Exposure assessment: Serum levels of TCDD in Seveso, Italy

Environmental Research

Volumn 80, Issue 2 II, 1999, Pages

  Needham, L L ^a   Gerthoux, P M ^b   Patterson Jr , D G ^a   Brambilla, P ^b   Smith, S J ^a   Sampson, E J ^a   Mocarelli, P ^b  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b DESIO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN;

ADOLESCENT; ADULT; AGE; AGED; BLOOD ANALYSIS; BLOOD LEVEL; CHILD; CONFERENCE PAPER; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; FEMALE; FISH; GENDER; HIGH RISK POPULATION; HUMAN; ITALY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RISK ASSESSMENT;

EID: 0033047126     PISSN: 00139351     EISSN: None     Source Type: Journal    
DOI: 10.1006/enrs.1998.3928     Document Type: Conference Paper

References (14)

1. Andrews, J. S., Jr., Garrett, W. A., Jr., Patterson, D. G., Jr., Needham, L. L., Roberts, D. W., Bagby, J. R., Anderson, J. E., Hoffman, R. E., and Schramm, W. (1987). 2,3,7,8-TCDD levels in adipose tissue of persons with no known exposure and in exposed persons. Chemosphere 18, 499-506.
2. Belli, G., Cerlesi, S., Kapila, S., Ratti, S. P., and Yanders, A. (1989). Geometrical description of the TCDD contamination of Times Beach. Chemosphere 18, 1251-1255.
3. Caramaschi, F., Del Corno, G., Favaretti, C., Giambelluca, S., Montesarchio, E., and Fara, G. (1981). Chloracne following environmental contamination by TCDD in Seveso, Italy. Int. J. Epidemiol. 10, 135-143.
4. Cerlesi, S., DiDomenico, A., and Ratti, S. (1989). Recovery yields of early analytical procedures to detect 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in soil samples at Seveso, Italy. Chemosphere 18, 989-1003.
5. Fingerhut, M. A., Halperin, W. E., Marlow, D. A., Piacitelli, L. A., Honchar, P. A., Sweeney, M. H., Greife, A. L., Dill, P. A., Steenland, K., and Suruda, A. J. (1991). Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. New Engl. J. Med. 324, 212-218.
6. Hay, A. (1976). Toxic cloud over Seveso. Nature (London), 262, 636-638.
7. Landi, M. T., Needham, L. L., Lucier, G., Mocarelli, P., Bertazzi, P. A., Caporaso, N. A. (1997). Concentrations of dioxin 20 years after exposure. Lancet 1(349), 1811.
8. Mocarelli, P., Brambilla, P., Gerthoux, P. M., Patterson, D. G., Jr., and Needham, L. L. (1996). Change in sex ratio with exposure to dioxin. Lancet 1(348), 409.
9. Mocarelli, P., Needham, L. L., Marocchi, A., Patterson, D. G., Jr., Brambilla, P., Gerthoux, P. M., Meazza, L., and Carreri, V. (1991). Serum concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin and test results from selected residents of Seveso, Italy. J. Toxicol. Environ. Health 32, 357-366.
10. Needham, L. L. (1994). Examples of measuring internal dose for assessing exposure in epidemiological studies. In "Environmental Epidemiology: Effects of Environmental Chemicals on Human Health (W. M. Draper, Ed.), Advances in Chemistry Series," Vol. 241. American Chemical Society, Washington.
11. Needham, L. L., Gerthoux, P. M., Patterson, D. G., Jr., Brambilla, P., Pirkle, J. L., Tramacere, P. L., Turner, W. E., Beretha, C., Sampson, E. J., and Mocarelli, P. (1994). Half-life of 2,3,7,8-tetrachlorodibenzo-p-dioxin in serum of Seveso adults. Interim report. Organohalogen Compounds 21, 81-85.
12. Needham, L. L., Gerthoux, P. M., Patterson, D. G., Jr., Brambilla, P., Turner, W. E., Beretha, C., Pirkle, J. L., Colombo, L., Sampson, E. J., Tramaere, P. L., Signorini, S., Meazza, L., Carreri, V., Jackson, R. J., and Mocarelli, P. (1997/1998). Serum dioxin levels in Seveso, Italy population in 1976. Teratogen. Carcinogen. Mutagen. 17, 225-240.
13. Needham, L. L., Pirkle, J. L., Burse, V. W., Patterson, D. G., Jr., and Holler, J. S. (1991). Case studies of relationship between external dose and internal dose. J. Exp. Environ. Epidemiol. 1(Suppl.) 209-221.
14. Patterson, D. G., Jr., Hampton, L., Lapeza, C. R., Jr., Pelser, W. T., Green, V., Alexander, L., and Needham, L. L. (1987). High resolution gas chromatographic/high resolution mass spectrometer analysis of human serum on a whole-weight and lipid basis for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Anal. Chem. 59, 2000-2005.