Cognitive decline in late-life schizophrenia: A longitudinal study of geriatric chronically hospitalized patients

Biological Psychiatry

Volumn 45, Issue 1, 1999, Pages 32-40

  Harvey, Philip D ^a   Silverman, Jeremy M ^a   Mohs, Richard C ^a   Parrella, Michael ^a   White, Leonard ^a   Powchik, Peter ^b   Davidson, Michael ^c   Davis, Kenneth L ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b US Pharmaceuticals   (United States)

^c SHEBA MEDICAL CENTER   (Israel)

Author keywords

Cognitive functioning; Geriatric psychosis; Longitudinal studies; Schizophrenia

Indexed keywords

AGED; ARTICLE; COGNITIVE DEFECT; FEMALE; FOLLOW UP; FUNCTIONAL DISEASE; HOSPITALIZATION; HUMAN; INSTITUTIONALIZATION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RATING SCALE; SCHIZOPHRENIA;

AGED; CHRONIC DISEASE; COGNITION DISORDERS; EDUCATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INPATIENTS; LONGITUDINAL STUDIES; MALE; PSYCHIATRIC STATUS RATING SCALES; RISK FACTORS; SCHIZOPHRENIC PSYCHOLOGY;

EID: 0033045762     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(98)00273-X     Document Type: Article

References (38)

1. Arnold S.E., Gur R.E., Shapiro R.M., et al. Prospective clinicopathological studies of schizophrenia: Accrual and assessment of patients. Am J Psychiatry. 152:1995;731-737.
2. Berg L. Clinical dementia rating (CDR). Psychopharmacol Bull. 24:1988;637-639.
3. Bleuler M. The Schizophrenias: Long Term Patient and Family Studies. 1978;Yale University Press, New Haven, CT.
4. Casanova M.F., Carosella N.W., Gold J.M., Kleinman J.E., Weinberger D.R. A topographical study of senile placques and neurofibrillary tangles in the hippocampi of patients with Alzheimer's disease and cognitively impaired patients with schizophrenia. Psychiatry Res. 49:1993;41-62.
5. Ciompi L. Catamnestic long-term study on the course of life and aging of schizophrenics. Schizophr Bull. 6:1980;606-618.
6. Davidson M., Harvey P.D., Powchik P., et al. Severity of symptoms in geriatric chronic schizophrenic patients. Am J Psychiatry. 152:1995;197-207.
7. Davidson M., Harvey P.D., Welsh K., Powchik P., Putnam K.M., Mohs R.C. Cognitive impairment in old-age schizophrenia: A comparative study of schizophrenia and Alzheimer's disease. Am J Psychiatry. 153:1996;1274-1279.
8. Davis K.L., Buchsbaum M.S., Shihabuddin L., et al. Ventricular enlargement in poor outcome schizophrenia. Biol Psychiatry. 43:1998;783-793.
9. Delisi L., Sakuma M., Tew W., Kushrer M., Hoff A., Grimson R. Schizophrenia as a chronic active brain process: A study of progressive brain structural change subsequent to the onset of psychosis. Psychiatry Res Brain Imaging. 74:1997;129-140.
10. Folstein M.F., Folstein S.E., McHugh P.R. "Mini-Mental State." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 12:1975;189-198.
11. Goldberg T., Hyde T.M., Kleinman J.E., Weinberger D.R. Course of schizophrenia: Neuropsychological evidence for static encephalopathy. Schizophr Bull. 19:1993;787-804.
12. Harding C.M., Brooks G.W., Ashikaga T., Strauss J.S., Breier A. The Vermont Longitudinal study of persons with severe mental illness: II. Long term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia. Am J Psychiatry. 144:1987;727-735.
13. Haroutunian V., Davidson M., Kanof P.D., et al. Cortical cholinergic markers in schizophrenia. Schizophr Res. 12:1994;137-144.
14. Harvey P.D., Davidson M., Powchik P., Parrella M., White L., Mohs R.C. Assessment of dementia in elderly schizophrenics with structured rating scales. Schizophr Res. 7:1992;85-90.
15. Harvey P.D., Mohs R.C., Davidson M. Leukotomy and aging in chronic schizophrenia: A followup study 40 years after psychosurgery. Schizophr Bull. 19:1993;723-732.
16. Harvey P.D., Powchik P., Mohs R.C., Davidson M. Memory functions in geriatric chronic schizophrenic patients: A neuropsychological study. J Neuropsychiatry Clin Neurosci. 7:1995;207-212.
17. Harvey P.D., White L., Parrella M., et al. The longitudinal stability of cognitive impairment in schizophrenia: Mini-Mental State scores at one and two year follow-ups in geriatric inpatients. Br J Psychiatry. 166:1995;630-633.
18. Harvey P.D., Lombardi J., Leibman M., et al. Cognitive impairment and negative symptoms in schizophrenia: A prospective study of their relationship. Schizophr Res. 22:1996;223-231.
19. Harvey P.D., Leff J., Trieman N., Davidson M. Cognitive and adaptive impairment in late-life schizophrenia: A cross-national study in the US and UK. Int J Geriatr Psychiatry. 12:1997;1001-1007.
20. Harvey P.D., Lombardi J., Leibman M., et al. Age-related differences in formal thought disorder in chronically hospitalized schizophrenic patients: A cross-sectional study across 9 decades. Am J Psychiatry. 154:1997;205-210.
21. Harvey PD, Parrella M, White L, Mohs RC, Davis KL (in press a): Convergence of cognitive and functional decline in poor outcome schizophrenia. Schizophr Res.
22. Harvey P.D., Howanitz E., Parrella M., et al. Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: A comparison across treatment sites. Am J Psychiatry. 155:1998;1080-1086.
23. Heaton R.K., Pendleton M.G. Use of neuropsychological tests to predict patients' everyday functioning. J Consult Clin Psychol. 49:1981;807-821.
24. Hyde T.M., Nawroz S., Goldberg T.E., Kleinman J.E., Weinberger D.R. Is there cognitive decline in schizophrenia? A cross-sectional study. Br J Psychiatry. 164:1994;494-500.
25. Jaskiw G., Juliano D., Goldberg T.E., Hertzman M., Urow-Hamell D., Weinberger D.R. Cerebral ventricular enlargement in schizophreniform disorder does not progress: A seven-year followup study. Schizophr Res. 14:1994;23-29.
26. Jeste D.V., Harris M.J., Krull A., Kuck J., McAdams L.A., Heaton R. Late-onset schizophrenia: Clinical and neuropsychological characteristics. Am J Psychiatry. 172:1995;722-730.
27. Kaplan H.I., Sadock B.J., Grebb J.A. Kaplan and Sadock's Synopsis of Clinical Psychiatry. 7th ed. 1994;Williams and Wilkins, Baltimore.
28. Kay S.R. Positive and Negative Syndromes in Schizophrenia. 1991;Brunner/Mazel, New York.
29. Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry. 52:1995;998-1007.
30. Perlick D., Mattis S., Stastny P., Teresi J. Neuropsychological discriminators of long-term inpatient or outpatient status in chronic schizophrenia. J Neuropsychiatry Clin Neurosci. 4:1992;428-434.
31. Powchik P., Davidson M., Haroutunian V., Gabriel S.M., Purohit D.P., Perl D.P., Harvey P.D., Davis K.L. Postmortem studies in schizophrenia. Schizophr Bull. 24:1998;325-341.
32. Purohit D.P., Perl D.P., Haroutunian V., et al. Alzheimer's disease and related neurodegenerative diseases in elderly schizophrenia patients: A postmortem neuropathologic study of 100 cases. Arch Gen Psychiatry. 55:1998;205-211.
33. Putnam K.M., Harvey P.D., Parrella M., White L., Powchik P., Davidson M. Symptom stability in geriatric chronic schizophrenic inpatients: A one-year follow-up study. Biol Psychiatry. 39:1996;92-99.
34. Rapoport J.L., Giedd J., Kumra S., et al. Childhood onset schizophrenia: Progressive ventricular change during adolescence. Arch Gen Psychiatry. 54:1997;897-903.
35. Rosen W.G., Mohs R.C., Davis K.L. A new rating scale for Alzheimer's disease. Am J Psychiatry. 141:1984;1356-1364.
36. Russell A.J., Munro J.C., Jones P.B., Hemsley D.R., Murray R.M. Schizophrenia and the myth of intellectual decline. Am J Psychiatry. 154:1997;635-639.
37. Saykin A.J., Shtasel D.L., Gur R.E., et al. Neuropsychological deficits in neuroleptic naive patients with first episode schizophrenia. Arch Gen Psychiatry. 54:1994;124-131.
38. Stern R.G., Mohs R.C., Davidson M., et al. A longitudinal study of Alzheimer's disease: Measurement, rate and predictors of cognitive deterioration. Am J Psychiatry. 151:1994;390-396.