Mutation detection by chemical cleavage

Genetic Analysis - Biomolecular Engineering

Volumn 14, Issue 5-6, 1999, Pages 165-168

  Cotton, R G H ^a  

^a Daly Wing St Vincent's H ^*  (Australia)

Author keywords

Chemical cleavage; Mutation; Sequencing

Indexed keywords

CONFERENCE PAPER; COST BENEFIT ANALYSIS; GENE MUTATION; GENE SEQUENCE; MEDICAL RESEARCH; MOLECULAR GENETICS; PRIORITY JOURNAL;

DNA MUTATIONAL ANALYSIS; HUMANS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SEQUENCE ANALYSIS, DNA;

EID: 0033046466     PISSN: 10503862     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-3862(98)00021-7     Document Type: Conference Paper

References (11)

1. Cotton R.G.H. Mutation Detection. 1997;Oxford University Press, Oxford.
2. Cotton R.G.H., Edkins E., Forrest S. Mutation Detection: A Practical Approach. 1998;IRL Press.
3. Taylor G.R. Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA. 1997;CRC Press, Boca Ratan.
4. Fodor S.P.A. Massively parallel genomics. Science. 277:1997;393-395.
5. Ganguly A., Williams C. Detection of mutations in multi-exon genes: comparison of conformation sensitive gel electrophoresis and sequencing strategies with respect to cost and time for finding mutations. Human Mutat. 9:1997;339-343.
6. Cotton R.G.H., Rodrigues N.R., Campbell R.D. Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations. Proc. Natl. Acad. Sci. USA. 85:1988;4397-4401.
7. Ellis T.P., Humphrey K.E., Smith M.J., Cotton R.G.H. Chemical cleavage of mismatch: A new look at an established method. Human Mutat. 11:1998;345-353.
8. Rowley G., Saad S., Giannelli F., Green P.M. Ultrarapid mutation detection by multiplex, solid phase chemical cleavage. Genomics. 30:1995;574-582.
9. Roberts E., Deeble V.J., Woods G., Taylor G.R. Potassium permanganate and tetraethylammonium chloride are a safe and effective substitute for osmium tetroxide in solid-phase fluorescent chemical cleavage of mismatch. Nucleic Acids Res. 25(6):1997;3377-3378.
10. Verpy E., Biasotto T., Tosi M. Efficient detection of point mutations on color-coded strands of target DNA. Proc. Natl. Acad. Sci. USA. 91:1994;1873-1877.
11. Cotton R.G.H. Slowly, but surely towards better scanning for mutations (Invited Review). Trends Genet. 13:1997;43-46.