infection. Am. J. Trop. Med. Hyg. 48:1993;512-518.
24. Jaffe C. L., Shor R., Trau H., Passwell J. H. Parasite antigens recognized by patients with cutaneous leishmaniasis. Clin. Exp. Immunol. 80:1990;77-82.
25. Modlin R. L., Tapia F. J., Bloom B. R., Gallinoto M. E., Castes M., Rondon A. J., Rea T. H., Convit J. In situ characterization of the cellular immune response in American cutaneous leishmaniasis. Clin. Exp. Immunol. 60:1985;248.
26. Ridel P. R., Esterre P., Dedet J. P., Pradinaud R., Santoro F., Capron A. Killer cells in human cutaneous leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 82:1988;223-226.
27. Martinez-Arends A., Tapia F. J., Caceres-Dittmar G., Mosca W., Valecillos L., Convit J. Immunocytochemical characterization of immune cells in lesions of American cutaneous leishmaniasis using novel T cell markers. Acta Tropica. 49:1991;271-280.
28. Esterre P., Dedet J. P., Frenay C., Chevallier M., Grimaud J. A. Cell populations in the lesion of human cutaneous leishmaniasis: A light microscopical, immunohistochemical and ultrastructural study. Virchows Arch. A. Anat. 421:1992;239-247.
29. Lima H. C., Vasconcelosm A. W., David J. R., Lerner E. A. American cutaneous leishmaniasis: In situ characterization of the cellular immune response with time. Am. J. Trop. Med. Hyg. 50:1994;743-747.
30. Isaza D. M., Restrepo M., Restrepo R., Caceres-Dittmar G., Tapia F. J. Immunocytochemical and histopathologic characterization of lesions from patients with localized cutaneous leishmaniasis caused byLeishmania panamensis. Am. J. Trop. Med. Hyg. 55:1996;365-369.
31. El Hassan A. M., Kubba R., Al Gindan Y. M. Lymphocyte phenotypes and HLA-Dr expression in the lesions of cutaneous leishmaniasis and their draining lymph nodes. Ann. Saud. Med. 7:1987;212-220.
32. Veress B., El Hassan A. M. Immunohistochemical demonstration of S-100 protein antigen-containing cells in chronic cutaneous leishmaniasis. Acta Pathol. Microbiol. Immunol. Scand. [Sect A]. 93:1985;331-334.
33. Nilsen R., Mshana R. N. In situ characterization of the cutaneous immune response in Ethiopian cutaneous leishmaniasis. Scand. J. Immunol. 26:1987;503-512.
34. Huzar M., Shor R., Trau H., Gazit E., Passwell J. H. T cell phenotypes in the lesion of patients with cutaneous leishmaniasis. Clin. Exp. Immunol. 12:1987;103-107.
35. Ridley D. S. The evolution of the lesion in cutaneous leishmaniasis. J. Pathol. 141:1983;83-96.
36. Ridley M., Ridley D. S. Cutaneous leishmaniasis, immune complex formation and necrosis in the acute phase. Br. J. Exp. Pathol. 65:1984;327-336.
37. Muller I., Pedrazzini T., Kropf P., Lois J., Milon G. Establishment of resistance toLeishmania major. Int. Immunol. 3:1991;587-597.
38. Da-Cruz A., Conceicao-Silva F., Bertho A. L., Coutinho S. G. Leishmania. Infect. Immun. 62:1994;2614-2618.
39. Harms G., Zwingenberger K., Chehade A. K., Talhari S., Racs P., Moukeh A., Douba M., Nakel L., Naiff R. D., Kremsner P. G., Feldmeyer H., Bienzle U. Effects of intradermal gamma-interferon in cutaneous leishmaniasis. Lancet. i:1989;1287-1292.
40. El Hassan A. M., Gaafar A., Theander T. G. Antigen-Presenting cells in human cutaneous leishmaniasis due toLeishmania major. Clin. Exp. Immunol. 99:1995;445-453.
41. Kubeyinne E. P., Belagavi C. S., Jamil Y. A. Cutaneous leishmaniasis in expatriates in Northern Saudi Arabia. East Afr. Med. 74:1997;249-251.