Early-onset and late-onset depression are independent of the genetic polymorphism of apolipoprotein E

Dementia and Geriatric Cognitive Disorders

Volumn 10, Issue 4, 1999, Pages 258-261

  Papassotiropoulos, Andreas ^a   Bagli, Metin ^b   Jessen, Frank ^b   Rao, Marie Luise ^b   Schwab, Sibylle G ^b   Heun, Reinhard ^b  

^a UNIVERSITY OF BONN   (Germany)

^b NONE

Author keywords

Alzheimer's disease; Apolipoprotein E; Association; Depression; Early onset; Late onset; Polymorphism; Survival analysis

Indexed keywords

APOLIPOPROTEIN E; DNA;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

AGE FACTORS; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; DEPRESSIVE DISORDER; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SURVIVAL ANALYSIS;

EID: 0033047210     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017129     Document Type: Article

References (22)

1. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD: Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-1981.
2. Copeland JR, Davidson IA, Dewey ME, Gilmore C, Larkin BA, McWilliam C, Saunders PA, Scott A, Sharma V, Sullivan C: Alzheimer's disease, other dementias, depression and pseudodementia: Prevalence, incidence and three-year outcome in Liverpool. Br J Psychiatry 1992;161:230-239.
3. Speck CE, Kukull WA, Brenner DE, Bowen JD, McCormick WC, Teri L, Pfanschmidt ML, Thompson JD, Larson EB: History of depression as a risk factor for Alzheimer's disease. Epidemiology 1995;6:366-369.
4. Alexopoulos GS, Abrams RC: Depression in Alzheimer's disease. Psychiatr Clin North Am 1991;14:327-340.
5. Krishnan KR, Tupler LA, Ritchie JC Jr, McDonald WM, Knight DL, Nemeroff CB, Carroll BJ: Apolipoprotein E-epsilon 4 frequency in geriatric depression. Biol Psychiatry 1996;40:69-71.
6. Steffens DC, Plassman BL, Helms MJ, Welsh-Bohmer KA, Saunders AM, Breitner JCS: A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease. Biol Psychiatry 1997;41:851-856.
7. Ramachandran G, Marder K, Tang M, Schofield PW, Chun MR, Devanand DP, Stern Y, Mayeux R: A preliminary study of apolipoprotein E genotype and psychiatric manifestations of Alzheimer's disease. Neurology 1996;47: 256-259.
8. Cantillon M, Harwood D, Barker W, St George-Hyslop P, Tsuda T, Ekatarina R, Duara R: No association between apolipoprotein E genotype and late-onset depression in Alzheimer's disease. Biol Psychiatry 1997;41:246-248.
9. Forsell Y, Corder EH, Basun H, Lannfelt L, Viitanen M, Winblad B: Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+. Biol Psychiatry 1997;42:898-903.
10. Heidrich A, Thome J, Rosler M, Baumer A: Apolipoprotein E-epsilon 4 allele frequency in late-onset depression. Biol Psychiatry 1997;41: 912-913.
11. Henderson AS, Korten AE, Jacomb PA, Mackinnon AJ, Jorm AF, Christensen H, Rodgers B: The course of depression in the elderly: A longitudinal community-based study in Australia. Psychol Med 1997;27:119-129.
12. Lopez OL, Kamboh MI, Becker JT, Kaufer DI, DeKosky ST: The apolipoprotein E epsilon 4 allele is not associated with psychiatric symptoms or extrapyramidal signs in probable Alzheimer's disease. Neurology 1997;49:794-797.
13. Lyketsos CG, Baker L, Warren A, Steele C, Brandt J, Steinberg M, Kopunek S, Baker A: Depression, delusions, and hallucinations in Alzheimer's disease: No relationship to apolipoprotein E genotype. J Neuropsychiatry Clin Neurosci 1997;9:64-67.
14. Schmand B, Hooijer C, Jonker C, Lindeboom J, Havekes LM: Apolipoprotein E phenotype is not related to late-life depression in a population-based sample. Soc Psychiatry Psychiatr Epidemiol 1998;33:21-26.
15. Zubenko GS, Henderson R, Stiffler JS, Stabler S, Rosen J, Kaplan BB: Association of the APOE epsilon 4 allele with clinical subtypes of late life depression. Biol Psychiatry 1996;40: 1008-1016.
16. McKhann G, Drachmen D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Atzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
17. Hixson JE, Vernier DT: Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990; 31:545-548.
18. Pearlson GD, Ross CA, Lohr WD, Rovner BW, Chase GA, Folstein MF: Association between family history of affective disorder and the depressive syndrome of Alzheimer's disease. Am J Psychiatry 1990;147:452-456.
19. Strauss ME, Ogrocki PK: Confirmation of an association between family history of affective disorder and the depressive syndrome in Alzheimer's disease. Am J Psychiatry 1996;153: 1340-1342.
20. Zung WW: Depression in the normal aged. Psychosomatics 1967;8:287-292.
21. Maier W, Lichtermann D, Minges J, Heun R, Hallmayer J, Klingler T: Unipolar depression in the aged: Determinants of familial aggregation. J Affect Disord 1991;23:53-61.
22. Brodaty H, Peters K, Boyce P, Hickie I, Parker G, Mitchell P, Wilhelm K: Age and depression. J Affect Disord 1991;23:137-149.