Thapsigargin analogues for targeting programmed death of androgen-independent prostate cancer cells

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 7, 1999, Pages 1273-1280

  Brogger Christensen S ^a   Andersen, Annette ^a   Kromann, Hasse ^a   Treiman, Marek ^b   Tombal, Bertrand ^c   Denmeade, Sam ^c   Isaacs, John T ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Apoptosis; Prodrug; Prostate cancer; Prostate specific antigen; Thapsigargin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); TERPENOID; THAPSIGARGIN; THAPSIGARGIN DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROSTATE CANCER; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANDROGENS; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM-TRANSPORTING ATPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MUSCLE, SKELETAL; PRODRUGS; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RABBITS; SARCOPLASMIC RETICULUM; STRUCTURE-ACTIVITY RELATIONSHIP; THAPSIGARGIN; TUMOR CELLS, CULTURED;

EID: 0033046929     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00074-7     Document Type: Article

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