Brainstem mechanisms of autonomic dysfunction in encephalopathy- associated Shiga toxin 2 intoxication

Annals of Neurology

Volumn 45, Issue 6, 1999, Pages 716-723

  Yamada, Yoji ^a   Fujii, Jun ^a   Murasato, Yoshinobu ^a   Nakamura, Tadashi ^a   Hayashida, Yoshiaki ^a   Kinoshita, Yoshimasa ^a   Yutsudo, Takashi ^b   Matsumoto, Tetsuro ^a   Yoshida, Shin Ichi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SHIGA TOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC DYSFUNCTION; BRAIN DISEASE; BRAIN STEM; BREATHING RATE; CAUSE OF DEATH; CONTROLLED STUDY; DIARRHEA; HEART RATE; HYPOTENSION; INTOXICATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; NORADRENALIN BLOOD LEVEL; OXYGEN TENSION; PARALYSIS; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RABBIT;

ANIMALS; AUTONOMIC NERVOUS SYSTEM DISEASES; BACTERIAL TOXINS; BLOOD PRESSURE; BODY TEMPERATURE; BRAIN STEM; HEART RATE; MAGNETIC RESONANCE IMAGING; MALE; RABBITS; RESPIRATION; SHIGA TOXINS; TIME FACTORS;

EID: 0033046741     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199906)45:6<716::AID-ANA5>3.0.CO;2-N     Document Type: Article

References (40)

1. Riley LW, Remis RS, Helgerson SD, et al. Hemorrhagic colitis associated with a rare Escherichia coli serotype. N Engl J Med 1983;308:681-685
2. Karmali MA, Petric M, Lim C, et al. The association between idiopathic hemolytic-uremic syndrome and infection by verotoxin-producing Escherichia coli. J Infect Dis 1985;151: 775-782
3. Karmali MA. Infection by verocytotoxin-producing Escherichia coli. Clin Microbiol Rev 1989;2:15-38
4. Hamano S, Nakanishi Y, Nara T, et al. Neurological manifestations of hemorrhagic colitis in the outbreak of Escherichia coli O157:H7 infection in Japan. Acta Pediatr 1991;82:454-458
5. Rooney JC, Anderson RM, Hopkins IJ. Clinical and pathological aspects of central nervous system involvement in the haemolytic uraemic syndrome. Aust Pediatr J 1971;7:28-33
6. Siegler RL, Pavia AT, Christofferson RD, Milligan MK. A 20-year population-based study of postdiarrheal hemolytic uremic syndrome in Utah. Pediatrics 1994;94:35-40
7. Siegler RL. Spectrum of extrarenal involvement in postdiarrheal hemolytic uremic syndrome. J Pediatr 1994;125:511-518
8. Tzipori S, Chow CW, Powell HR. Cerebral infection with Escherichia coli O157:H7 in humans and gnotobiotic piglets. J Clin Pathol 1988;41:1099-1103
9. Upadhyaya K, Barwick K, Fishaut M, et al. The importance of nonrenal involvement in hemolytic-uremic syndrome. Pediatrics 1980;65:115-120
10. Francis DH, Moxley RA, Andraos CY. Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7. Infect Immun 1989;57:1339-1342
11. Robson WL, Leung AK, Montgomery MD. Causes of death in hemolytic uremic syndrome. Child Nephrol Urol 1991;11: 228-233
12. Bos AP, Donckerwolcke RA, van Vught AJ. The hemolytic-uremic syndrome: prognostic significance of neurological abnormalities. Helv Paediatr Acta 1985;40:381-389
13. Sanada M, Okano H, Yokota S, et al. Electrocardiographic study of sinus bradycardia associated with enterohemorrhagic Escherichia coli O157:H7 infection [in Japanese]. Kokyu To Junkan 1993;41:653-657
14. Fujii J, Kita T, Yoshida S, et al. Direct evidence of neuron impairment by oral infection with verotoxin-producing Escherichia coli O157:H- in mitomycin-treated mice. Infect Immun 1994;62:3447-3453
15. Barrett TJ, Potter ME, Wachsmuth IK. Continuous peritoneal infusion of Shiga-like toxin II (SLT II) as a model for SLT-II-induced disease. J Infect Dis 1989;159:774-777
16. Bridgwater FAJ, Morgan RS, Rowson KEK, Wright GP. The neurotoxin of Shigella shigae: morphological and functional lesions produced in the central nervous system of rabbits. Br J Exp Pathol 1955;36:447-453
17. Fujii J, Kinoshita Y, Kita T, et al. Magnetic resonance imaging and histopathological study of brain lesions in rabbits given intravenous verotoxin 2. Infect Immun 1996;64:5053-5060
18. Mizuguchi M, Tanaka S, Fujii I, et al. Neuronal and vascular pathology produced by verocytotoxin 2 in the rabbit central nervous system. Acta Neuropathol 1996;91:254-262
19. Richardson SE, Rotman TA, Jay V, et al. Experimental verocytotoxemia in rabbits. Infect Immun 1992;60:4154-4167
20. Zoja C, Corna D, Farina C, et al. Verotoxin glycolipid receptors determine the localization of microangiopathic process in rabbits given verotoxin-1. J Lab Clin Med 1992;120:229-238
21. Lingwood CA. Role of verotoxin receptors in pathogenesis. Trends Microbiol 1996;4:147-153
22. Lord JM, Roberts LM, Robertus JD. Ricin: structure, mode of action, and some current applications. Fed Am Soc Exp Biol J 1994;8:201-208
23. Christiansen VJ, Hsu CH, Dormer KJ, Robinson CP. The cardiovascular effects of ricin in rabbits. Pharmacol Toxicol 1994; 74:148-152
24. Ma L, Hsu CH, Patterson E, et al. Ricin depresses cardiac function in the rabbit heart. Toxicol Appl Pharmacol 1996; 138:72-76
25. Christiansen VJ, Hsu CH, Zhang L, Robinson CP. Effects of ricin on the ability of rabbit arteries to contract and relax. J Appl Toxicol 1995;15:37-43
26. Zhou ZZ, Wurster RD, Jones SB. Arterial baroreflexes are not essential in mediating sympathoadrenal activation in conscious endotoxic rats. J Auton Nerv Syst 1992;39:1-12
27. Hirakawa H, Nakamura T, Hayashida Y. Effect of carbon dioxide on autonomic cardiovascular responses to systemic hypoxia in conscious rats. Am J Physiol 1997;273:747-754
28. Kent BB, Drane JW, Blumenstein B, Manning JW. A mathematical model to assess changes in the baroreceptor reflex. Cardiology 1972;57:295-310
29. Nakamura T, Hayashida Y. Autonomic cardiovascular responses to smoke exposure in conscious rats. Am J Physiol 1992;262: 738-745
30. Yutsudo T, Nakabayashi N, Hirayama T, Takeda Y. Purification and some properties of a vero toxin from Escherichia coli O157:H7 that is immunologically unrelated to Shiga toxin. Micrab Pathog 1987;3:21-30
31. Nohta H, Mitsui A, Ohkura Y. Spectrofluorimetric determination of catecholamines with 1,2-diphenylethylenediamine. Anal Chim Acta 1984;165:171-176
32. Sugimoto N, Haque A, Horiguchi Y, Matsuda M. Coronary vasoconstriction is the most probable cause of death of rats intoxicated with botulinolysin, a hemolysin produced by Clostridium botulinum. Toxicon 1995;33:1215-1230
33. Sakurai J, Oshita Y, Fujii Y. Effect of Clostridium perfringens alpha toxin on the cardiovascular system of rats. Toxicon 1985; 23:903-912
34. Asmuth DM, Olson RD, Hackett SP, et al. Effects of Clostridium perfringens recombinant and crude phospholipase C and θ-toxin on rabbit hemodynamic parameters. J Infect Dis 1995; 172:1317-1323
35. Feuerstein G, Goldstein DS, Ramwell PW, et al. Cardiorespiratory, sympathetic and biochemical responses to T-2 toxin in the guinea pig and rat. J Pharmacol Exp Ther 1985;232:786-794
36. Bitzan MM, Wang Y, Lin J, Marsden PA. Verotoxin and ricin have novel effects on preproendothelin-1 expression but fail to modify nitric oxide synthase (ec NOS) expression and NO production in vascular endothelium. J Clin Invest 1998;101:372-382
37. Endo Y, Tsurugi K. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. J Biol Chem 1987;262:8128-8130
38. Peterson DF, Coote JH, Gilbey MP, Futuro-Neto HA. Differential pattern of sympathetic outflow during upper airway stimulation with smoke. Am J Physiol 1983;245:433-437
39. Lin YC. Autonomic nervous control of cardiovascular response during diving in the rat. Am J Physiol 1974;227:601-605
40. Bielaszewska M, Clarke I, Karmali MA, Petric M. Localization of intravenously administered verocytotoxins (Shiga-like toxin) 1 and 2 in rabbits immunized with homologous and heterologous toxoids and toxin subunits. Infect Immun 1997;65: 2509-2516